Get started
Author

Jay F. Davies

Observed names: J F Davies, J. F. II DAVIES, J.F. Davies, J.F. Davies II, Jay Davies
OpenAlex ID: A5081850520
Viracept (Nelfinavir Mesylate, AG1343): A Potent, Orally Bioavailable Inhibitor of HIV-1 Protease
1997 · Stephen W. Kaldor, Vincent J. Kalish, et al. · Journal of Medicinal Chemistry · 618
Crystal Structure of the Ribonuclease H Domain of HIV-1 Reverse Transcriptase
1991 · Jay F. Davies, Zuzana Hostomska, et al. · Science · 571
Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19
2020 · Robert L. Hoffman, Robert S. Kania, et al. · Journal of Medicinal Chemistry · 533
PDF
Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate
1990 · Jay F. Davies, Tavner J. Delcamp, et al. · Biochemistry · 175
2.3 Å crystal structure of the catalytic domain of DNA polymerase β
1994 · Jay F. Davies, Robert J. Almassy, et al. · Cell · 168
Dihydroxyphenylisoindoline Amides as Orally Bioavailable Inhibitors of the Heat Shock Protein 90 (Hsp90) Molecular Chaperone
2009 · Pei-Pei Kung, Buwen Huang, et al. · Journal of Medicinal Chemistry · 75
Crystal structure of chicken liver dihydrofolate reductase complexed with NADP+ and biopterin
1992 · Michele A. McTigue, Jay F. Davies, et al. · Biochemistry · 68
Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone
2008 · Pei-Pei Kung, Lee Funk, et al. · Bioorganic & Medicinal Chemistry Letters · 54
Protein structure-based design of potent orally bioavailable, nonpeptide inhibitors of human immunodeficiency virus protease.
1995 · S H Reich, M Melnick, et al. · Proceedings of the National Academy of Sciences · 50
Structure-Based Design and Synthesis of Substituted 2-Butanols as Nonpeptidic Inhibitors of HIV Protease: Secondary Amide Series
1996 · Siegfried H. Reich, Michael Melnick, et al. · Journal of Medicinal Chemistry · 41
Structure and Functional Relationships in Human pur H
1998 · G. Peter Beardsley, Elizabeth A. Rayl, et al. · Advances in experimental medicine and biology · 34
Proteolytic release and crystallization of the RNase H domain of human immunodeficiency virus type 1 reverse transcriptase
1991 · Z. Hostomska, D.A. Matthews, et al. · Journal of Biological Chemistry · 34
Bis Tertiary Amide Inhibitors of the HIV-1 Protease Generated via Protein Structure-Based Iterative Design
1996 · Michael Melnick, Siegfried H. Reich, et al. · Journal of Medicinal Chemistry · 31
Structure-based drug design of nonpeptidic P2 substituents for HIV-1 protease inhibitors
1995 · Vincent J. Kalish, John H. Tatlock, et al. · Bioorganic & Medicinal Chemistry Letters · 24
Crystal structures of chicken liver dihydrofolate reductase: Binary thioNADP+ and ternary thioNADP+.cntdot.biopterin complexes
1993 · Michele A. McTigue, Jay F. Davies, et al. · Biochemistry · 24
Iterative Protein Structure-based Drug Design and Synthesis of Hiv Protease Inhibitors
1995 · Vincent Kalish, Stephen Kaldor, et al. · European Journal of Medicinal Chemistry · 23
Three-dimensional structure of the RNase H domain of HIV-1 reverse transcriptase at 2. 4 Å resolution
1992 · David A. Matthews, Jay F. Davies, et al. · Springer eBooks · 2
ChemInform Abstract: Bis Tertiary Amide Inhibitors of the HIV‐1 Protease Generated via Protein Structure‐Based Iterative Design.
1996 · M. MELNICK, S. H. REICH, et al. · ChemInform · 1
ChemInform Abstract: Structure‐Based Design and Synthesis of Substituted 2‐Butanols as Nonpeptidic Inhibitors of HIV Protease: Secondary Amide Series.
1996 · S. H. REICH, M. MELNICK, et al. · ChemInform · 1
HSP90 N-terminal domain in complex with 4-(1,3-dihydro-2H-isoindol-2-ylcarbonyl)benzene-1,3-diol
2009 · K.S. Gajiwala, J.F. Davies II · Worldwide Protein Data Bank
Design, synthesis and evaluation of novel 6-arylsulfonylamino-3-chlorobenzo thiophene-2-carboxyamides Potent, lipophilic inhibitors of 5-aminoimidazole-4-carboxamide ribonucleotide transformylase
1999 · John H. Tatlock, Maria Angelica Linton, et al. · Abstracts of papers - American Chemical Society
ChemInform Abstract: Structure‐Based Drug Design of Nonpeptidic P2 Substituents for HIV‐1 Protease Inhibitors.
1995 · V. J. KALISH, J. H. TATLOCK, et al. · ChemInform
Works count: 23
Citation count: 2,527
H-index: 16
I10-index: 16
Year
Topic
Type