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Ryunosuke Yoshino
Observed names:
Ryunosuke YOSHINO,
Yoshino, Ryunosuke,
吉野 龍ノ介
Institutions:
University of Tsukuba,
Transborder Medical Research Center
Observed institutions:
Tokyo Institute of Technology,
University of Tsukuba,
Transborder Medical Research Center,
Center for Computational Sciences, University of Tsukuba,
The University of Tokyo
ORCID:
0000-0002-5123-1349
Observed ORCID:
0000-0002-5123-1349
OpenAlex ID:
A5085299607
Identification of key interactions between SARS-CoV-2 main protease and inhibitor drug candidates
2020
·
Ryunosuke Yoshino
, Nobuaki Yasuo
, et al.
·
Scientific Reports
·
113
PDF
Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti
2022
·
Kazue Inaba
, Kana Ebihara
, et al.
·
BMC Biology
·
51
PDF
Pharmacophore Modeling for Anti-Chagas Drug Design Using the Fragment Molecular Orbital Method
2015
·
Ryunosuke Yoshino
, Nobuaki Yasuo
, et al.
·
PLoS ONE
·
45
PDF
Exploring the selectivity of inhibitor complexes with Bcl-2 and Bcl-XL: A molecular dynamics simulation approach
2017
·
Naoki Wakui
, Ryunosuke Yoshino
, et al.
·
Journal of Molecular Graphics and Modelling
·
44
Identification of potential inhibitors based on compound proposal contest: Tyrosine-protein kinase Yes as a target
2015
·
Shuntaro Chiba
, Kazuyoshi Ikeda
, et al.
·
Scientific Reports
·
40
PDF
Molecular Dynamics Simulation reveals the mechanism by which the Influenza Cap-dependent Endonuclease acquires resistance against Baloxavir marboxil
2019
·
Ryunosuke Yoshino
, Nobuaki Yasuo
, et al.
·
Scientific Reports
·
38
PDF
The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis
2021
·
Motohiro Sekiya
, Kenta Kainoh
, et al.
·
Nature Communications
·
33
PDF
An iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes
2017
·
Shuntaro Chiba
, Takashi Ishida
, et al.
·
Scientific Reports
·
29
PDF
A prospective compound screening contest identified broader inhibitors for Sirtuin 1
2019
·
Shuntaro Chiba
, Masahito Ohue
, et al.
·
Scientific Reports
·
28
PDF
An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo
2020
·
Kotaro Koiwai
, Kazue Inaba
, et al.
·
Journal of Biological Chemistry
·
26
PDF
In silico, in vitro, X-ray crystallography, and integrated strategies for discovering spermidine synthase inhibitors for Chagas disease
2017
·
Ryunosuke Yoshino
, Nobuaki Yasuo
, et al.
·
Scientific Reports
·
26
PDF
Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity
2023
·
Kenji Saito
, Motohiro Sekiya
, et al.
·
Journal of Biological Chemistry
·
21
PDF
Construction of PROTAC-Mediated Ternary Complex Structure Distribution Profiles Using Extensive Conformational Search
2025
·
Genki Kudo
, Takumi Hirao
, et al.
·
Journal of Chemical Information and Modeling
·
18
PDF
Discovery of a Hidden Trypanosoma cruzi Spermidine Synthase Binding Site and Inhibitors through In Silico, In Vitro , and X-ray Crystallography
2023
·
Ryunosuke Yoshino
, Nobuaki Yasuo
, et al.
·
ACS Omega
·
17
PDF
CrypToth: Cryptic Pocket Detection through Mixed-Solvent Molecular Dynamics Simulations-Based Topological Data Analysis
2025
·
Jun Koseki
, Chie Motono
, et al.
·
Journal of Chemical Information and Modeling
·
13
PDF
Non-steroidal inhibitors of Drosophila melanogaster steroidogenic glutathione S-transferase Noppera-bo
2021
·
Kotaro Koiwai
, Kana Morohashi
, et al.
·
Journal of Pesticide Science
·
12
PDF
AAp-MSMD: Amino Acid Preference Mapping on Protein–Protein Interaction Surfaces Using Mixed-Solvent Molecular Dynamics
2023
·
Genki Kudo
, Keisuke Yanagisawa
, et al.
·
Journal of Chemical Information and Modeling
·
8
PDF
Chemosynthetic ethanolamine plasmalogen stimulates gonadotropin secretion from bovine gonadotrophs by acting as a potential GPR61 agonist
2022
·
Hiroya Kadokawa
, Ryunosuke Yoshino
, et al.
·
Animal Reproduction Science
·
8
Prediction of the binding mechanism of a selective DNA methyltransferase 3A inhibitor by molecular simulation
2024
·
Genki Kudo
, Takumi Hirao
, et al.
·
Scientific Reports
·
7
Pocket to concavity: a tool for the refinement of protein–ligand binding site shape from alpha spheres
2023
·
Genki Kudo
, Takumi Hirao
, et al.
·
Bioinformatics
·
7
PDF
Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis
2022
·
Junya Tabata
, Takashi Nakaoku
, et al.
·
Cancer Research
·
6
PDF
Temperature–pressure shuffling outlier flooding method enhances the conformational sampling of proteins
2019
·
Ryuhei Harada
, Ryunosuke Yoshino
, et al.
·
Journal of Computational Chemistry
·
5
Compound property enhancement by virtual compound synthesis
2018
·
Naoki Arai
, Shunsuke Yoshikawa
, et al.
·
Journal of Bioinformatics and Computational Biology
·
5
A unique peptide-based pharmacophore identifies an inhibitory compound against the A-subunit of Shiga toxin
2022
·
Miho Watanabe-Takahashi
, Miki Senda
, et al.
·
Scientific Reports
·
4
PDF
Site Identification and Next Choice Protocol for Hit-to-Lead Optimization
2024
·
Genki Kudo
, Takumi Hirao
, et al.
·
Journal of Chemical Information and Modeling
·
3
PDF
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Works count:
73
Citation count:
619
H-index:
14
I10-index:
16
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