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Morihiko Hirota

Observed names: M. Hirota, Morihiko HIROTA
Observed institution: Shiseido Group (Japan)
ORCID: 0000-0002-4110-5015
Observed ORCID: 0000-0002-4110-5015
OpenAlex ID: A5085642022
Development of an in vitro skin sensitization test using human cell lines: The human Cell Line Activation Test (h-CLAT)
2005 · T. Ashikaga, Y. Yoshida, et al. · Toxicology in Vitro · 342
Development of an in vitro skin sensitization test using human cell lines; human Cell Line Activation Test (h-CLAT) II. An inter-laboratory study of the h-CLAT
2005 · H. Sakaguchi, T. Ashikaga, et al. · Toxicology in Vitro · 222
Test battery with the human cell line activation test, direct peptide reactivity assay and DEREK based on a 139 chemical data set for predicting skin sensitizing potential and potency of chemicals
2015 · Osamu Takenouchi, Shiho Fukui, et al. · Journal of Applied Toxicology · 120
Prediction of skin sensitization potency of chemicals by human Cell Line Activation Test (h-CLAT) and an attempt at classifying skin sensitization potency
2012 · Yuko Nukada, Takao Ashikaga, et al. · Toxicology in Vitro · 117
QUANTITATIVE MEASUREMENT OF SPLICED XBP1 mRNA AS AN INDICATOR OF ENDOPLASMIC RETICULUM STRESS
2006 · Morihiko HIROTA, Masato KITAGAKI, et al. · The Journal of Toxicological Sciences · 112
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Development of a next generation risk assessment framework for the evaluation of skin sensitisation of cosmetic ingredients
2020 · Nicola Gilmour, Petra S. Kern, et al. · Regulatory Toxicology and Pharmacology · 93
Predictive performance for human skin sensitizing potential of the human cell line activation test (h-CLAT)
2011 · Yuko Nukada, Takao Ashikaga, et al. · Contact Dermatitis · 92
Evaluation of combinations of in vitro sensitization test descriptors for the artificial neural network‐based risk assessment model of skin sensitization
2015 · Morihiko Hirota, Shiho Fukui, et al. · Journal of Applied Toxicology · 61
Evaluation of changes of cell-surface thiols as a new biomarker for in vitro sensitization test
2009 · Mie Suzuki, Morihiko Hirota, et al. · Toxicology in Vitro · 61
Chemical photoallergy: photobiochemical mechanisms, classification, and risk assessments
2016 · Satomi Onoue, Yoshiki Seto, et al. · Journal of Dermatological Science · 55
Skin sensitization risk assessment model using artificial neural network analysis of data from multiple in vitro assays
2014 · Kyoko Tsujita-Inoue, Morihiko Hirota, et al. · Toxicology in Vitro · 55
Development of an artificial neural network model for risk assessment of skin sensitization using human cell line activation test, direct peptide reactivity assay, KeratinoSens™ and in silico structure alert parameter
2017 · Morihiko Hirota, Takao Ashikaga, et al. · Journal of Applied Toxicology · 52
Non-animal photosafety assessment approaches for cosmetics based on the photochemical and photobiochemical properties
2013 · Satomi Onoue, Gen Suzuki, et al. · Toxicology in Vitro · 46
Oxidation of Cell Surface Thiol Groups by Contact Sensitizers Triggers the Maturation of Dendritic Cells
2009 · Saori Kagatani, Yoshinori Sasaki, et al. · Journal of Investigative Dermatology · 36
Artificial neural network analysis of data from multiple in vitro assays for prediction of skin sensitization potency of chemicals
2013 · Morihiko Hirota, Hirokazu Kouzuki, et al. · Toxicology in Vitro · 35
MIP-1β, a novel biomarker for in vitro sensitization test using human monocytic cell line
2005 · Morihiko Hirota, Osamu Moro · Toxicology in Vitro · 35
Development of an in vitro photosensitization assay using human monocyte-derived cells
2009 · Masatoshi Hoya, Morihiko Hirota, et al. · Toxicology in Vitro · 27
Modification of cell-surface thiols elicits activation of human monocytic cell line THP-1: Possible involvement in effect of haptens 2,4-dinitrochlorobenzene and nickel sulfate
2009 · Morihiko Hirota, Mie Suzuki, et al. · The Journal of Toxicological Sciences · 24
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In silico risk assessment for skin sensitization using artificial neural network analysis
2015 · Kyoko Tsujita-Inoue, Tomomi Atobe, et al. · The Journal of Toxicological Sciences · 21
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Mechanism-based integrated assay systems for the prediction of drug-induced liver injury
2020 · Moemi Kawaguchi, Takumi Nukaga, et al. · Toxicology and Applied Pharmacology · 19
Prediction of genotoxic potential of cosmetic ingredients by an in silico battery system consisting of a combination of an expert rule-based system and a statistics-based system
2015 · Maki Aiba née Kaneko, Morihiko Hirota, et al. · The Journal of Toxicological Sciences · 18
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A step-by-step approach for assessing acute oral toxicity without animal testing for additives of quasi-drugs and cosmetic ingredients
2022 · Hajime Kojima, Tokio Nakada, et al. · Current Research in Toxicology · 15
Development of novel in vitro photosafety assays focused on the Keap1–Nrf2–ARE pathway
2015 · Kyoko Tsujita‐Inoue, Morihiko Hirota, et al. · Journal of Applied Toxicology · 15
Non-animal photosafety screening for complex cosmetic ingredients with photochemical and photobiochemical assessment tools
2015 · Hayato Nishida, Morihiko Hirota, et al. · Regulatory Toxicology and Pharmacology · 14
Changes of cell-surface thiols and intracellular signaling in human monocytic cell line THP-1 treated with diphenylcyclopropenone
2010 · Morihiko Hirota, Akira Motoyama, et al. · The Journal of Toxicological Sciences · 14
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Works count: 53
Citation count: 1,781
H-index: 19
I10-index: 29
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