Author

Pascale M.N. Tiger

Observed names: P Tiger, Pascale M. N. Tiger, Pascale Tiger, Tiger Pascale

Institution: BioMarin (United States)

Observed institutions: University of Sheffield, BioMarin (United States)

OpenAlex ID: A5083993771

Delivery of an enzyme-IGFII fusion protein to the mouse brain is therapeutic for mucopolysaccharidosis type IIIB

2014 · Shih-hsin Kan, Mika Aoyagi-Scharber, et al. · Proceedings of the National Academy of Sciences · 111

Intrathecal tripeptidyl-peptidase 1 reduces lysosomal storage in a canine model of late infantile neuronal ceroid lipofuscinosis

2011 · Brian R. Vuillemenot, Martin L. Katz, et al. · Molecular Genetics and Metabolism · 78

Quantitative Measurements of Edge‐to‐Face Aromatic Interactions by Using Chemical Double‐Mutant Cycles

2001 · Fiona J. Carver, Christopher A. Hunter, et al. · Chemistry - A European Journal · 51

Clearance of Heparan Sulfate and Attenuation of CNS Pathology by Intracerebroventricular BMN 250 in Sanfilippo Type B Mice

2017 · Mika Aoyagi-Scharber, Danielle Crippen-Harmon, et al. · Molecular Therapy — Methods & Clinical Development · 36

Chemical Triple-Mutant Boxes for Quantifying Cooperativity in Intermolecular Interactions

2002 · Christopher A. Hunter, Philip S. Jones, et al. · Chemistry - A European Journal · 22

Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B

2020 · Anita Grover, Danielle Crippen-Harmon, et al. · Drug Delivery and Translational Research · 15

New building blocks for the assembly of sequence selective molecular zippers

2003 · Chistopher A. Hunter, Philip S. Jones, et al. · Chemical Communications · 15

Engineering of a recombinant NAGLU fusion protein with insulin-like growth factor 2 leads to improved cellular uptake via a glycosylation-independent lysosomal targeting pathway

2014 · Mika Aoyagi-Scharber, Terri Christianson, et al. · Molecular Genetics and Metabolism · 4

Mannose 6-Phosphate Conjugation Is Not Sufficient to Allow Induction of Immune Tolerance to Phenylalanine Ammonia-Lyase in Dogs

2012 · Moin Vera, Thomas Lester, et al. · JIMD Reports · 3

Intracerebroventricular dosing of N-sulfoglucosamine sulfohydrolase in mucopolysaccharidosis IIIA mice reduces markers of brain lysosomal dysfunction

2022 · Jenna Magat, Samantha Jones, et al. · Journal of Biological Chemistry · 2

Histologic characterization of the progression of central nervous system pathology in the mucopolysaccharidosis IIIB (MPS IIIB, Sanfilippo syndrome type B) mouse model and bio-distribution and efficacy of the intracerebroventricular enzyme replacement therapy, BMN 250

2016 · Anil Bagri, Danielle Harmon, et al. · Molecular Genetics and Metabolism · 1

Time- and dose-dependent normalization of pathological lysosomal storage and biochemistry in the mucopolysaccharidosis ΙΙΙΒ (MPS ΙΙΙΒ, Sanfilippo syndrome type Β) mouse model by intracerebroventricular enzyme replacement therapy with ΒΜΝ 250, a ΝAGLU-ΙGF2 fusion pro

2016 · Mika Aoyagi-Scharber, Jon Vincelette, et al. · Molecular Genetics and Metabolism

Glycosylation independent lysosomal targeting of alpha-n-acetylglucosaminidase confers highly efficient enzyme uptake into critical cellular targets of disease pathogenesis in mucopolysaccharidosis type IIIB

2016 · Gouri Yogalingam, Heather Prill, et al. · Molecular Genetics and Metabolism

Bmn250 (maglu‐igf2)の脳室内投与はmps Iiibマウスのリソソーム病理を正常化する

2016 · Aoyagi‐Scharber Mika, Crippen‐Harmon Danielle, et al. · 日本先天代謝異常学会雑誌

PP4.5 – 1813 Nonclinical development of rhTPP1 enzyme replacement therapy for NCL2

2013 · BR Vuillemenot, D Kennedy, et al. · European Journal of Paediatric Neurology

Quantitative Measurements of Edge-to-Face Aromatic Interactions by Using Chemical Double-Mutant Cycles

2001 · Fiona J. Carver, Christopher A. Hunter, et al. · Chemistry - A European Journal

Works count: 16

Citation count: 338

H-index: 7

I10-index: 7