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Jennifer L. Goeckeler-Fried

Observed names: Goeckeler-Fried, Jennifer L., J Goeckeler, J. Goeckeler-Fried, J. L. Goeckeler, Jen Goeckler-Fried, Jennifer L. Goeckeler
Observed institution: University of Pittsburgh
ORCID: 0000-0001-5940-9917
Observed ORCID: 0000-0001-5940-9917
OpenAlex ID: A5075161663
The Requirement for Molecular Chaperones during Endoplasmic Reticulum-associated Protein Degradation Demonstrates That Protein Export and Import Are Mechanistically Distinct
1999 · Jeffrey L. Brodsky, Eric D. Werner, et al. · Journal of Biological Chemistry · 287
BiP and Sec63p are required for both co- and posttranslational protein translocation into the yeast endoplasmic reticulum.
1995 · J L Brodsky, J Goeckeler, et al. · Proceedings of the National Academy of Sciences · 254
The Function of the Yeast Molecular Chaperone Sse1 Is Mechanistically Distinct from the Closely Related Hsp70 Family
2004 · Lance Shaner, Amy Trott, et al. · Journal of Biological Chemistry · 99
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Overexpression of Yeast Hsp110 Homolog Sse1p Suppressesydj1-151Thermosensitivity and Restores Hsp90-dependent Activity
2002 · Jennifer L. Goeckeler, Andi Stephens, et al. · Molecular Biology of the Cell · 88
The Hsp110 Molecular Chaperone Stabilizes Apolipoprotein B from Endoplasmic Reticulum-associated Degradation (ERAD)
2007 · Stacy L. Hrizo, Viktoria Gusarova, et al. · Journal of Biological Chemistry · 86
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The yeast Hsp110, Sse1p, exhibits high‐affinity peptide binding
2008 · Jennifer L. Goeckeler, Anthony P. Petruso, et al. · FEBS Letters · 61
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Molecular chaperones and substrate ubiquitination control the efficiency of endoplasmic reticulum‐associated degradation
2010 · J. L. Goeckeler, J. L. Brodsky · Diabetes Obesity and Metabolism · 37
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics
2016 · W. Joon Chung, Jennifer L. Goeckeler-Fried, et al. · PLoS ONE · 28
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Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding
2018 · Annette N. Chiang, Mary Liang, et al. · Bioorganic & Medicinal Chemistry · 21
Structural Basis for the Inhibitory Effects of Ubistatins in the Ubiquitin-Proteasome Pathway
2017 · Mark A. Nakasone, Timothy A. Lewis, et al. · Structure · 18
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Improved correction of F508del-CFTR biogenesis with a folding facilitator and an inhibitor of protein ubiquitination
2021 · Jennifer L. Goeckeler-Fried, Rajiah Aldrin Denny, et al. · Bioorganic & Medicinal Chemistry Letters · 13
SLC26A9 is selected for endoplasmic reticulum associated degradation (ERAD) via Hsp70-dependent targeting of the soluble STAS domain
2021 · Patrick G. Needham, Jennifer L. Goeckeler-Fried, et al. · Biochemical Journal · 6
Cloning, sequencing, and nucleolar targeting of the basal-body-binding nucleolar protein BN46/51
1999 · Gina M. Trimbur, Jennifer L. Goeckeler, et al. · Journal of Cell Science · 4
Role of the NuRD complex and altered proteostasis in cancer cell quiescence
2025 · Qi Jiang, Michelle Ertel, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 3
Identification of the MRTFA/SRF pathway as a critical regulator of quiescence and chemotherapy resistance in cancer
2026 · Santiago Panesso-Gómez, Alexander J. Cole, et al. · Cancer Letters · 2
Reconstitution of CFTR ubiquitination identifies lysine-420 as a regulator of cell surface residence and current
2025 · Jennifer L. Goeckeler-Fried, Xuemei Zeng, et al. · Biochemistry and Biophysics Reports · 1
The Hsp110 molecular chaperone stabilizes apolipoprotein B from endoplasmic reticulum associated degradation
2007 · Stacy Lynn Hrizo, Viktoria Gusarova, et al. · The FASEB Journal · 1
Targeting HDAC and proteostasis to eradicate quiescent cancer cells
2026 · Qi Jiang, Michelle Ertel, et al. · Cancer Gene Therapy
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365 Differential effects of (S)- and (R)-vanzacaftor on BKCa potentiation and CFTR correction
2024 · A. Kolski-Andreaco, J. Goeckeler-Fried, et al. · Journal of Cystic Fibrosis
653 Targeting CFTR ubiquitination to augment therapeutic strategies
2022 · J. Goeckeler-Fried, S. Estabrooks, et al. · Journal of Cystic Fibrosis
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NMR studies revealed structural basis for the inhibitory effects of ubistatins in the ubiquitin-mediated signaling pathways
2018 · Nakasone, Mark, Lewis, Thimothy, et al. · HAL
Works count: 21
Citation count: 1,009
H-index: 11
I10-index: 11
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