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Holger Rosenbrock

Observed names: H ROSENBROCK, H Rosenbrock, H. Rosenbrock, Rosenbrock, H., Rosenbrock, Holger
Observed institutions: Boehringer Ingelheim (Germany), University of Freiburg, University of Zurich, Boehringer Ingelheim (United States), University of Genoa, Leibniz Institute for Neurobiology
ORCID: 0000-0002-9663-1901
Observed ORCID: 0000-0002-9663-1901
OpenAlex ID: A5077759727
Effect of chronic intermittent restraint stress on hippocampal expression of marker proteins for synaptic plasticity and progenitor cell proliferation in rats
2005 · Holger Rosenbrock, Eliza Koros, et al. · Brain Research · 139
Development of the novel GlyT1 inhibitor, iclepertin (BI 425809), for the treatment of cognitive impairment associated with schizophrenia
2023 · Holger Rosenbrock, Michael Desch, et al. · European Archives of Psychiatry and Clinical Neuroscience · 85
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The Selective mGlu5 Receptor Antagonist MTEP, Similar to NMDA Receptor Antagonists, Induces Social Isolation in Rats
2006 · Eliza Koros, Holger Rosenbrock, et al. · Neuropsychopharmacology · 82
PDE9A inhibition rescues amyloid beta-induced deficits in synaptic plasticity and cognition
2014 · Katja S. Kroker, Chantal Mathis, et al. · Neurobiology of Aging · 69
Preclinical validation of the micropipette-guided drug administration (MDA) method in the maternal immune activation model of neurodevelopmental disorders
2020 · Joseph Scarborough, Flavia Mueller, et al. · Brain Behavior and Immunity · 67
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Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons
2002 · Ilyas Singec, Rolf Knoth, et al. · The Journal of Comparative Neurology · 63
Functional interaction of metabotropic glutamate receptor 5 and NMDA-receptor by a metabotropic glutamate receptor 5 positive allosteric modulator
2010 · Holger Rosenbrock, Gert Kramer, et al. · European Journal of Pharmacology · 62
A comprehensive analysis of auditory event-related potentials and network oscillations in an NMDA receptor antagonist mouse model using a novel wireless recording technology
2018 · Niklas Schuelert, Cornelia Dorner-Ciossek, et al. · Physiological Reports · 61
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Inhibition of acetylcholinesterase and phosphodiesterase-9A has differential effects on hippocampal early and late LTP
2012 · Katja S. Kroker, Georg Rast, et al. · Neuropharmacology · 60
Expression of brain derived neurotrophic factor, activity-regulated cytoskeleton protein mRNA, and enhancement of adult hippocampal neurogenesis in rats after sub-chronic and chronic treatment with the triple monoamine re-uptake inhibitor tesofensine
2006 · Marianne H. Larsen, Holger Rosenbrock, et al. · European Journal of Pharmacology · 46
Predominantly neuronal expression of cytochrome P450 isoforms cyp3a11 and cyp3a13 in mouse brain
2003 · C.E Hagemeyer, H Rosenbrock, et al. · Neuroscience · 46
Reduced cGMP levels in CSF of AD patients correlate with severity of dementia and current depression
2017 · Raphael Hesse, Ludwig Lausser, et al. · Alzheimer s Research & Therapy · 45
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Evaluation of Pharmacokinetics and Pharmacodynamics of BI 425809, a Novel GlyT1 Inhibitor: Translational Studies
2018 · Holger Rosenbrock, Michael Desch, et al. · Clinical and Translational Science · 44
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Sub-chronic rolipram treatment leads to a persistent improvement in long-term object memory in rats
2008 · K. Rutten, J. Prickaerts, et al. · Neurobiology of Learning and Memory · 41
Suppression of Parvalbumin Interneuron Activity in the Prefrontal Cortex Recapitulates Features of Impaired Excitatory/Inhibitory Balance and Sensory Processing in Schizophrenia
2019 · Oana Toader, Moritz von Heimendahl, et al. · Schizophrenia Bulletin · 39
Safety, Tolerability and Pharmacokinetics of Oral BI 425809, a Glycine Transporter 1 Inhibitor, in Healthy Male Volunteers: A Partially Randomised, Single-Blind, Placebo-Controlled, First-in-Human Study
2017 · Viktoria Moschetti, Michael Desch, et al. · European Journal of Drug Metabolism and Pharmacokinetics · 39
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The Novel Phosphodiesterase 9A Inhibitor BI 409306 Increases Cyclic Guanosine Monophosphate Levels in the Brain, Promotes Synaptic Plasticity, and Enhances Memory Function in Rodents
2019 · Holger Rosenbrock, Riccardo Giovannini, et al. · Journal of Pharmacology and Experimental Therapeutics · 38
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Inhibition of PDE2A, but not PDE9A, modulates presynaptic short‐term plasticity measured by paired‐pulse facilitation in the CA1 region of the hippocampus
2015 · Diego Fernández‐Fernández, Holger Rosenbrock, et al. · Synapse · 38
Touchscreen tasks in mice to demonstrate differences between hippocampal and striatal functions
2015 · David F. Delotterie, Chantal Mathis, et al. · Neurobiology of Learning and Memory · 38
Effects of the Glycine Transporter-1 Inhibitor Iclepertin (BI 425809) on Sensory Processing, Neural Network Function, and Cognition in Animal Models Related to Schizophrenia
2022 · Holger Rosenbrock, Cornelia Dorner-Ciossek, et al. · Journal of Pharmacology and Experimental Therapeutics · 34
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Differential effects of subtype-specific nicotinic acetylcholine receptor agonists on early and late hippocampal LTP
2011 · Katja S. Kroker, Georg Rast, et al. · European Journal of Pharmacology · 31
Targeting the dopamine D1 receptor or its downstream signalling by inhibiting phosphodiesterase‐1 improves cognitive performance
2018 · Anton Pekcec, Niklas Schülert, et al. · British Journal of Pharmacology · 29
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Role of PDE9 in Cognition
2017 · C. Dorner-Ciossek, K. S. Kroker, et al. · Advances in neurobiology · 29
Overexpression of Protein Kinase Mζ in the Hippocampus Enhances Long-Term Potentiation and Long-Term Contextual But Not Cued Fear Memory in Rats
2016 · Sven R.M. Schuette, Diego Fernández-Fernández, et al. · Journal of Neuroscience · 28
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Restoring long-term potentiation impaired by amyloid-beta oligomers: Comparison of an acetylcholinesterase inhibitior and selective neuronal nicotinic receptor agonists
2013 · Katja S. Kroker, Jens Moreth, et al. · Brain Research Bulletin · 24
Works count: 104
Citation count: 1,643
H-index: 24
I10-index: 43
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