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Laura Dearden
Observed names:
Dearden, LA,
Dearden, Laura,
L. Dearden,
LAURA DEARDEN
Institutions:
University of Cambridge,
Wellcome/MRC Institute of Metabolic Science
Observed institutions:
University of Liverpool,
University of Cambridge,
University of Bristol,
Wellcome/MRC Institute of Metabolic Science,
Addenbrooke's Hospital,
MRC Metabolic Diseases Unit,
Wellcome Trust
show all 7
ORCID:
0000-0002-0804-074X
Observed ORCID:
0000-0002-0804-074X
OpenAlex ID:
A5084067366
Sex and gender differences in developmental programming of metabolism
2018
·
Laura Dearden
, Sebastien G. Bouret
, et al.
·
Molecular Metabolism
·
347
PDF
SENP3‐mediated deSUMOylation of dynamin‐related protein 1 promotes cell death following ischaemia
2013
·
Chun Guo
, Keri L Hildick
, et al.
·
The EMBO Journal
·
226
Early life origins of metabolic disease: Developmental programming of hypothalamic pathways controlling energy homeostasis
2015
·
Laura Dearden
, Susan E. Ozanne
·
Frontiers in Neuroendocrinology
·
131
Decreased ovarian reserve, dysregulation of mitochondrial biogenesis, and increased lipid peroxidation in female mouse offspring exposed to an obesogenic maternal diet
2015
·
Catherine E. Aiken
, Jane L. Tarry‐Adkins
, et al.
·
The FASEB Journal
·
92
PDF
Enhanced SUMOylation and SENP-1 Protein Levels following Oxygen and Glucose Deprivation in Neurones
2011
·
Helena Cimarosti
, Emi Ashikaga
, et al.
·
Journal of Cerebral Blood Flow & Metabolism
·
78
PDF
Maternal obesity causes fetal hypothalamic insulin resistance and disrupts development of hypothalamic feeding pathways
2020
·
L. Dearden
, S. Buller
, et al.
·
Molecular Metabolism
·
76
PDF
Maternal exercise intervention in obese pregnancy improves the cardiovascular health of the adult male offspring
2018
·
Jessica H. Beeson
, Heather L. Blackmore
, et al.
·
Molecular Metabolism
·
73
Sexual Dimorphism in Offspring Glucose-Sensitive Hypothalamic Gene Expression and Physiological Responses to Maternal High-Fat Diet Feeding
2014
·
Laura Dearden
, Nina Balthasar
·
Endocrinology
·
70
PDF
Programming of cardiometabolic health: the role of maternal and fetal hyperinsulinaemia
2022
·
Antonia Hufnagel
, Laura Dearden
, et al.
·
Journal of Endocrinology
·
66
PDF
Programming of central and peripheral insulin resistance by low birthweight and postnatal catch-up growth in male mice
2018
·
Lindsey M. Berends
, Laura Dearden
, et al.
·
Diabetologia
·
65
PDF
Large-scale exome sequence analysis identifies sex- and age-specific determinants of obesity
2023
·
Lena R. Kaisinger
, Katherine A. Kentistou
, et al.
·
Cell Genomics
·
49
The deubiquitylase USP15 stabilizes newly synthesized REST and rescues its expression at mitotic exit
2013
·
Monica Faronato
, Vruti Patel
, et al.
·
Cell Cycle
·
45
Sex-specific effects of maternal metformin intervention during glucose-intolerant obese pregnancy on body composition and metabolic health in aged mouse offspring
2022
·
Josca M. Schoonejans
, Heather L. Blackmore
, et al.
·
Diabetologia
·
28
PDF
Early life impacts of maternal obesity: a window of opportunity to improve the health of two generations
2023
·
Laura Dearden
, Susan E. Ozanne
·
Philosophical Transactions of the Royal Society B Biological Sciences
·
25
PDF
Mechanisms mediating the impact of maternal obesity on offspring hypothalamic development and later function
2022
·
Isadora C. Furigo
, Laura Dearden
·
Frontiers in Endocrinology
·
21
PDF
Nutritional and developmental programming effects of insulin
2021
·
Laura Dearden
, Sebastien G. Bouret
, et al.
·
Journal of Neuroendocrinology
·
18
Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food
2024
·
Laura Dearden
, Isadora C. Furigo
, et al.
·
PLoS Biology
·
15
Programming of cardiac metabolism by miR-15b-5p, a miRNA released in cardiac extracellular vesicles following ischemia-reperfusion injury
2024
·
Lucas C. Pantaleão
, Elena Loche
, et al.
·
Molecular Metabolism
·
13
Incretin receptor agonism during pregnancy: implications for mother and baby
2025
·
Laura Dearden
, Susan E. Ozanne
·
Clinical Science
·
12
PDF
Exploring Telomere Dynamics in Aging Male Rat Tissues: Can Tissue-Specific Differences Contribute to Age-Associated Pathologies?
2021
·
Jane L. Tarry-Adkins
, Catherine E. Aiken
, et al.
·
Gerontology
·
8
PDF
Maternal high fat and high sugar diet impacts on key DNA methylation enzymes in offspring brain in a sex‐specific manner
2025
·
Kahyee Hor
, Laura Dearden
, et al.
·
Journal of Neuroendocrinology
·
7
PDF
Considerations for designing and analysing inter-generational studies in rodents
2023
·
Laura Dearden
, Susan E. Ozanne
·
Nature Metabolism
·
6
PDF
The road between early growth and obesity: new twists and turns
2014
·
Laura Dearden
, Susan E Ozanne
·
American Journal of Clinical Nutrition
·
4
PDF
The long-term impact of obesity in pregnancy on offspring hypothalamic feeding pathways
2025
·
Pit Shan Chong
, Laura Dearden
·
Royal Society Open Science
·
3
PDF
Healthy baby after intrauterine transfer of monosomic embryos
2016
·
P. Rubino
, L. Dearden
, et al.
·
Fertility and Sterility
·
3
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Works count:
47
Citation count:
1,484
H-index:
16
I10-index:
19
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