Get started
Author

Jürgen Harder

Observed names: Harder, J., Harder, Jürgen, J Harder, J. Harder, J., Harder, Juergen Harder, Jurgen Harder, Jürgen Harder,  J. Harder
Observed institutions: University of Bonn, Universität Hamburg, University of Michigan, Christian-Albrechts-Universität zu Kiel, Medizinische Hochschule Hannover, University Medical Center Hamburg-Eppendorf, University Hospital Schleswig-Holstein, Michigan Medicine, Universitäts Hautklinik Kiel, U-M Rogel Cancer Center, Technical University of Munich
ORCID: 0000-0002-4075-4603
Observed ORCID: 0000-0002-4075-4603
OpenAlex ID: A5074088715
A peptide antibiotic from human skin
1997 · J. Harder, J. Bartels, et al. · Nature · 1,363
Isolation and Characterization of Human μ-Defensin-3, a Novel Human Inducible Peptide Antibiotic
2001 · Jürgen Harder, Joachim Bartels, et al. · Journal of Biological Chemistry · 1,311
PDF
NOD2 (CARD15) mutations in Crohn’s disease are associated with diminished mucosal α-defensin expression
2004 · J Wehkamp, J Harder, et al. · Gut · 823
PDF
Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection
2004 · Regine Gläser, Jürgen Harder, et al. · Nature Immunology · 652
NF-κB- and AP-1-Mediated Induction of Human Beta Defensin-2 in Intestinal Epithelial Cells byEscherichia coliNissle 1917: a Novel Effect of a Probiotic Bacterium
2004 · Jan Wehkamp, Jürgen Harder, et al. · Infection and Immunity · 474
PDF
Human beta-defensin-2
1999 · Jens-M Schröder, Jürgen Harder · The International Journal of Biochemistry & Cell Biology · 453
Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions
2011 · Yvonne Dombrowski, Mark Peric, et al. · Science Translational Medicine · 431
RNase 7, a Novel Innate Immune Defense Antimicrobial Protein of Healthy Human Skin
2002 · Jürgen Harder, Jens-Michael Schröder · Journal of Biological Chemistry · 425
Mucoid Pseudomonas aeruginosa , TNF-α, and IL-1 β, but Not IL-6, Induce Human β-Defensin-2 in Respiratory Epithelia
2000 · Jürgen Harder, Ulf Meyer-Hoffert, et al. · American Journal of Respiratory Cell and Molecular Biology · 414
Probiotic lactobacilli and VSL#3 induce enterocyte β-defensin 2
2008 · M Schlee, J Harder, et al. · Clinical & Experimental Immunology · 359
NOD2/CARD15 Mediates Induction of the Antimicrobial Peptide Human Beta-defensin-2
2005 · Eske Voss, Jan Wehkamp, et al. · Journal of Biological Chemistry · 344
PDF
Inducible and Constitutive β-Defensins Are Differentially Expressed in Crohn's Disease and Ulcerative Colitis
2003 · Jan Wehkamp, Juergen Harder, et al. · Inflammatory Bowel Diseases · 295
Enhanced Expression and Secretion of Antimicrobial Peptides in Atopic Dermatitis and after Superficial Skin Injury
2010 · Jürgen Harder, Stefanie Dressel, et al. · Journal of Investigative Dermatology · 259
Antimicrobial skin peptides and proteins
2006 · J. M. Schröder, J. Harder · Cellular and Molecular Life Sciences · 253
Epidermal EGFR Controls Cutaneous Host Defense and Prevents Inflammation
2013 · Beate M. Lichtenberger, Peter A. Gerber, et al. · Science Translational Medicine · 240
Activation of the Nlrp3 Inflammasome by Streptococcus pyogenes Requires Streptolysin O and NF-κB Activation but Proceeds Independently of TLR Signaling and P2X7 Receptor
2009 · Jürgen Harder, Luigi Franchi, et al. · The Journal of Immunology · 237
PDF
Uncovering the evolutionary history of innate immunity: The simple metazoan Hydra uses epithelial cells for host defence
2008 · Thomas C.G. Bosch, René Augustin, et al. · Developmental & Comparative Immunology · 234
Cutting Edge: Critical Role for Mesothelial Cells in Necrosis-Induced Inflammation through the Recognition of IL-1α Released from Dying Cells
2008 · Tatjana Eigenbrod, Jong-Hwan Park, et al. · The Journal of Immunology · 228
Antitumor Activity of the Antimicrobial Peptide Magainin II against Bladder Cancer Cell Lines
2006 · Jan Lehmann, Margitta Retz, et al. · European Urology · 228
Psoriatic scales: a promising source for the isolation of human skin-derived antimicrobial proteins
2005 · Jürgen Harder, Jens-Michael Schröder · Journal of Leukocyte Biology · 228
The Antimicrobial Protein Psoriasin (S100A7) Is Upregulated in Atopic Dermatitis and after Experimental Skin Barrier Disruption
2008 · Regine Gläser, Ulf Meyer-Hoffert, et al. · Journal of Investigative Dermatology · 214
Differential Gene Induction of Human β-Defensins (hBD-1, -2, -3, and -4) in Keratinocytes Is Inhibited by Retinoic Acid
2004 · Jürgen Harder, Ulf Meyer-Hoffert, et al. · Journal of Investigative Dermatology · 212
PDF
UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo
2009 · Regine Gläser, Fatemeh Navid, et al. · Journal of Allergy and Clinical Immunology · 199
Antimicrobial peptides of the Cecropin-family show potent antitumor activity against bladder cancer cells
2008 · Henrik Suttmann, Margitta Retz, et al. · BMC Urology · 173
PDF
Antileukoprotease in Human Skin: An Antibiotic Peptide Constitutively Produced by Keratinocytes
1998 · Oliver Wiedow, Jürgen Harder, et al. · Biochemical and Biophysical Research Communications · 168
Works count: 188
Citation count: 14,410
H-index: 53
I10-index: 114
Year
Topic
Type