Author

Sambuddha Basu

Institutions: F. Hoffmann-La Roche AG, Spark Therapeutics (United States)

Observed institutions: University of Central Florida, F. Hoffmann-La Roche AG, National Institutes of Health, Spark Therapeutics (United States), National Institute on Aging

ORCID: 0000-0002-1281-1543

Observed ORCID: 0000-0002-1281-1543

OpenAlex ID: A5083960100

Targeted attenuation of elevated histone marks at SNCA alleviates α‐synuclein in Parkinson's disease

2021 · Subhrangshu Guhathakurta, Jinil Kim, et al. · EMBO Molecular Medicine · 95

Mitophagy and DNA damage signaling in human aging

2020 · Mansi Babbar, Sambuddha Basu, et al. · Mechanisms of Ageing and Development · 77

Biological sex and DNA repair deficiency drive Alzheimer’s disease via systemic metabolic remodeling and brain mitochondrial dysfunction

2020 · Tyler G. Demarest, Vijay R. Varma, et al. · Acta Neuropathologica · 72

Hypomethylation of intron1 of α-synuclein gene does not correlate with Parkinson’s disease

2017 · Subhrangshu Guhathakurta, Baggio A. Evangelista, et al. · Molecular Brain · 50

Transcriptional mutagenesis by 8-oxodG in α-synuclein aggregation and the pathogenesis of Parkinson’s disease

2015 · Sambuddha Basu, Goun Je, et al. · Experimental & Molecular Medicine · 39

A novel tool for monitoring endogenous alpha-synuclein transcription by NanoLuciferase tag insertion at the 3′end using CRISPR-Cas9 genome editing technique

2017 · Sambuddha Basu, Levi Adams, et al. · Scientific Reports · 22

Endogenous Alpha-Synuclein Protein Analysis from Human Brain Tissues Using Single-Molecule Pull-Down Assay

2017 · Goun Je, Benjamin Croop, et al. · Analytical Chemistry · 21

Transcriptional mutagenesis of α-synuclein caused by DNA oxidation in Parkinson’s disease pathogenesis

2023 · Sambuddha Basu, Minkyung Song, et al. · Acta Neuropathologica · 19

Regulation of Αlpha-Synuclein Gene (SNCA) by Epigenetic Modifier TET1 in Parkinson Disease

2022 · Subhrangshu Guhathakurta, Min Kyung Song, et al. · International Neurourology Journal · 10

Restoring Parkin function: an AAV gene therapy approach for early-onset Parkinson’s disease

2026 · Sambuddha Basu, Tyler G. Demarest, et al. · Frontiers in Molecular Neuroscience

Implication of Alpha-synuclein Transcriptional Regulation and Mutagenesis in the Pathogenesis of Sporadic Parkinson's Disease

2017 · Sambuddha Basu · Journal of International Crisis and Risk Communication Research

Works count: 11

Citation count: 405

H-index: 9

I10-index: 9