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Charles D. Chen

Observed names: C.D. Chen, Charles Chen, Charles D Chen
ORCID: 0000-0001-6698-1268
Observed ORCID: 0000-0001-6698-1268
OpenAlex ID: A5085814486
Highly accurate blood test for Alzheimer’s disease is similar or superior to clinical cerebrospinal fluid tests
2024 · Nicolas R. Barthélemy, Gemma Salvadó, et al. · Nature Medicine · 439
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CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease
2023 · Kanta Horie, Gemma Salvadó, et al. · Nature Medicine · 246
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Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer’s disease
2023 · Erik C. B. Johnson, Shijia Bian, et al. · Nature Medicine · 170
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Disease staging of Alzheimer’s disease using a CSF-based biomarker model
2024 · Gemma Salvadó, Kanta Horie, et al. · Nature Aging · 113
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Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study
2022 · Anna H Boerwinkle, Brian A Gordon, et al. · The Lancet Neurology · 55
Novelty, Salience, and Surprise Timing Are Signaled by Neurons in the Basal Forebrain
2018 · Kaining Zhang, Charles D. Chen, et al. · Current Biology · 55
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Amyloid‐Related Imaging Abnormalities in the DIAN‐TU ‐001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease
2022 · Nelly Joseph‐Mathurin, Jorge J. Llibre‐Guerra, et al. · Annals of Neurology · 47
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Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)
2023 · Nicole S. McKay, Brian A. Gordon, et al. · Nature Neuroscience · 44
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Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease
2024 · Olivia Wagemann, Haiyan Liu, et al. · JAMA Neurology · 37
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Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer’s disease
2024 · Anna Hofmann, Lisa M. Häsler, et al. · Nature Communications · 34
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APOE ε4 genotype, amyloid-β, and sex interact to predict tau in regions of high APOE mRNA expression
2022 · Aylin Dincer, Charles D. Chen, et al. · Science Translational Medicine · 34
γ-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS)
2024 · Stephanie A Schultz, Lei Liu, et al. · The Lancet Neurology · 33
Multiple Mechanisms for Processing Reward Uncertainty in the Primate Basal Forebrain
2016 · Noah M. Ledbetter, Charles D. Chen, et al. · Journal of Neuroscience · 33
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Temporal Correlation of CSF and Neuroimaging in the Amyloid-Tau-Neurodegeneration Model of Alzheimer Disease
2021 · Anna H. Boerwinkle, Julie K. Wisch, et al. · Neurology · 28
Comparing amyloid-β plaque burden with antemortem PiB PET in autosomal dominant and late-onset Alzheimer disease
2021 · Charles D. Chen, Nelly Joseph-Mathurin, et al. · Acta Neuropathologica · 27
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Comparison of cerebrospinal fluid, plasma and neuroimaging biomarker utility in Alzheimer’s disease
2024 · Karin L Meeker, Patrick H Luckett, et al. · Brain Communications · 25
Longitudinal head-to-head comparison of 11C-PiB and 18F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer’s disease
2023 · Charles D. Chen, Austin McCullough, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 22
Investigating Tau and Amyloid Tracer Skull Binding in Studies of Alzheimer Disease
2022 · Shaney Flores, Charles D. Chen, et al. · Journal of Nuclear Medicine · 21
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Ante‐ and postmortem tau in autosomal dominant and late‐onset Alzheimer’s disease
2020 · Charles D. Chen, Timothy R. Holden, et al. · Annals of Clinical and Translational Neurology · 19
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Intracranial internal carotid artery calcification is not predictive of future cognitive decline
2022 · Farzaneh Rahmani, Marina Nguyen, et al. · Alzheimer s Research & Therapy · 17
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Presenilin‐1 mutation position influences amyloidosis, small vessel disease, and dementia with disease stage
2024 · Nelly Joseph‐Mathurin, Rebecca L. Feldman, et al. · Alzheimer s & Dementia · 16
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Validity Assessment of an Automated Brain Morphometry Tool for Patients with De Novo Memory Symptoms
2023 · F. Rahmani, S. Jindal, et al. · American Journal of Neuroradiology · 16
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Deconstructing pathological tau by biological process in early stages of Alzheimer disease: a method for quantifying tau spatial spread in neuroimaging
2024 · Stephanie Doering, Austin McCullough, et al. · EBioMedicine · 14
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Spatial extent as a sensitive amyloid‐PET metric in preclinical Alzheimer's disease
2024 · Michelle E. Farrell, Emma G. Thibault, et al. · Alzheimer s & Dementia · 12
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Novel CSF tau biomarkers can be used for disease staging of sporadic Alzheimer’s
2023 · Gemma Salvadó, Kanta Horie, et al. · Alzheimer s & Dementia · 12
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Works count: 68
Citation count: 1,644
H-index: 19
I10-index: 28
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