Author

Elena Miranda

Observed names: E Miranda, E. Miranda, Miranda, Miranda, E, Miranda, Elena

Institution: Sapienza University of Rome

Observed institutions: Institut Pasteur, Malmö University, Lund University, University of Cambridge, University Medical Center Hamburg-Eppendorf, Istituto Pasteur, University College London, Instituto Politécnico Nacional, Universidad de Málaga, Sapienza University of Rome, Wellcome Trust, University of Gothenburg

ORCID: 0000-0002-0586-8795

Observed ORCID: 0000-0002-0586-8795

OpenAlex ID: A5082063678

Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

2011 · Kosuke Yusa, S. Tamir Rashid, et al. · Nature · 639

Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells

2010 · S. Tamir Rashid, Sebastien Corbineau, et al. · Journal of Clinical Investigation · 606

Endoplasmic reticulum dysfunction in neurological disease

2012 · Benoit D Roussel, Antonina J Kruppa, et al. · The Lancet Neurology · 441

Intraneuronal Aβ, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer’s disease

2005 · D.C. Crowther, K.J. Kinghorn, et al. · Neuroscience · 351

A Novel Monoclonal Antibody to Characterize Pathogenic Polymers in Liver Disease Associated with α1-Antitrypsin Deficiency†

2010 · Elena Miranda, Juan Pérez, et al. · Hepatology · 158

Endoplasmic Reticulum-associated Degradation (ERAD) and Autophagy Cooperate to Degrade Polymerogenic Mutant Serpins

2009 · Heike Kroeger, Elena Miranda, et al. · Journal of Biological Chemistry · 142

Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1-antitrypsin deficiency

2012 · Adriana Ordóñez, Erik L. Snapp, et al. · Hepatology · 137

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Defining the mechanism of polymerization in the serpinopathies

2010 · Ugo I. Ekeowa, Joanna Freeke, et al. · Proceedings of the National Academy of Sciences · 136

Neuroserpin: a serpin to think about

2006 · E. Miranda, D. A. Lomas · Cellular and Molecular Life Sciences · 127

Plasma and CSF serpins in Alzheimer disease and dementia with Lewy bodies

2007 · H. M. Nielsen, L. Minthon, et al. · Neurology · 119

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Mutants of Neuroserpin That Cause Dementia Accumulate as Polymers within the Endoplasmic Reticulum

2004 · Elena Miranda, Karin Römisch, et al. · Journal of Biological Chemistry · 109

The intracellular accumulation of polymeric neuroserpin explains the severity of the dementia FENIB

2008 · E. Miranda, I. MacLeod, et al. · Human Molecular Genetics · 95

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B‐type Eph receptors and ephrins induce growth cone collapse through distinct intracellular pathways

2003 · Fanny Mann, Elena Miranda, et al. · Journal of Neurobiology · 91

Circulating polymers in α 1 -antitrypsin deficiency

2014 · Lu Tan, Jennifer A. Dickens, et al. · European Respiratory Journal · 85

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Physiological modulation of BiP activity by trans-protomer engagement of the interdomain linker

2015 · Steffen Preissler, Joseph E Chambers, et al. · eLife · 75

Neuroserpin Polymers Activate NF-κB by a Calcium Signaling Pathway That Is Independent of the Unfolded Protein Response

2009 · Mark J. Davies, Elena Miranda, et al. · Journal of Biological Chemistry · 71

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Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies

2003 · Damian C Crowther, Didier Belorgey, et al. · European Journal of Human Genetics · 71

ANCA-associated vasculitis is linked to carriage of the Z allele of α1 antitrypsin and its polymers

2011 · H Morris, M D Morgan, et al. · Annals of the Rheumatic Diseases · 69

Molecular mousetraps and the serpinopathies

2005 · D.A. Lomas, D. Belorgey, et al. · Biochemical Society Transactions · 57

α1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies

2009 · Ugo I. Ekeowa, Bibek Gooptu, et al. · Clinical Science · 54

The structural basis for Z α 1 -antitrypsin polymerization in the liver

2020 · Sarah V. Faull, Emma L. K. Elliston, et al. · Science Advances · 49

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A single‐chain variable fragment intrabody prevents intracellular polymerization of Z α 1 ‐antitrypsin while allowing its antiproteinase activity

2015 · Adriana Ordóñez, Juan Pérez, et al. · The FASEB Journal · 49

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Three New Alpha1-Antitrypsin Deficiency Variants Help to Define a C-Terminal Region Regulating Conformational Change and Polymerization

2012 · Anna M. Fra, Bibek Gooptu, et al. · PLoS ONE · 49

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Neuroserpin: structure, function, physiology and pathology

2021 · Emanuela D’Acunto, Annamaria Fra, et al. · Cellular and Molecular Life Sciences · 46

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Polymers of Z α1-antitrypsin are secreted in cell models of disease

2016 · Annamaria Fra, Francesca Cosmi, et al. · European Respiratory Journal · 45

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Works count: 107

Citation count: 4,886

H-index: 32

I10-index: 67