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David M. Stresser

Observed names: D M Stresser, D. M. Stresser, D.M. Stresser, DAVID M. STRESSER, David M. Stresser, David M Stresser, David Stresser, Stresser, David M.
Observed institutions: Foundation for Biomedical Research, Oregon State University, Corning (United States), University of Massachusetts Chan Medical School, AbbVie (United States), BD Biosciences (United States), UMass Memorial Medical Center, Novartis Institutes for BioMedical Research
ORCID: 0000-0002-8577-1714
Observed ORCID: 0000-0002-8577-1714
OpenAlex ID: A5083171669
Effects of ginseng components on c-DNA-expressed cytochrome P450 enzyme catalytic activity
1999 · G.L. Henderson, M.R. Harkey, et al. · Life Sciences · 274
Substrate-Dependent Modulation of CYP3A4 Catalytic Activity: Analysis of 27 Test Compounds with Four Fluorometric Substrates
2000 · David M. Stresser, Andrew P. Blanchard, et al. · Drug Metabolism and Disposition · 273
Cytochrome P450 Fluorometric Substrates: Identification of Isoform-Selective Probes for Rat CYP2D2 and Human CYP3A4.
2002 · David M. Stresser, Stephanie D. Turner, et al. · Drug Metabolism and Disposition · 161
In vitro and pharmacophore insights into CYP3A enzymes
2003 · Sean Ekins, David M. Stresser, et al. · Trends in Pharmacological Sciences · 150
A High-Throughput Screen to Identify Inhibitors of Aromatase (CYP19)
2000 · David M. Stresser, Stephanie D. Turner, et al. · Analytical Biochemistry · 138
Highly Selective Inhibition of Human Cyp3a in Vitro by Azamulin and Evidence That Inhibition Is Irreversible
2004 · David M. Stresser, Marc I. Broudy, et al. · Drug Metabolism and Disposition · 129
In Vitro Drug Metabolism Using Liver Microsomes
2016 · Kathleen M. Knights, David M. Stresser, et al. · Current Protocols in Pharmacology · 115
Monospecific Antipeptide Antibody to Cytochrome P-450 2B6
1999 · David M. Stresser, David Kupfer · Drug Metabolism and Disposition · 111
Fluorometric screening for metabolism-based drug–drug interactions
2000 · Charles L. Crespi, David M. Stresser · Journal of Pharmacological and Toxicological Methods · 101
Indole-3-carbinol and beta-naphthoflavone induction of aflatoxin B1 metabolism and cytochromes P-450 associated with bioactivation and detoxication of aflatoxin B1 in the rat.
1994 · D M Stresser, G S Bailey, et al. · Drug Metabolism and Disposition · 96
Fluorometric High‐Throughput Screening for Inhibitors of Cytochrome P450
2000 · VAUGHN P. MILLER, DAVID M. STRESSER, et al. · Annals of the New York Academy of Sciences · 93
Towards in vitro models for reducing or replacing the use of animals in drug testing
2023 · David M. Stresser, Anna K. Kopec, et al. · Nature Biomedical Engineering · 92
Evaluation of Multiple in Vitro Systems for Assessment of CYP3A4 Induction in Drug Discovery: Human Hepatocytes, Pregnane X Receptor Reporter Gene, and Fa2N-4 and HepaRG Cells
2009 · Dermot F. McGinnity, George Zhang, et al. · Drug Metabolism and Disposition · 90
Validation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50shift approach facilitateskinactassay design
2009 · E. S. Perloff, A. K. Mason, et al. · Xenobiotica · 88
Mechanisms of tumor modulation by indole-3-carbinol. Disposition and excretion in male Fischer 344 rats.
1995 · D M Stresser, D E Williams, et al. · Drug Metabolism and Disposition · 87
Indole-3-carbinol induces a rat liver glutathione transferase subunit (Yc2) with high activity toward aflatoxin B1 exo-epoxide. Association with reduced levels of hepatic aflatoxin-DNA adducts in vivo.
1994 · D M Stresser, D E Williams, et al. · Drug Metabolism and Disposition · 76
Tissue-specific expression of flavin-containing monooxygenase (FMO) forms 1 and 2 in the rabbit.
1995 · S E Shehin-Johnson, D E Williams, et al. · Journal of Pharmacology and Experimental Therapeutics · 65
Human cytochrome P450-catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Role of CYP2C19 and CYP1A2 in O-demethylation.
1998 · D M Stresser, D Kupfer · PubMed · 64
The anticarcinogen 3,3′‐diindolylmethane is an inhibitor of cytochrome P‐450
1995 · D. M. Stresser, G. S. Bailey, et al. · Journal of Biochemical and Molecular Toxicology · 54
Concurrent Flavin-Containing Monooxygenase Down Regulation and Cytochrome P450 Induction by Dietary Indoles in the Rat: Implication for Drug-Drug Interactions
2001 · David E. Williams, Sirinmas Katchamart, et al. · Advances in experimental medicine and biology · 50
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Catalytic Characteristics of CYP3A4: Requirement for a Phenolic Function in ortho Hydroxylation of Estradiol and Mono-O-demethylated Methoxychlor
1997 · David M. Stresser, David Kupfer · Biochemistry · 48
Assessing Pregnancy Risks of Azole Antifungals Using a High Throughput Aromatase Inhibition Assay
2002 · Laura Kragie, Stephanie D. Turner, et al. · Endocrine Research · 45
Exploring concepts ofin vitrotime-dependent CYP inhibition assays
2013 · David M Stresser, Jialin Mao, et al. · Expert Opinion on Drug Metabolism & Toxicology · 42
The use of 3-[2-(N,N-diethyl-N-methylammonium)ethyl]-7-methoxy-4-methylcoumarin (AMMC) as a specific CYP2D6 probe in human liver microsomes.
2001 · N Chauret, B Dobbs, et al. · PubMed · 42
Induction of Hepatic CYPIA by Indole-3-Carbinol in Protection Against Aflatoxin B1 Hepatocarcinogenesis in Rainbow Trout
1995 · N. Takahashi, D.M. Stresser, et al. · Food and Chemical Toxicology · 42
Works count: 87
Citation count: 3,142
H-index: 31
I10-index: 47
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