Author

Christopher G. Thomson

Observed names: Christopher Thomson, Thomson, Christopher, Thomson, Christopher G.

Observed institutions: Heriot-Watt University, MSD (UK) Limited (United Kingdom), Pharmaron (United Kingdom), Novartis Institutes for BioMedical Research

ORCID: 0000-0001-7224-3667

Observed ORCID: 0000-0001-7224-3667

OpenAlex ID: A5073723486

An efficient solid phase synthetic route to 1,3-disubstituted 2,4(1H,3H)-Quinazolinediones suitable for combinatorial synthesis

1996 · Adrian L. Smith, Christopher G. Thomson, et al. · Bioorganic & Medicinal Chemistry Letters · 67

Thiazoles and thiopyridines: novel series of high affinity h5HT7 ligands

2003 · Christopher G. Thomson, Margaret S. Beer, et al. · Bioorganic & Medicinal Chemistry Letters · 33

Continuous-flow synthesis and application of polymer-supported BODIPY Photosensitisers for the generation of singlet oxygen; process optimised by in-line NMR spectroscopy

2020 · Christopher G. Thomson, Callum M. S. Jones, et al. · Journal of Flow Chemistry · 28

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Additive manufacturing of intricate and inherently photocatalytic flow reactor components

2020 · Adilet Zhakeyev, Mary C. Jones, et al. · Additive manufacturing · 23

Optimization of Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for Duration of Action, as an Inhaled Therapy for Lung Remodeling in Pulmonary Arterial Hypertension

2016 · Duncan E. Shaw, Ferheen Baig, et al. · Journal of Medicinal Chemistry · 23

Expanding the Tool Kit of Automated Flow Synthesis: Development of In-line Flash Chromatography Purification

2021 · Christopher G. Thomson, Colin Banks, et al. · The Journal of Organic Chemistry · 22

A convenient method for the preparation of aryl cyclopropyl ethers from phenols

1999 · Gregory J. Hollingworth, Kevin Dinnell, et al. · Tetrahedron Letters · 20

Synthesis of a Novel Type of 2,3′‐BIMs via Platinum‐Catalysed Reaction of Indolylallenes with Indoles

2018 · Lisa Cooper, José Miguel Alonso, et al. · Chemistry - A European Journal · 17

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Discovery of HC-7366: An Orally Bioavailable and Efficacious GCN2 Kinase Activator

2024 · Christopher G. Thomson, Thomas D. Aicher, et al. · Journal of Medicinal Chemistry · 16

Structure-guided design of a selective inhibitor of the methyltransferase KMT9 with cellular activity

2024 · Sheng Wang, Sebastian O. Klein, et al. · Nature Communications · 16

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Synthesis and structure–activity relationships of 8-azabicyclo[3.2.1]octane benzylamine NK1 antagonists

2005 · Christopher G. Thomson, Emma Carlson, et al. · Bioorganic & Medicinal Chemistry Letters · 16

Sarcosine based indandione hGlyT1 inhibitors

2005 · Christopher G. Thomson, Karen Duncan, et al. · Bioorganic & Medicinal Chemistry Letters · 15

Development of autotaxin inhibitors: A series of zinc binding triazoles

2018 · Christopher G. Thomson, Darren Le Grand, et al. · Bioorganic & Medicinal Chemistry Letters · 12

Flash chemistry enables high productivity metalation-substitution of 5-alkyltetrazoles

2021 · Jeff Y. F. Wong, Christopher G. Thomson, et al. · Chemical Science · 11

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The Photochemical Mediated Ring Contraction of 4H-1,2,6-Thiadiazines To Afford 1,2,5-Thiadiazol-3(2H)-one 1-Oxides

2023 · Emmanouil Broumidis, Christopher G. Thomson, et al. · Organic Letters · 5

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Development of autotaxin inhibitors: A series of tetrazole cinnamides

2020 · Christopher G. Thomson, Darren Le Grand, et al. · Bioorganic & Medicinal Chemistry Letters · 4

Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 Agonists

2023 · Christopher G. Thomson, Kelly Boss, et al. · ACS Medicinal Chemistry Letters · 2

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In Vivo Tumor Growth Control by General Control Nonderepressible 2–Targeting Agents Results from Kinase Activation

2025 · Feven Tameire, Paulina Wojnarowicz, et al. · Molecular Cancer Therapeutics · 1

Synthesis of useful fragments in drug discovery: 2-Amino-5-tert-butylpyridine and its oxidised analogues

2011 · Christopher G. Thomson, John Reilly, et al. · Bioorganic & Medicinal Chemistry Letters · 1

Supplementary Figure S5 from In Vivo Tumor Growth Control by General Control Nonderepressible 2–Targeting Agents Results from Kinase Activation