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Alexander J. Pfeil

Observed names: A.J. Pfeil, Alexander James Pfeil, Pfeil, Alexander J.
ORCID: 0000-0002-5159-019X
Observed ORCID: 0000-0002-5159-019X
OpenAlex ID: A5083930279
Dietary Energy Modulation and Autophagy: Exploiting Metabolic Vulnerabilities to Starve Cancer
2020 · Alyssa J. Cozzo, Michael F. Coleman, et al. · Frontiers in Cell and Developmental Biology · 54
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Cell Intrinsic and Systemic Metabolism in Tumor Immunity and Immunotherapy
2020 · Michael F. Coleman, Alyssa J. Cozzo, et al. · Cancers · 36
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Calorie restriction outperforms bariatric surgery in a murine model of obesity and triple-negative breast cancer
2023 · Kristina K. Camp, Michael F. Coleman, et al. · JCI Insight · 17
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Hypoxia-mediated repression of pyruvate carboxylase drives immunosuppression
2024 · Michael F. Coleman, Eylem Kulkoyluoglu Cotul, et al. · Breast Cancer Research · 12
Metabolic Response of Triple-Negative Breast Cancer to Folate Restriction
2021 · Michael F. Coleman, Ciara H. O’Flanagan, et al. · Nutrients · 12
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β-Hydroxy-β-Methylbutyrate Supplementation Promotes Antitumor Immunity in an Obesity Responsive Mouse Model of Pancreatic Ductal Adenocarcinoma
2021 · Michael F. Coleman, Kristyn A. Liu, et al. · Cancers · 8
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Preclinical evaluation of targeted therapies for central nervous system metastases
2024 · Alexander J. Pfeil, Joshua D. Hale, et al. · Disease Models & Mechanisms · 7
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RRAS and RRAS2 Mutations Are Recurrent Oncogenic Drivers in Lung Cancer and Are Sensitive to the Pan-RAS Inhibitor RMC-6236
2026 · Alexander J. Pfeil, Tom Zhang, et al. · Clinical Cancer Research · 3
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Supplementary Data2 from RRAS and RRAS2 Mutations Are Recurrent Oncogenic Drivers in Lung Cancer and Are Sensitive to the Pan-RAS Inhibitor RMC-6236
2026 · Alexander J. Pfeil, Tom Zhang, et al.
Supplementary Data3 from RRAS and RRAS2 Mutations Are Recurrent Oncogenic Drivers in Lung Cancer and Are Sensitive to the Pan-RAS Inhibitor RMC-6236
2026 · Alexander J. Pfeil, Tom Zhang, et al.
Data from RRAS and RRAS2 Mutations Are Recurrent Oncogenic Drivers in Lung Cancer and Are Sensitive to the Pan-RAS Inhibitor RMC-6236
2026 · Alexander J. Pfeil, Tom Zhang, et al.
Supplementary Data6 from RRAS and RRAS2 Mutations Are Recurrent Oncogenic Drivers in Lung Cancer and Are Sensitive to the Pan-RAS Inhibitor RMC-6236
2026 · Alexander J. Pfeil, Tom Zhang, et al.
Supplementary Data1 from RRAS and RRAS2 Mutations Are Recurrent Oncogenic Drivers in Lung Cancer and Are Sensitive to the Pan-RAS Inhibitor RMC-6236
2026 · Alexander J. Pfeil, Tom Zhang, et al.
Supplementary Data5 from RRAS and RRAS2 Mutations Are Recurrent Oncogenic Drivers in Lung Cancer and Are Sensitive to the Pan-RAS Inhibitor RMC-6236
2026 · Alexander J. Pfeil, Tom Zhang, et al.
Supplementary Data4 from RRAS and RRAS2 Mutations Are Recurrent Oncogenic Drivers in Lung Cancer and Are Sensitive to the Pan-RAS Inhibitor RMC-6236
2026 · Alexander J. Pfeil, Tom Zhang, et al.
Abstract A051: Recurrent RRAS and RRAS2 mutations in lung cancer define actionable oncogenic drivers with therapeutic susceptibility to pan-RAS inhibition
2026 · Alexander J. Pfeil, Tom Zhang, et al. · Cancer Research
Molecular landscape and therapeutic vulnerability of RRAS- and RRAS2-mutant solid tumors.
2025 · Alexander James Pfeil, Ryan Cheng, et al. · Journal of Clinical Oncology
Hypoxia-mediated repression of pyruvate carboxylase drives immunosuppression
2024 · Safdar, Muhammad H., Teegarden, Dorothy, et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill)
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P3.03I.10 RRAS and RRAS2 Mutations Are Oncogenic Drivers in Lung Cancer and are Sensitive to the Pan-RAS Inhibitor RMC-6236
2024 · A.J. Pfeil, T. Zhang, et al. · Journal of Thoracic Oncology
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Abstract 1790: Pyruvate carboxylase regulates tumor progression through central carbon metabolism and immunosuppression
2024 · Michael F. Coleman, Eylem Kulkoyluoglu Cotul, et al. · Cancer Research
Abstract 656: Suppression of pyruvate carboxylase drives tumor microenvironment immunosuppression
2023 · Michael F. Coleman, Eylem Kulkoyluoglu Cotul, et al. · Cancer Research
Abstract 1267: Suppression of pyruvate carboxylase drives PDL1 expression in mouse models of TNBC
2023 · Numair Attaar, Alexander J. Pfeil, et al. · Cancer Research
Abstract 2376: Pyruvate carboxylase regulates mammary tumor microenvironment composition via central carbon metabolism
2022 · Alexander J. Pfeil, Michael F. Coleman, et al. · Cancer Research
Abstract 1995: β-Hydroxy-β-methylbutyrate promotes immunotherapy response and pro-inflammatory macrophage polarization in a mouse model of pancreatic cancer
2022 · Michael F. Coleman, Kristyn A. Liu, et al. · Cancer Research
Hypoxia-mediated suppression of pyruvate carboxylase drives tumor microenvironment immunosuppression
2022 · Michael F. Coleman, Eylem Kulkoyluoglu Cotul, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Works count: 26
Citation count: 149
H-index: 7
I10-index: 5
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