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Lara Perryman

RETRACTED ARTICLE: The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase
2015 · Thomas R. Cox, Robin M. H. Rumney, et al. · Nature · 482
Paediatric and adult malignant glioma: close relatives or distant cousins?
2012 · Chris Jones, Lara Perryman, et al. · Nature Reviews Clinical Oncology · 243
Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling
2015 · Pau Creixell, Erwin M. Schoof, et al. · Cell · 183
MGMT-Independent Temozolomide Resistance in Pediatric Glioblastoma Cells Associated with a PI3-Kinase–Mediated HOX /Stem Cell Gene Signature
2010 · Nathalie Gaspar, Lynley Marshall, et al. · Cancer Research · 163
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A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer
2023 · Jessica L. Chitty, Michelle Yam, et al. · Nature Cancer · 147
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Molecular and Phenotypic Characterisation of Paediatric Glioma Cell Lines as Models for Preclinical Drug Development
2009 · Dorine A. Bax, Suzanne E. Little, et al. · PLoS ONE · 129
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The lysyl oxidase like 2/3 enzymatic inhibitor, PXS‐5153A, reduces crosslinks and ameliorates fibrosis
2018 · Heidi Schilter, Alison D. Findlay, et al. · Journal of Cellular and Molecular Medicine · 117
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EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines
2009 · Dorine A. Bax, Nathalie Gaspar, et al. · Clinical Cancer Research · 101
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Lysyl Oxidase in Cancer Research
2014 · Lara Perryman, Janine T Erler · Future Oncology · 51
Enhanced Efficacy of IGF1R Inhibition in Pediatric Glioblastoma by Combinatorial Targeting of PDGFRα/β
2011 · Aleksandra Bielen, Lara Perryman, et al. · Molecular Cancer Therapeutics · 45
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Dependence of Wilms tumor cells on signaling through insulin-like growth factor 1 in an orthotopic xenograft model targetable by specific receptor inhibition
2012 · Aleksandra Bielen, Gary Box, et al. · Proceedings of the National Academy of Sciences · 34
PROTACs Targeting MLKL Protect Cells from Necroptosis
2023 · Oliver H. Rathje, Lara Perryman, et al. · Journal of Medicinal Chemistry · 32
An activity‐based bioprobe differentiates a novel small molecule inhibitor from a LOXL2 antibody and provides renewed promise for anti‐fibrotic therapeutic strategies
2021 · Alison Findlay, Craig Turner, et al. · Clinical and Translational Medicine · 31
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Evaluation of the Response of Intracranial Xenografts to VEGF Signaling Inhibition Using Multiparametric MRI
2017 · Jessica K.R. Boult, Gary Box, et al. · Neoplasia · 17
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Over-expression of p53 mutants in LNCaP cells alters tumor growth and angiogenesis in vivo
2006 · L.A. Perryman, J.M. Blair, et al. · Biochemical and Biophysical Research Communications · 16
Pan-lysyl oxidase inhibition disrupts fibroinflammatory tumor stroma, rendering cholangiocarcinoma susceptible to chemotherapy
2024 · Paul R. Burchard, Luis I. Ruffolo, et al. · Hepatology Communications · 14
Investigating intracranial tumour growth patterns with multiparametric MRI incorporating Gd‐DTPA and USPIO‐enhanced imaging
2016 · Jessica K.R. Boult, Marco Borri, et al. · NMR in Biomedicine · 13
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Fibrosis in Mesothelioma: Potential Role of Lysyl Oxidases
2022 · Lara Perryman, Steven G. Gray · Cancers · 12
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Comparison of 18F-FET and 18F-FLT small animal PET for the assessment of anti-VEGF treatment response in an orthotopic model of glioblastoma
2015 · Mette Kjoelhede Nedergaard, Signe Regner Michaelsen, et al. · Nuclear Medicine and Biology · 12
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The small molecule LOXL2 inhibitor SNT-5382 reduces cardiac fibrosis and achieves strong clinical target engagement
2025 · Lara Perryman, Alison Findlay, et al. · Scientific Reports · 11
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Brain Cancer Spreads
2014 · Lara Perryman, Janine T. Erler · Science Translational Medicine · 10
Retraction Note: The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase
2023 · Thomas R. Cox, Robin M. H. Rumney, et al. · Nature · 3
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LOX Inhibition Disrupts a Collagen–Integrin–MYC Axis to Suppress Progression of Invasive Lobular Carcinoma
2026 · Renée L. Flaherty, Flavia Hughes, et al. · Cancer Research · 2
Matrix structure and microenvironment dynamics correlate with chemotherapy response in ovarian cancer
2026 · Florian Laforêts, Panoraia Kotantaki, et al. · iScience · 2
High Grade Gliomas and Dipg
2014 · C. F. Classen, D. William, et al. · Neuro-Oncology · 1
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Works count: 67
Citation count: 1,872
H-index: 15
I10-index: 21
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