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Erald Shehu

Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders
2020 · Benjamin R. Bellenie, Kwai-Ming J. Cheung, et al. · Journal of Medicinal Chemistry · 74
Anterior gradient 2 and 3 – two prototype androgen‐responsive genes transcriptionally upregulated by androgens and by oestrogens in prostate cancer cells
2013 · Huajie Bu, Michal R. Schweiger, et al. · FEBS Journal · 52
C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays
2019 · Yann-Vaï Le Bihan, Rachel M. Lanigan, et al. · European Journal of Medicinal Chemistry · 19
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Differences in wild-type– and R338L-tenase complex formation are at the root of R338L-factor IX assay discrepancies
2022 · Jonathan H. Foley, Erald Shehu, et al. · Blood Advances · 16
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FLT201, a novel liver-directed AAV gene therapy candidate for Gaucher disease type 1
2025 · Fabrizio Comper, Carlos J. Miranda, et al. · Molecular Therapy · 10
Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays
2022 · Olivier A. Pierrat, Manjuan Liu, et al. · Scientific Reports · 8
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Investigating the phosphinic acid tripeptide mimetic DG013A as a tool compound inhibitor of the M1-aminopeptidase ERAP1
2021 · Birgit Wilding, A. Elisa Pasqua, et al. · Bioorganic & Medicinal Chemistry Letters · 8
FLT201: An AAV-mediated gene therapy for type 1 Gaucher disease designed to target difficult to reach tissues
2021 · Romuald Corbau, Carlos Miranda, et al. · Molecular Genetics and Metabolism · 3
Generation of β-Glucocerebrosidase variants with increased half-life in human plasma for liver directed AAV gene therapy aimed at the treatment of Gaucher disease type 1
2021 · Fabrizio Comper, I-Mei Yu, et al. · Molecular Genetics and Metabolism · 2
Development of a GLA nAb assay with a fully-human, neutralizing IgG4 positive control to characterize antibody response in Fabry disease patients
2021 · Sujata Ravi, Erald Shehu, et al. · Molecular Genetics and Metabolism
Protein engineering in FLT210, a Potent Next Generation AAV-hFVIII Vector Candidate
2020 · Dodev, Tihomir, Kalcheva, Petya, et al. · HAL
Design and Characterization of FLT210, a Potent Next Generation AAV-hFVIII Vector Candidate
2019 · Azadeh Kia, Fabrizio Comper, et al. · Blood
The expression and function of human Anterior Gradient Homolog 3 in Prostate Cancer
2013 · Shehu, Erald · Repository KITopen (Karlsruhe Institute of Technology)
Works count: 13
Citation count: 192
H-index: 7
I10-index: 5
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