Author

K.L. Kavanagh

Observed names: K. Kavanagh, K. L. Kavanagh, KATHRYN L. KAVANAGH, Kathryn Kavanagh, Kathryn L Kavanagh, Kathryn L. KAVANAGH, Kathryn L. Kavanagh, Kathryn L. KAVANAGH, Kathryn L. Kavanagh, Kavanagh, Kathryn L

Institution: University of Oxford

Observed institutions: University of Aberdeen, Nuffield Orthopaedic Centre, National Institute for Health and Care Research, University of Oxford, Graz University of Technology, NIHR Oxford Biomedical Research Centre, University of Cincinnati, University of Birmingham, University of California, Davis, The University of Texas at Austin

OpenAlex ID: A5076200465

Medium- and short-chain dehydrogenase/reductase gene and protein families

2008 · K. L. Kavanagh, H. Jörnvall, et al. · Cellular and Molecular Life Sciences · 908

PDF

The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs

2006 · Kathryn L. Kavanagh, Kunde Guo, et al. · Proceedings of the National Academy of Sciences · 537

The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative

2008 · Bengt Persson, Yvonne Kallberg, et al. · Chemico-Biological Interactions · 397

Bisphosphonates

2007 · R. GRAHAM G. RUSSELL, ZHIDAO XIA, et al. · Annals of the New York Academy of Sciences · 391

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

2007 · Stanley S. Ng, Kathryn L. Kavanagh, et al. · Nature · 329

Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming

2011 · Grazyna Kochan, Tobias Krojer, et al. · Proceedings of the National Academy of Sciences · 249

Aldehyde Dehydrogenase 7A1 (ALDH7A1) Is a Novel Enzyme Involved in Cellular Defense against Hyperosmotic Stress

2010 · Chad Brocker, Natalie Lassen, et al. · Journal of Biological Chemistry · 200

PDF

Structure and function of human 17β-hydroxysteroid dehydrogenases

2006 · Petra Lukacik, Kathryn L. Kavanagh, et al. · Molecular and Cellular Endocrinology · 192

The Crystal Structure of Human Geranylgeranyl Pyrophosphate Synthase Reveals a Novel Hexameric Arrangement and Inhibitory Product Binding

2006 · Kathryn L. Kavanagh, James E. Dunford, et al. · Journal of Biological Chemistry · 167

PDF

Structure–Activity Relationships Among the Nitrogen Containing Bisphosphonates in Clinical Use and Other Analogues: Time-Dependent Inhibition of Human Farnesyl Pyrophosphate Synthase

2008 · James E. Dunford, Aaron A. Kwaasi, et al. · Journal of Medicinal Chemistry · 151

PDF

Reversible Sequestration of Active Site Cysteines in a 2Fe-2S-bridged Dimer Provides a Mechanism for Glutaredoxin 2 Regulation in Human Mitochondria

2006 · Catrine Johansson, Kathryn L. Kavanagh, et al. · Journal of Biological Chemistry · 147

PDF

The crystal structure of human GLRX5: iron–sulfur cluster co-ordination, tetrameric assembly and monomer activity

2010 · Catrine Johansson, Annette K. Roos, et al. · Biochemical Journal · 123

PDF

The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography

2004 · Barbara PETSCHACHER, Stefan LEITGEB, et al. · Biochemical Journal · 123

PDF

Ribosomal oxygenases are structurally conserved from prokaryotes to humans

2014 · Rasheduzzaman Chowdhury, Rok Sekirnik, et al. · Nature · 105

The Structure of Apo and Holo Forms of Xylose Reductase, a Dimeric Aldo-Keto Reductase from Candida tenuis,

2002 · Kathryn L. Kavanagh, Mario Klimacek, et al. · Biochemistry · 104

A non‐enzymatic function of 17β‐hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival

2010 · Katharina Rauschenberger, Katja Schöler, et al. · EMBO Molecular Medicine · 100

PDF

Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity

2007 · Petra Lukacik, Brigitte Keller, et al. · Biochemical Journal · 99

PDF

Mechanism and Substrate Recognition of Human Holo ACP Synthase

2007 · Gabor Bunkoczi, Saloni Pasta, et al. · Chemistry & Biology · 93

PDF

Crystal Structure of the 2-Oxoglutarate- and Fe(II)-Dependent Lysyl Hydroxylase JMJD6

2010 · Monica Mantri, Tobias Krojer, et al. · Journal of Molecular Biology · 92

Structural basis of fumarate hydratase deficiency

2011 · Sarah Picaud, Kathryn L. Kavanagh, et al. · Journal of Inherited Metabolic Disease · 86

PDF

Structure of Human Phytanoyl-CoA 2-Hydroxylase Identifies Molecular Mechanisms of Refsum Disease*

2005 · Michael A. McDonough, Kathryn L. Kavanagh, et al. · Journal of Biological Chemistry · 84

UDP-glucose dehydrogenase: structure and function of a potential drug target

2010 · Sigrid Egger, Apirat Chaikuad, et al. · Biochemical Society Transactions · 80

Structure and Mechanism of Human UDP-glucose 6-Dehydrogenase

2011 · Sigrid Egger, Apirat Chaikuad, et al. · Journal of Biological Chemistry · 75

PDF

Structure of xylose reductase bound to NAD+ and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductases

2003 · Kathryn L. KAVANAGH, Mario KLIMACEK, et al. · Biochemical Journal · 70

PDF

SALMON: Solvent Accessibility, Ligand binding, and Mapping of ligand Orientation by NMR Spectroscopy

2007 · Christian Ludwig, Paul J. A. Michiels, et al. · Journal of Medicinal Chemistry · 68

PDF

Works count: 157

Citation count: 5,809

H-index: 35

I10-index: 48