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Author

Clark Q. Pan

Observed names: Clark Pan, Clark Q Pan, Clark Qun Pan, Pan, Clark Q.
Observed institutions: Fox Chase Cancer Center, University of California, Los Angeles, Genentech, Sanofi (France), Sanofi (United States), Takeda (United States), Bayer (Germany)
ORCID: 0000-0001-5110-1803
Observed ORCID: 0000-0001-5110-1803
OpenAlex ID: A5076375328
Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment
2010 · Baisong Mei, Clark Pan, et al. · Blood · 235
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Site-Specific Antibody–Drug Conjugation through Glycoengineering
2014 · Qun Zhou, James E. Stefano, et al. · Bioconjugate Chemistry · 228
Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats
2004 · Christopher J. Parsons, Blair U. Bradford, et al. · Hepatology · 199
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Development of a simple and rapid method for producing non‐fucosylated oligomannose containing antibodies with increased effector function
2007 · Qun Zhou, Srinivas Shankara, et al. · Biotechnology and Bioengineering · 189
Variable Structures of Fis-DNA Complexes Determined by Flanking DNA – Protein Contacts
1996 · Clark Q. Pan, Steven E. Finkel, et al. · Journal of Molecular Biology · 169
A Potent and Highly Selective VPAC2 Agonist Enhances Glucose-Induced Insulin Release and Glucose Disposal
2002 · Manami Tsutsumi, Thomas H. Claus, et al. · Diabetes · 126
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Structure of the lipoprotein lipase–GPIHBP1 complex that mediates plasma triglyceride hydrolysis
2018 · Gabriel Birrane, Anne P. Beigneux, et al. · Proceedings of the National Academy of Sciences · 98
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Role of viral hemagglutinin glycosylation in anti-influenza activities of recombinant surfactant protein D
2008 · Kevan L Hartshorn, Richard Webby, et al. · Respiratory Research · 90
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Mutational analysis of human DNase I at the DNA binding interface: Implications for DNA recognition, catalysis, and metal ion dependence
1998 · Clark Q. Pan, Jana S. Uumer, et al. · Protein Science · 89
Design of a Long Acting Peptide Functioning as Both a Glucagon-like Peptide-1 Receptor Agonist and a Glucagon Receptor Antagonist
2006 · Clark Q. Pan, Joanne M. Buxton, et al. · Journal of Biological Chemistry · 71
X-ray and Biochemical Analysis of N370S Mutant Human Acid β-Glucosidase
2010 · Ronnie R. Wei, Heather Hughes, et al. · Journal of Biological Chemistry · 68
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Cloning and characterization of an actin-resistant DNase I-like endonuclease secreted by macrophages
1998 · Will F Baron, Clark Q Pan, et al. · Gene · 63
Engineering Hyperactive Variants of Human Deoxyribonuclease I by Altering Its Functional Mechanism
1997 · Clark Q. Pan, Robert A. Lazarus · Biochemistry · 62
Dual-acting peptide with prolonged glucagon-like peptide-1 receptor agonist and glucagon receptor antagonist activity for the treatment of type 2 diabetes
2007 · Thomas H Claus, Clark Q Pan, et al. · Journal of Endocrinology · 46
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Strategies for Neoglycan Conjugation to Human Acid α-Glucosidase
2011 · Qun Zhou, James E. Stefano, et al. · Bioconjugate Chemistry · 45
Improved Potency of Hyperactive and Actin-resistant Human DNase I Variants for Treatment of Cystic Fibrosis and Systemic Lupus Erythematosus
1998 · Clark Q. Pan, Tony H. Dodge, et al. · Journal of Biological Chemistry · 44
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Glycan Structure Determinants for Cation-Independent Mannose 6-Phosphate Receptor Binding and Cellular Uptake of a Recombinant Protein
2013 · Qun Zhou, Luis Z. Avila, et al. · Bioconjugate Chemistry · 43
Generation of Highly Selective VPAC2 Receptor Agonists by High Throughput Mutagenesis of Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-activating Peptide
2003 · Stephanie L. Yung, Fernando Dela Cruz, et al. · Journal of Biological Chemistry · 42
Expression of Human Coagulation Factor VIII in a Human Hybrid Cell Line, HKB11
2006 · Baisong Mei, Yaoqi Chen, et al. · Molecular Biotechnology · 38
Hyperactivity of Human DNase I Variants
1998 · Clark Q. Pan, Robert A. Lazarus · Journal of Biological Chemistry · 38
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Optimizing the Targeted Chemical Nuclease Activity of 1,10-Phenanthroline−Copper by Ligand Modification
1996 · James Gallagher, Chi-hong B. Chen, et al. · Bioconjugate Chemistry · 37
Impact of cysteine variants on the structure, activity, and stability of recombinant human α‐galactosidase A
2015 · Huawei Qiu, Denise M. Honey, et al. · Protein Science · 34
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Identification of New Fis Binding Sites by DNA Scission with Fis-1,10-phenanthroline−Copper(I) Chimeras
1996 · Clark Q. Pan, Reid C. Johnson, et al. · Biochemistry · 30
Engineering Novel VPAC2-Selective Agonists with Improved Stability and Glucose-Lowering Activity in Vivo
2006 · Clark Q. Pan, Fugang Li, et al. · Journal of Pharmacology and Experimental Therapeutics · 28
Ca2+‐dependent activity of human DNase I and its hyperactive variants
1999 · Clark Q. Pan, Robert A. Lazarus · Protein Science · 28
Works count: 52
Citation count: 2,433
H-index: 25
I10-index: 41
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