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Philip Cherian

Observed names: Cherian Philip T, P. T. Cherian, Philip T Cherian, Philip T. Cherian
ORCID: 0000-0002-1070-6483
Observed ORCID: 0000-0002-1070-6483
OpenAlex ID: A5083671773
Bisphosphonates: The role of chemistry in understanding their biological actions and structure-activity relationships, and new directions for their therapeutic use
2021 · Frank H. Ebetino, Shuting Sun, et al. · Bone · 96
Chlamydia trachomatis Relies on Autonomous Phospholipid Synthesis for Membrane Biogenesis
2015 · Jiangwei Yao, Philip T. Cherian, et al. · Journal of Biological Chemistry · 51
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Mechanism of bisphosphonate-related osteonecrosis of the jaw (BRONJ) revealed by targeted removal of legacy bisphosphonate from jawbone using competing inert hydroxymethylene diphosphonate
2022 · Hiroko Okawa, Takeru Kondo, et al. · eLife · 39
Bisphosphonates for delivering drugs to bone
2020 · Shuting Sun, Jianguo Tao, et al. · British Journal of Pharmacology · 38
The membrane as a target for controlling hypervirulent Clostridium difficile infections
2012 · X. Wu, P. T. Cherian, et al. · Journal of Antimicrobial Chemotherapy · 38
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Gastrointestinal localization of metronidazole by a lactobacilli-inspired tetramic acid motif improves treatment outcomes in the hamster model ofClostridium difficileinfection
2015 · Philip T. Cherian, Xiaoqian Wu, et al. · Journal of Antimicrobial Chemotherapy · 33
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Chemical Modulation of the Biological Activity of Reutericyclin: a Membrane-Active Antibiotic from Lactobacillusreuteri
2014 · Philip T. Cherian, Xiaoqian Wu, et al. · Scientific Reports · 33
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Evidence of bisphosphonate-conjugated sitafloxacin eradication of established methicillin-resistant S. aureus infection with osseointegration in murine models of implant-associated osteomyelitis
2023 · Youliang Ren, Jason Weeks, et al. · Bone Research · 30
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Development of Bisphosphonate-Conjugated Antibiotics to Overcome Pharmacodynamic Limitations of Local Therapy: Initial Results with Carbamate Linked Sitafloxacin and Tedizolid
2021 · Emmanuela Adjei-Sowah, Yue Peng, et al. · Antibiotics · 23
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SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A
2016 · Chelsi D. Cassilly, Marcus M. Maddox, et al. · PLoS ONE · 23
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Efficacy of Bisphosphonate-Conjugated Sitafloxacin in a Murine Model of S. aureus Osteomyelitis: Evidence of “Target & Release” Kinetics and Killing of Bacteria Within Canaliculi
2022 · Youliang Ren, Thomas Xue, et al. · Frontiers in Cellular and Infection Microbiology · 21
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Bisphosphonates in dentistry: Historical perspectives, adverse effects, and novel applications
2021 · Parish P. Sedghizadeh, Shuting Sun, et al. · Bone · 20
Acyl-sulfamates target the essential glycerol-phosphate acyltransferase (PlsY) in Gram-positive bacteria
2012 · Philip T. Cherian, Jiangwei Yao, et al. · Bioorganic & Medicinal Chemistry · 19
Design, synthesis and microbiological evaluation of ampicillin–tetramic acid hybrid antibiotics
2016 · Philip T Cherian, Aditi Deshpande, et al. · The Journal of Antibiotics · 18
New β-lactam – Tetramic acid hybrids show promising antibacterial activities
2018 · Philip T. Cherian, Martin N. Cheramie, et al. · Bioorganic & Medicinal Chemistry Letters · 16
Real-Time Impedance-Based Monitoring of the Growth and Inhibition of Osteomyelitis Biofilm Pathogen Staphylococcus aureus Treated with Novel Bisphosphonate-Fluoroquinolone Antimicrobial Conjugates
2023 · Parish P. Sedghizadeh, Philip Cherian, et al. · International Journal of Molecular Sciences · 11
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Exploring the PI3Kα and γ binding sites with 2,6-disubstituted isonicotinic derivatives
2009 · Philip T. Cherian, Leonid N. Koikov, et al. · Bioorganic & Medicinal Chemistry Letters · 10
Chemical genetic analysis of enoxolone inhibition of Clostridioides difficile toxin production reveals adenine deaminase and ATP synthase as antivirulence targets
2024 · Ravi K.R. Marreddy, Gregory A. Phelps, et al. · Journal of Biological Chemistry · 9
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Fluorescent risedronate analogue 800CW-pRIS improves tooth extraction-associated abnormal wound healing in zoledronate-treated mice
2022 · Hiroko Okawa, Takeru Kondo, et al. · Communications Medicine · 8
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Real-time impedance-based monitoring of the growth and inhibition of osteomyelitis pathogen Staphylococcus aureus biofilms treated with novel bisphosphonate-fluoroquinolone antimicrobial conjugates
2020 · Parish Sedghizadeh, Esmat Sodagar, et al. · Bone Reports · 1
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Author response: Mechanism of bisphosphonate-related osteonecrosis of the jaw (BRONJ) revealed by targeted removal of legacy bisphosphonate from jawbone using competing inert hydroxymethylene diphosphonate
2022 · Hiroko Okawa, Takeru Kondo, et al. · eLife
The licorice metabolite enoxolone attenuates Clostridioides difficile pathophysiology by corrupting its metabolic and toxin production networks
2022 · Ravi K. R. Marreddy, Jonathan Picker, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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アンピシリン‐テトラミン酸ハイブリッド抗生物質の設計,合成,および微生物学的評価
2017 · Cherian Philip T, Deshpande Aditi, et al.
Exploring the PI3Kα and γ binding sites by homology modeling and inhibitors utilizing a 2,6-disubstituted isonicotinic scaffold
2009 · Philip Cherian · OhioLink ETD Center (Ohio Library and Information Network)
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Works count: 24
Citation count: 537
H-index: 15
I10-index: 17
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