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Elspeth M. Beauchamp

Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway
2010 · Elspeth M. Beauchamp, Lymor Ringer, et al. · Journal of Clinical Investigation · 351
Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells
2011 · G Bulut, S-H Hong, et al. · Oncogene · 180
GLI1 Is a Direct Transcriptional Target of EWS-FLI1 Oncoprotein
2009 · Elspeth Beauchamp, Gulay Bulut, et al. · Journal of Biological Chemistry · 170
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The evolution of the TOR pathway and its role in cancer
2012 · E M Beauchamp, L C Platanias · Oncogene · 157
Wnt signaling promotes proliferation and stemness regulation of spermatogonial stem/progenitor cells
2009 · Nady Golestaneh, Elspeth Beauchamp, et al. · Reproduction · 142
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YK-4-279 Inhibits ERG and ETV1 Mediated Prostate Cancer Cell Invasion
2011 · Said Rahim, Elspeth M. Beauchamp, et al. · PLoS ONE · 104
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Wnt-3a and Dickkopf-1 Stimulate Neurite Outgrowth in Ewing Tumor Cells via a Frizzled3- and c-Jun N-Terminal Kinase-Dependent Mechanism
2008 · Yoshimi Endo, Elspeth Beauchamp, et al. · Molecular and Cellular Biology · 97
Autophagy Is a Survival Mechanism of Acute Myelogenous Leukemia Precursors during Dual mTORC2/mTORC1 Targeting
2014 · Jessica K. Altman, Amy Szilard, et al. · Clinical Cancer Research · 94
Central Role of ULK1 in Type I Interferon Signaling
2015 · Diana Saleiro, Swarna Mehrotra, et al. · Cell Reports · 76
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Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells
2015 · Antonella Sassano, Evangelos Mavrommatis, et al. · Molecular and Cellular Biology · 60
Beta-Catenin Accelerates Human Papilloma Virus Type-16 Mediated Cervical Carcinogenesis in Transgenic Mice
2011 · Gülay Bulut, Shannon Fallen, et al. · PLoS ONE · 56
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Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo
2016 · Ewa M. Kosciuczuk, Diana Saleiro, et al. · Blood · 50
Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation
2017 · Jonathan B. Bell, Frank Eckerdt, et al. · Molecular Cancer Research · 42
Identification and targeting of novel CDK9 complexes in acute myeloid leukemia
2018 · Elspeth M. Beauchamp, Sameem M. Abedin, et al. · Blood · 39
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Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells
2014 · Frank Eckerdt, Elspeth Beauchamp, et al. · Oncotarget · 38
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Pharmacological mTOR targeting enhances the antineoplastic effects of selective PI3Kα inhibition in medulloblastoma
2019 · Frank Eckerdt, Jessica Clymer, et al. · Scientific Reports · 34
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A New Era for an Ancient Drug
2012 · Elspeth M. Beauchamp, Aykut Üren · Vitamins and hormones · 30
Discovery of a signaling feedback circuit that defines interferon responses in myeloproliferative neoplasms
2022 · Diana Saleiro, Jeremy Q. Wen, et al. · Nature Communications · 27
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Direct Binding of Arsenic Trioxide to AMPK and Generation of Inhibitory Effects on Acute Myeloid Leukemia Precursors
2014 · Elspeth M. Beauchamp, Ewa M. Kosciuczuk, et al. · Molecular Cancer Therapeutics · 27
Schlafen 5 as a novel therapeutic target in pancreatic ductal adenocarcinoma
2021 · Mariafausta Fischietti, Frank Eckerdt, et al. · Oncogene · 23
Potent Antineoplastic Effects of Combined PI3Kα–MNK Inhibition in Medulloblastoma
2019 · Frank Eckerdt, Jonathan B. Bell, et al. · Molecular Cancer Research · 17
Dual targeting of acute myeloid leukemia progenitors by catalytic mTOR inhibition and blockade of the p110α subunit of PI3 kinase
2015 · Marco Colamonici, Gavin Blyth, et al. · Oncotarget · 17
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Resveratrol enhances the suppressive effects of arsenic trioxide on primitive leukemic progenitors
2014 · Edward J Wu, Dennis J Goussetis, et al. · Cancer Biology & Therapy · 17
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SLFN11 Negatively Regulates Noncanonical NFκB Signaling to Promote Glioblastoma Progression
2022 · Mariafausta Fischietti, Frank Eckerdt, et al. · Cancer Research Communications · 14
OTS167 blocks FLT3 translation and synergizes with FLT3 inhibitors in FLT3 mutant acute myeloid leukemia
2021 · Bartholomew J. Eisfelder, Caner Saygin, et al. · Blood Cancer Journal · 14
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Works count: 127
Citation count: 1,947
H-index: 20
I10-index: 29
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