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Fakher Chabchoub

Observed names: CHABCHOUB, Fakher, Chabchoub, F., Chabchoub, Fakher, F. Chabchoub, Fakher CHABCHOUB, Fakher Chabchoub,
ORCID: 0000-0003-4375-0277
Observed ORCID: 0000-0003-4375-0277
OpenAlex ID: A5084469840
Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines as potential drugs for the treatment of Alzheimer's disease
2012 · Emna Maalej, Fakher Chabchoub, et al. · European Journal of Medicinal Chemistry · 69
Synthesis and antigenotoxic activity of some naphtho[2,1-b]pyrano[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives
2006 · Fakher Chabchoub, Mehdi Messaâd, et al. · European Journal of Medicinal Chemistry · 63
New Dual Small Molecules for Alzheimer’s Disease Therapy Combining Histamine H 3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition
2019 · Rim Malek, Raquel L. Arribas, et al. · Journal of Medicinal Chemistry · 44
Tetrahydropyranodiquinolin-8-amines as new, non hepatotoxic, antioxidant, and acetylcholinesterase inhibitors for Alzheimer's disease therapy
2016 · Youssef Dgachi, Olga Sokolov, et al. · European Journal of Medicinal Chemistry · 42
Multi-target 1,4-dihydropyridines showing calcium channel blockade and antioxidant capacity for Alzheimer’s disease therapy
2019 · Rim Malek, Maciej Maj, et al. · Bioorganic Chemistry · 38
Synthesis, biological assessment and molecular modeling of 14-aryl-10,11,12,14-tetrahydro-9H-benzo[5,6]chromeno[2,3-b]quinolin-13-amines
2011 · Emna Maalej, Fakher Chabchoub, et al. · Bioorganic & Medicinal Chemistry Letters · 36
Tacrines as Therapeutic Agents for Alzheimer's Disease. V. Recent Developments
2020 · Óscar M. Bautista‐Aguilera, Lhassane Ismaili, et al. · The Chemical Record · 34
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Synthesis, antimicrobial and antioxidant activities of imidazotriazoles and new multicomponent reaction toward 5-amino-1-phenyl[1,2,4]triazole derivatives
2015 · Monia Aouali, Dhekra Mhalla, et al. · Medicinal Chemistry Research · 34
Nontoxic and Neuroprotective β-Naphthotacrines for Alzheimer’s Disease
2013 · Mario Esquivias-Pérez, Emna Maalej, et al. · Chemical Research in Toxicology · 34
Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer’s Disease
2016 · Youssef Dgachi, Oscar Bautista-Aguilera, et al. · Molecules · 33
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Synthesis of aminocyanopyrazoles via a multi-component reaction and anti-carbonic anhydrase inhibitory activity of their sulfamide derivatives against cytosolic and transmembrane isoforms
2012 · Fatma Allouche, Fakher Chabchoub, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 28
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Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Aβ1−42 Aggregation Inhibitors for Alzheimer's Disease Therapy
2016 · Youssef Dgachi, Lhassane Ismaili, et al. · ChemMedChem · 27
Synthesis and pharmacological evaluation of pyrazolopyrimidopyrimidine derivatives: anti-inflammatory agents with gastroprotective effect in rats
2013 · Amine Karoui, Fatma Allouche, et al. · Medicinal Chemistry Research · 24
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Three Component One-Pot Synthesis and Antiproliferative Activity of New [1,2,4]Triazolo[4,3-a]pyrimidines
2023 · Manel Ben Hassen, Dhouha Msalbi, et al. · Molecules · 23
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Purification and structure elucidation of two biologically active molecules from a new isolated Streptomyces sp. US 24 strain
2004 · R. Mehdi-Ben Ameur, L. Mellouli, et al. · Chemistry of Natural Compounds · 22
Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer’s disease therapy
2018 · Youssef Dgachi, Hélène Martin, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 21
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Synthesis and biological assessment of new pyrimidopyrimidines as inhibitors of breast cancer resistance protein (ABCG2)
2021 · Imen Dakhlaoui, Sahel Vahdati, et al. · Bioorganic Chemistry · 18
New 3-substituted-2,1-benzisoxazoles: Synthesis and antimicrobial activities
2013 · Aida Chaker, Ennaji Najahi, et al. · Arabian Journal of Chemistry · 17
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Sc(OTf)3 promoted multicomponent synthesis of fluorescent imidazo[1,2-c]pyrazolo[3,4-d]pyrimidine
2013 · Asma Agrebi, Fatma Allouche, et al. · Tetrahedron Letters · 17
ACTION OF PRIMARY AMINES AND HYDROXYLAMINE ON ETHOXYMETHYLENEAMINONAPHTOPYRANES: SYNTHESIS OF NEW NAPHTOPYRANO [2,3-d] PYRIMIDINES DERIVATIVES
2005 · Mehadi Messaád,, Fakher Chabchoub,, et al. · Heterocyclic Communications · 17
Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer’s Disease Therapy
2020 · Lazhar Zribi, Irene Pachòn-Angona, et al. · Molecules · 16
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Synthesis, Antibacterial, and Antifungal Activities of Imidazo[2,1-c][1,2,4]triazoles and 1,2,4-Triazolo[4,3-a]pyrimidinones
2014 · Monia Aouali, Fatma Allouche, et al. · Synthetic Communications · 14
Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation
2022 · Rim Malek, Alexey Simakov, et al. · Molecules · 13
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Isoxazolotacrines as Non-Toxic and Selective Butyrylcholinesterase Inhibitors for Alzheimer'S Disease
2014 · Oussama Cherif, Fatma Allouche, et al. · Future Medicinal Chemistry · 13
Action Des Phosphodihydrazides Sur Les Sels D'imidates Et Les N-acylimidates: Nouvelle Methode D'obtention Des Tetrazaphosphorines
2004 · Awatef Rekik, Fakher Chabchoub, et al. · Phosphorus, sulfur, and silicon and the related elements · 13
Works count: 94
Citation count: 926
H-index: 17
I10-index: 34
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