Author

Nandini N. Kishore

Observed names: N. Kishore, Nandini Kishore

Observed institution: Pfizer (United States)

OpenAlex ID: A5084129668

Modulation of Innate and Adaptive Immune Responses by Tofacitinib (CP-690,550)

2011 · Kamran Ghoreschi, Michael I Jesson, et al. · The Journal of Immunology · 642

Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis

2010 · Debra M Meyer, Michael I Jesson, et al. · Journal of Inflammation · 462

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A Selective IKK-2 Inhibitor Blocks NF-κB-dependent Gene Expression in Interleukin-1β-stimulated Synovial Fibroblasts

2003 · Nandini Kishore, Cindy Sommers, et al. · Journal of Biological Chemistry · 271

Therapeutic targeting of Janus kinases

2008 · Marko Pesu, Arian Laurence, et al. · Immunological Reviews · 230

JAK inhibition with tofacitinib suppresses arthritic joint structural damage through decreased RANKL production

2012 · Timothy P. LaBranche, Michael I. Jesson, et al. · Arthritis & Rheumatism · 140

IKK-i and TBK-1 are Enzymatically Distinct from the Homologous Enzyme IKK-2

2002 · Nandini Kishore, Q. Khai Huynh, et al. · Journal of Biological Chemistry · 138

Preclinical to Clinical Translation of Tofacitinib, a Janus Kinase Inhibitor, in Rheumatoid Arthritis

2013 · Martin E. Dowty, Michael I. Jesson, et al. · Journal of Pharmacology and Experimental Therapeutics · 117

Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease

2003 · Srinivasan R Nagarajan, Gary A De Crescenzo, et al. · Bioorganic & Medicinal Chemistry · 95

A Novel, Highly Selective, Tight Binding IκB Kinase-2 (IKK-2) Inhibitor: A Tool to Correlate IKK-2 Activity to the Fate and Functions of the Components of the Nuclear Factor-κB Pathway in Arthritis-Relevant Cells and Animal Models

2009 · Gabriel Mbalaviele, Cynthia D. Sommers, et al. · Journal of Pharmacology and Experimental Therapeutics · 62

Protein Kinase Cζ Mediates Cigarette Smoke/Aldehyde- and Lipopolysaccharide-induced Lung Inflammation and Histone Modifications

2009 · Hongwei Yao, Jae-woong Hwang, et al. · Journal of Biological Chemistry · 60

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Anti-inflammatory effect of a selective IκB kinase-beta inhibitor in rat lung in response to LPS and cigarette smoke

2010 · Saravanan Rajendrasozhan, Jae-Woong Hwang, et al. · Pulmonary Pharmacology & Therapeutics · 47

Novel Insights into the Cellular Mechanisms of the Anti-inflammatory Effects of NF-κB Essential Modulator Binding Domain Peptides

2010 · Eric T. Baima, Julia A. Guzova, et al. · Journal of Biological Chemistry · 42

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Novel Tight-Binding Inhibitory Factor-κB Kinase (IKK-2) Inhibitors Demonstrate Target-Specific Anti-Inflammatory Activities in Cellular Assays and following Oral and Local Delivery in an in Vivo Model of Airway Inflammation

2009 · Cynthia D. Sommers, Janice M. Thompson, et al. · Journal of Pharmacology and Experimental Therapeutics · 33

Inhibition of IKK-2 by 2-[(aminocarbonyl)amino]-5-acetylenyl-3-thiophenecarboxamides

2005 · Dominique Bonafoux, Sheri Bonar, et al. · Bioorganic & Medicinal Chemistry Letters · 30

Kinetic Mechanisms of IκB-related Kinases (IKK) Inducible IKK and TBK-1 Differ from IKK-1/IKK-2 Heterodimer

2002 · Q. Khai Huynh, Nandini Kishore, et al. · Journal of Biological Chemistry · 26

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Discovery of a novel series of selective MMP inhibitors: Identification of the γ-sulfone-thiols

1999 · John N. Freskos, Brent V. Mischke, et al. · Bioorganic & Medicinal Chemistry Letters · 24

Aminopyridinecarboxamide-based inhaled IKK-2 inhibitors for asthma and COPD: Structure–activity relationship

2010 · Jin Xie, Gennadiy I. Poda, et al. · Bioorganic & Medicinal Chemistry · 16

(Hydroxyethyl) sulfonamide HIV-1 Protease inhibitors: Identification of the 2-methylbenzoyl moiety at P-2

1996 · John N. Freskos, Deborah E. Bertenshaw, et al. · Bioorganic & Medicinal Chemistry Letters · 10

Combined use of pharmacokinetic modeling and a steady-state delivery approach allows early assessment of IκB kinase-2 (IKK-2) target safety and efficacy

2009 · Po-Chang Chiang, Nandini N. Kishore, et al. · Journal of Pharmaceutical Sciences · 6

Expression, purification and functional characterization of IκB kinase-2 (IKK-2) mutants

2010 · Sumathy Mathialagan, Gennadiy I. Poda, et al. · Protein Expression and Purification · 4

AB0160 Effects of TOFACITINIB (CP-690,550) on lipid biomarkers in rat adjuvant-induced arthritis (AIA) model and in patients with active rheumatoid arthritis

2012 · I. McInnes, I. Kaplan, et al. · Annals of the Rheumatic Diseases · 2

Works count: 21

Citation count: 2,457

H-index: 16

I10-index: 18