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Douglas Wisniewski

Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy
2017 · Robert W. Myers, Hong-Ping Guan, et al. · Science · 346
Crystal Structure of Inhibitor-Bound Human 5-Lipoxygenase-Activating Protein
2007 · Andrew D. Ferguson, Brian M. McKeever, et al. · Science · 227
Anthrax lethal factor inhibition
2005 · W. L. Shoop, Y. Xiong, et al. · Proceedings of the National Academy of Sciences · 172
A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo1[S]
2010 · Yan G. Ni, Stefania Di Marco, et al. · Journal of Lipid Research · 135
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In vitro studies evaluating the activity of imipenem in combination with relebactam against Pseudomonas aeruginosa
2019 · Katherine Young, Ronald E. Painter, et al. · BMC Microbiology · 126
A Proprotein Convertase Subtilisin-like/Kexin Type 9 (PCSK9) C-terminal Domain Antibody Antigen-binding Fragment Inhibits PCSK9 Internalization and Restores Low Density Lipoprotein Uptake
2010 · Yan G. Ni, Jon H. Condra, et al. · Journal of Biological Chemistry · 107
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The nuclear membrane organization of leukotriene synthesis
2008 · Asim K. Mandal, Phillip B. Jones, et al. · Proceedings of the National Academy of Sciences · 102
An Anti-PCSK9 Antibody Reduces LDL-Cholesterol On Top Of A Statin And Suppresses Hepatocyte SREBP-Regulated Genes
2012 · Liwen Zhang, Timothy McCabe, et al. · International Journal of Biological Sciences · 101
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A peptide-based fluorescence resonance energy transfer assay for Bacillus anthracis lethal factor protease
2002 · Richard T. Cummings, Scott P. Salowe, et al. · Proceedings of the National Academy of Sciences · 96
The membrane organization of leukotriene synthesis
2004 · Asim K. Mandal, Jesse Skoch, et al. · Proceedings of the National Academy of Sciences · 93
PAP Inhibitor with In Vivo Efficacy Identified by Candida albicans Genetic Profiling of Natural Products
2008 · Bo Jiang, Deming Xu, et al. · Chemistry & Biology · 82
Elucidation of DnaE as the Antibacterial Target of the Natural Product, Nargenicin
2015 · Ronald E. Painter, Gregory C. Adam, et al. · Chemistry & Biology · 39
Cell-Based Assays to Detect Inhibitors of Fungal mRNA Capping Enzymes and Characterization of Sinefungin as a Cap Methyltransferase Inhibitor
2005 · Gary L. Chrebet, Douglas Wisniewski, et al. · SLAS DISCOVERY · 30
Application of Affinity Selection/Mass Spectrometry to Determine the Structural Isomer of Parnafungins Responsible for Binding Polyadenosine Polymerase
2008 · Gregory C. Adam, Craig A. Parish, et al. · Journal of the American Chemical Society · 27
Time-resolved Forster resonance energy transfer assays for the binding of nucleotide and protein substrates to p38α protein kinase
2005 · Wen Xiao Zhang, Ruixiu Wang, et al. · Analytical Biochemistry · 22
Assay for IκB Kinases Using an in Vivo Biotinylated IκB Protein Substrate
1999 · D. Wisniewski, P. LoGrasso, et al. · Analytical Biochemistry · 22
Variable subcellular localization of a neuron-specific protein during NTera 2 differentiation into post-mitotic human neurons
1996 · Leon Carlock, Trieu Vo, et al. · Molecular Brain Research · 14
Expression, purification and crystallization of human 5-lipoxygenase-activating protein with leukotriene-biosynthesis inhibitors
2007 · Shihua Xu, Brian M. McKeever, et al. · Acta Crystallographica Section F Structural Biology and Crystallization Communications · 8
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Thiophenyl oxime-derived phosphonates as nano-molar class C beta-lactamase inhibitors reducing MIC of imipenem against Pseudomonas aeruginosa and Acinetobacter baumannii
2011 · Qiang Tan, Aimie M. Ogawa, et al. · Bioorganic & Medicinal Chemistry Letters · 7
An estimate of the number of genes in the huntington disease gene region and the identification of 13 transcripts in the 4p 16.3 segment
1992 · L. Carlock, D. Wisniewski, et al. · Genomics · 7
Abstract 1317: A Proprotein Convertase Subtilisin-like/Kexin Type 9 (PCSK9)-binding Antibody, That Structurally Mimics the Egf-a Domain of the LDL-receptor, Lowers LDL-cholesterol in a Transgenic Mouse Model and in Rhesus Monkeys
2009 · Jon H. Condra, Andrea Carfı́, et al. · Circulation · 2
Abstract 1318: A PCSK9 C-terminal Domain Binding Fab Inhibits PCSK9 Internalization and Restores LDL-uptake
2009 · Ni Yan, Jon H. Condra, et al. · Circulation
Abstract 831: Functional Analysis of S127 and D374 Residues of PCSK9: Distinct Hot Spots for Gain of Function
2007 · Timothy S Fisher, Shilpa Pandit, et al. · Circulation
Works count: 29
Citation count: 1,765
H-index: 16
I10-index: 17
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