Author

Jesse R. Pascual

Observed names: Jesse Pascual, Jesse R Pascual

Institution: University of California, Irvine

Observed institution: University of California, Irvine

ORCID: 0000-0002-3307-0887

Observed ORCID: 0000-0002-3307-0887

OpenAlex ID: A5080952890

Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice

2022 · Sepideh Kiani Shabestari, Samuel Morabito, et al. · Cell Reports · 166

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Lecanemab and Vascular-Amyloid Deposition in Brains of People With Down Syndrome

2024 · Lei Liu, Adriana Saba, et al. · JAMA Neurology · 26

Regional differences in astrocytic Aquaporin-4 protein levels and distribution in aging and Alzheimer's disease in down syndrome

2025 · Cherie A. Stringer, Haley K.S. Miyasato, et al. · Neurobiology of Disease · 8

A Trisomy 21-linked Hematopoietic Gene Variant in Microglia Confers Resilience in Human iPSC Models of Alzheimer’s Disease

2024 · Mengmeng Jin, Ziyuan Ma, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 5

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Leptin levels are associated with body mass index and Alzheimer's disease in Down syndrome

2025 · Lorena Sordo, Annie Du, et al. · Alzheimer s & Dementia · 4

Age and sex are associated with Alzheimer's disease neuropathology in Down syndrome

2025 · Elizabeth J. Andrews, Phong T. Ngo, et al. · Alzheimer s & Dementia · 4

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A myeloid trisomy 21-associated gene variant is protective from Alzheimer’s disease

2025 · Mengmeng Jin, Ziyuan Ma, et al. · Nature Neuroscience · 1

Neuropathology of trisomy 21 mosaicism in a case with early‐onset dementia

2024 · Phong T. Ngo, Jesse R. Pascual, et al. · Alzheimer s & Dementia · 1

Investigating the Role of Estrogen Receptor Alpha in Alzheimer’s Disease Pathogenesis in Down Syndrome

2023 · Elizabeth J. Andrews, Michael J. Phelan, et al. · Alzheimer s & Dementia · 1

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Neuropathological measures of increased tau phosphorylation across the Down syndrome lifespan

2026 · Jesse R. Pascual, Isabel Rivera, et al. · Acta Neuropathologica

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Blood‐brain barrier integrity and vessel morphology in adults with Down syndrome and Alzheimer's neuropathology

2025 · Lisi Flores Aguilar, Jesse R. Pascual, et al. · Alzheimer s & Dementia

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Women with Down syndrome show more severe Alzheimer's disease neuropathology with regional differences

2025 · Elizabeth J. Andrews, Phong T. Ngo, et al. · Alzheimer s & Dementia

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Histofluorescence analysis of Pittsburgh Compound B labeled pathology in Down syndrome putamen and frontal cortex

2024 · Jeremy P. Rouanet, Kim Chan Ngo, et al. · Alzheimer s & Dementia

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Age and Sex Impact Alzheimer’s Disease‐associated Plaques and Tangles in Down Syndrome

2024 · Elizabeth J. Andrews, Michael J. Phelan, et al. · Alzheimer s & Dementia

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Neuropathological characterization of PiB binding in postmortem striatum in Down syndrome

2023 · Jeremy P. Rouanet, Tamara Shamas, et al. · Alzheimer s & Dementia

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Phosphorylated tau in the Down syndrome brain: Age related increases and comparison to late‐onset Alzheimer’s Disease

2023 · Jesse R. Pascual, Halyma Nguyen, et al. · Alzheimer s & Dementia

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2023 · Sepideh Kiani Shabestari, Hamsi Radhakrishnan, et al. · Alzheimer s & Dementia

Works count: 17

Citation count: 216

H-index: 4

I10-index: 2