Get started
Author

Víctor M. Castillo‐Acosta

Observed names: Castillo Acosta, Víctor M., Castillo Acosta, Víctor M.;, Castillo-Acosta, Víctor, Castillo-Acosta, Víctor M, Castillo-Acosta, Víctor M., V. Castillo-Acosta, V. M. Castillo-Acosta, V.M. Castillo-Acosta, VM Castillo-Acosta, Victor M. Castillo-Acosta, Victor Manuel Castillo-Acosta, Victor Manuel Castillo-acosta, Víctor Castillo-Acosta, Víctor M. Castillo Acosta, Víctor M. Castillo-Acosta
ORCID: 0000-0003-0938-2343
Observed ORCID: 0000-0003-0938-2343
OpenAlex ID: A5078464342
Intracellular location of the early steps of the isoprenoid biosynthetic pathway in the trypanosomatids Leishmania major and Trypanosoma brucei
2008 · Juana Carrero-Lérida, Guiomar Pérez-Moreno, et al. · International Journal for Parasitology · 43
Depletion of dimeric all-α dUTPase induces DNA strand breaks and impairs cell cycle progression in Trypanosoma brucei
2008 · Víctor M. Castillo-Acosta, Antonio M. Estévez, et al. · The International Journal of Biochemistry & Cell Biology · 42
New Azasterols against Trypanosoma brucei : Role of 24-Sterol Methyltransferase in Inhibitor Action
2006 · Ludovic Gros, Victor Manuel Castillo-Acosta, et al. · Antimicrobial Agents and Chemotherapy · 42
Increased uracil insertion in DNA is cytotoxic and increases the frequency of mutation, double strand break formation and VSG switching in Trypanosoma brucei
2012 · Víctor M. Castillo-Acosta, Fernando Aguilar-Pereyra, et al. · DNA repair · 28
Identification of a residue critical for the excision of 3'-blocking ends in apurinic/apyrimidinic endonucleases of the Xth family
2009 · V. M. Castillo-Acosta, L. M. Ruiz-Perez, et al. · Nucleic Acids Research · 26
PDF
Crystal Structure and DNA Repair Activities of the AP Endonuclease from Leishmania major
2007 · Antonio E. Vidal, Maria Harkiolaki, et al. · Journal of Molecular Biology · 26
Endogenous sterol biosynthesis is important for mitochondrial function and cell morphology in procyclic forms of Trypanosoma brucei
2012 · Guiomar Pérez-Moreno, Marco Sealey-Cardona, et al. · International Journal for Parasitology · 25
Pyrimidine requirements in deoxyuridine triphosphate nucleotidohydrolase deficient Trypanosoma brucei mutants
2012 · Víctor M. Castillo-Acosta, Fernando Aguilar-Pereyra, et al. · Molecular and Biochemical Parasitology · 21
Trypanosomes lacking uracil-DNA glycosylase are hypersensitive to antifolates and present a mutator phenotype
2012 · Víctor M. Castillo-Acosta, Fernando Aguilar-Pereyra, et al. · The International Journal of Biochemistry & Cell Biology · 21
Carbohydrate-Binding Non-Peptidic Pradimicins for the Treatment of Acute Sleeping Sickness in Murine Models
2016 · Víctor M. Castillo-Acosta, Luis M. Ruiz-Pérez, et al. · PLoS Pathogens · 17
PDF
Cell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma brucei
2016 · Maria Valente, Jennifer Timm, et al. · Molecular Microbiology · 16
PDF
Trypanosoma brucei AP endonuclease 1 has a major role in the repair of abasic sites and protection against DNA-damaging agents
2011 · Karen S. Charret, Cristina E. Requena, et al. · DNA repair · 15
PDF
Exposure of Trypanosoma brucei to an N-acetylglucosamine-Binding Lectin Induces VSG Switching and Glycosylation Defects Resulting in Reduced Infectivity
2015 · Víctor M. Castillo-Acosta, Luis M. Ruiz-Pérez, et al. · PLoS neglected tropical diseases · 14
PDF
Overview of the role of kinetoplastid surface carbohydrates in infection and host cell invasion: prospects for therapeutic intervention
2019 · Maria Valente, Víctor M. Castillo-Acosta, et al. · Parasitology · 12
PDF
Carbohydrate‐binding agents act as potent trypanocidals that elicit modifications in VSG glycosylation and reduced virulence in T rypanosoma brucei
2013 · Víctor M. Castillo‐Acosta, Antonio E. Vidal, et al. · Molecular Microbiology · 12
PDF
A Mitochondrial Orthologue of the dNTP Triphosphohydrolase SAMHD1 Is Essential and Controls Pyrimidine Homeostasis in Trypanosoma brucei
2021 · Miriam Yagüe-Capilla, Víctor M. Castillo-Acosta, et al. · ACS Infectious Diseases · 11
In vitro antiplasmodial and cytotoxic activities of asymmetrical pyridinium derivatives
2014 · Belén Rubio-Ruiz, Víctor M. Castillo-Acosta, et al. · European Journal of Medicinal Chemistry · 10
Contribution of Cytidine Deaminase to Thymidylate Biosynthesis in Trypanosoma brucei: Intracellular Localization and Properties of the Enzyme
2019 · Ana Moro-Bulnes, Víctor M. Castillo-Acosta, et al. · mSphere · 9
Base excision repair plays an important role in the protection against nitric oxide- and in vivo-induced DNA damage in Trypanosoma brucei
2018 · Miriam Yagüe-Capilla, Daniel García-Caballero, et al. · Free Radical Biology and Medicine · 7
A nuclear orthologue of the dNTP triphosphohydrolase SAMHD1 controls dNTP homeostasis and genomic stability in Trypanosoma brucei
2023 · Pablo Antequera-Parrilla, Víctor M. Castillo-Acosta, et al. · Frontiers in Cellular and Infection Microbiology · 5
Surface Glycans: A Therapeutic Opportunity for Kinetoplastid Diseases
2017 · Víctor M. Castillo-Acosta, Jan Balzarini, et al. · Trends in Parasitology · 5
Identification of SAMHD1 orthologues in Trypanosoma brucei reveals novel features of pyrimidine dNTP homeostasis
2020 · M Yagüe Capilla, VM Castillo-Acosta, et al.
Control of nucleotide homeostasis and genomic integrity in Trypanosoma brucei: role of HD nucleotidases and base excision repair
2020 · Víctor M. Castillo Acosta, Dolores González‐Pacanowska, et al. · Dialnet (Universidad de la Rioja)
Deciphering the role of HD52, a mitochondrial nucleotidase essential for pyrimidine homeostasis in Trypanosoma brucei
2019 · Miriam Yagüe-Capilla, VM Castillo-Acosta, et al. · DIGITAL.CSIC (Spanish National Research Council (CSIC))
PDF
Essentiality and role of novel nucleotidases involved in Trypanosoma brucei pyrimidine homeostasis
2019 · M Yagüe Capilla, Víctor M. Castillo Acosta, et al.
Works count: 47
Citation count: 407
H-index: 13
I10-index: 17
Year
Topic
Type