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Inder Bhamra
Observed name:
I. Bhamra
Observed institutions:
University of Liverpool,
Albertus Magnus College,
GlaxoSmithKline (United Kingdom),
Redx Pharma (United Kingdom),
GlaxoSmithKline Research & Development Limited (United Kingdom)
OpenAlex ID:
A5082399428
N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of Lck: Indazoles as phenol isosteres with improved pharmacokinetics
2007
·
Paul Bamborough
, Richard M. Angell
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
50
The Wnt Pathway Inhibitor RXC004 Blocks Tumor Growth and Reverses Immune Evasion in Wnt Ligand–dependent Cancer Models
2022
·
Caroline Phillips
, Inder Bhamra
, et al.
·
Cancer Research Communications
·
40
Base-pairing preferences, physicochemical properties and mutational behaviour of the DNA lesion 8-nitroguanine †
2012
·
Inder Bhamra
, Patricia Compagnone-Post
, et al.
·
Nucleic Acids Research
·
23
PDF
Abstract 506: Wnt/â-Catenin pathway inhibitor RXC004 enhances the immunity of pre-clinical models of cancer
2019
·
Caroline Phillips
, Inder Bhamra
, et al.
·
Cancer Research
·
11
α-Lithio quinuclidine N-oxide (Li-QNO): A new base for synthetic chemistry
2006
·
Ian A. O'Neil
, Inder Bhamra
, et al.
·
Chemical Communications
·
11
Novel porcupine (PORCN) inhibitor RXC004: Evaluation in models of RNF43 loss of function cancers.
2017
·
Inder Bhamra
, Nick Adams
, et al.
·
Journal of Clinical Oncology
·
10
Abstract 3764: Porcupine inhibitor RXC004 enhances immune response in pre-clinical models of cancer
2018
·
Inder Bhamra
, Richard Armer
, et al.
·
Cancer Research
·
9
Artemisinin–Polypyrrole Conjugates: Synthesis, DNA Binding Studies and Preliminary Antiproliferative Evaluation
2013
·
Louise La Pensée
, Sunil Sabbani
, et al.
·
ChemMedChem
·
8
Preclinical data using a novel porcupine inhibitor demonstrates that inhibition of porcupine is a promising target for the treatment of Idiopathic Pulmonary Fibrosis
2019
·
Peter Bunyard
, Inder Bhamra
, et al.
·
European Respiratory Journal
·
5
Abstract 3874: Efficacy of the Wnt/Beta-Catenin pathway inhibitor RXC004 in genetically-defined models of cancer
2019
·
Simon Woodcock
, Inder Bhamra
, et al.
·
Cancer Research
·
5
Stabilization of a Bimolecular Triplex by 3′‐S‐Phosphorothiolate Modifications: An NMR and UV Thermal Melting Investigation
2015
·
Kathryn Evans
, Inder Bhamra
, et al.
·
Chemistry - A European Journal
·
3
Abstract 2566: Pre-clinical efficacy of the Wnt pathway inhibitor RXC004 in combination with anti-cancer therapies
2022
·
James Kelly
, Simon Woodcock
, et al.
·
Cancer Research
·
2
Abstract 998: Mechanism of action of RXC004, a Wnt pathway inhibitor, in genetically-defined models of cancer
2021
·
Caroline Phillips
, Simon Woodcock
, et al.
·
Cancer Research
·
2
The synthesis of functionalised peptides using α-lithio quinuclidine N-oxide (Li-QNO)
2009
·
Ian A. O’Neil
, Inder Bhamra
·
Tetrahedron Letters
·
2
Directed lithiation on the quinuclidine ring system: the synthesis of 2,3-difunctionalised quinuclidines
2008
·
Ian A. O’Neil
, James Hitchin
, et al.
·
Tetrahedron Letters
·
2
Abstract 944: Pre-clinical activity of the Wnt pathway inhibitor RXC004 in combination with MAPK pathway inhibitors in GI cancer models
2024
·
Simon A. Woodcock
, Dorottya Keppel
, et al.
·
Cancer Research
·
1
Identification of an RNF43 mutated gastric cancer patient population with potential sensitivity to porcupine inhibitor RXC004 and development of a complimentary ctDNA liquid biopsy assay for patient screening
2017
·
M. Bingham
, I. Bhamra
, et al.
·
Annals of Oncology
·
1
PDF
Novel Porcupine inhibitor RXC004: Potent efficacy in animal models of cancer through direct tumour targeting and immunomodulatory mechanisms
2016
·
I. Bhamra
, V. Abet
, et al.
·
European Journal of Cancer
·
1
Inside Cover: Artemisinin–Polypyrrole Conjugates: Synthesis, DNA Binding Studies and Preliminary Antiproliferative Evaluation (ChemMedChem 5/2013)
2013
·
Louise La Pensée
, Sunil Sabbani
, et al.
·
ChemMedChem
·
1
PDF
Abstract A101: Novel KRAS inhibitors suppress MAPK pathway signalling and display potent anti-proliferative activity across a broad range of KRAS mutant cell lines
2023
·
Inder Bhamra
, Helen Mason
, et al.
·
Molecular Cancer Therapeutics
Development of Novel Selective DDR1 Inhibitors with the Potential to Treat CKD
2023
·
Nicolas E. Guisot
, Daniel J. Wilcock
, et al.
·
Journal of the American Society of Nephrology
Data from The Wnt Pathway Inhibitor RXC004 Blocks Tumor Growth and Reverses Immune Evasion in Wnt Ligand–dependent Cancer Models
2023
·
Caroline Phillips
, Inder Bhamra
, et al.
Supplementary Figures 1-7, Table 1 from The Wnt Pathway Inhibitor RXC004 Blocks Tumor Growth and Reverses Immune Evasion in Wnt Ligand–dependent Cancer Models
2023
·
Caroline Phillips
, Inder Bhamra
, et al.
Abstract 1654: Pre-clinical activity of the Wnt/Beta-catenin pathway inhibitor RXC004 in models of biliary tract cancer
2023
·
Simon A. Woodcock
, Dorottya Keppel
, et al.
·
Cancer Research
Data from The Wnt Pathway Inhibitor RXC004 Blocks Tumor Growth and Reverses Immune Evasion in Wnt Ligand–dependent Cancer Models
2023
·
Caroline Phillips
, Inder Bhamra
, et al.
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Works count:
29
Citation count:
187
H-index:
8
I10-index:
6
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