Get started
Author

Giang N. Nguyen

Observed names: G.N. Nguyen, Giang N Nguyen
ORCID: 0000-0003-3205-9106
Observed ORCID: 0000-0003-3205-9106
OpenAlex ID: A5083116189
A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells
2020 · Giang N. Nguyen, John K. Everett, et al. · Nature Biotechnology · 426
Functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing
2020 · Xinfu Zhang, Weiyu Zhao, et al. · Science Advances · 182
Overexpression of factor VIII after AAV delivery is transiently associated with cellular stress in hemophilia A mice
2016 · Amy M Lange, Ekaterina S Altynova, et al. · Molecular Therapy — Methods & Clinical Development · 78
Novel factor VIII variants with a modified furin cleavage site improve the efficacy of gene therapy for hemophilia A
2016 · G.N. Nguyen, L.A. George, et al. · Journal of Thrombosis and Haemostasis · 50
Long-Term AAV-Mediated Factor VIII Expression in Nine Hemophilia A Dogs: A 10 Year Follow-up Analysis on Durability, Safety and Vector Integration
2019 · Giang N. Nguyen, John K. Everett, et al. · Blood · 27
Preclinical assessment of an optimized AAV-FVIII vector in mice and non-human primates for the treatment of hemophilia A
2021 · Liron Elkouby, Sean M. Armour, et al. · Molecular Therapy — Methods & Clinical Development · 17
PDF
Altered cleavage of human factor VIII at the B-domain and acidic region 3 interface enhances expression after gene therapy in hemophilia A mice
2023 · Giang N. Nguyen, Jonathan R. Lindgren, et al. · Journal of Thrombosis and Haemostasis · 8
PDF
Sustained Factor VIII Activity Following Single Dose of Non-Viral Integrating Gene Therapy
2022 · Brian Truong, Giang N. Nguyen, et al. · Blood · 3
Hemophilia A Dogs Tolerant to Human Factor VIII Provide a Unique Model to Determine Efficacy and Safety of AAV Delivery of Novel Factor VIII Variants
2019 · Giang N. Nguyen, Lauren E. Wimsey, et al. · Blood · 2
Second Generation Adeno-Associated Viral Vector Using a Novel Factor VIII Variant with Improved Secretion Achieves Higher Factor VIII Expression in Non-Human Primates
2022 · Giang N. Nguyen, Maria C. Seleme, et al. · Blood · 1
Generation of a Unique Cohort of Hemophilia A Dogs Tolerant to Human FVIII for Evaluating the Safety and Efficacy of AAV Delivery of Wild Type and Variant Human FVIII
2018 · Giang N. Nguyen, Lauren Wimsey, et al. · Blood
Novel Human Factor VIII Variant with Impaired Intracellular Processing Exhibits Enhanced In Vivo Efficacy
2016 · Giang N. Nguyen, Christian M. Wood, et al. · Blood
Human Factor VIII Variants with Diminished PACE-Furin Cleavage Exhibit Increased Biological Activity and Therapeutic Efficacy
2014 · Giang N. Nguyen, Joshua I. Siner, et al. · Blood
Works count: 13
Citation count: 794
H-index: 7
I10-index: 6
Year
Topic
Type