Author

Hirohide Nambu

Institution: Shionogi (Japan)

Observed institutions: Tokyo Medical and Dental University, Merck & Co., Inc., Rahway, NJ, USA (United States), Shionogi (Japan), The University of Tokyo

OpenAlex ID: A5086371981

In vitro and in vivo pharmacological characterization of J-113397, a potent and selective non-peptidyl ORL1 receptor antagonist

2000 · Satoshi Ozaki, Hiroshi Kawamoto, et al. · European Journal of Pharmacology · 167

Anatomical and histological profiling of orphan G-protein-coupled receptor expression in gastrointestinal tract of C57BL/6J mice

2009 · Junko Ito, Masahiko Ito, et al. · Cell and Tissue Research · 96

Characterization of metabolic phenotypes of mice lacking GPR61, an orphan G-protein coupled receptor

2011 · Hirohide Nambu, Miyuki Fukushima, et al. · Life Sciences · 38

An insurmountable NPY Y5 receptor antagonist exhibits superior anti-obesity effects in high-fat diet-induced obese mice

2018 · Yumiko Fukasaka, Hirohide Nambu, et al. · Neuropeptides · 24

Molecular cloning of homologs of RAS and RHO1 genes from Cryptococcus neoformans

1999 · Ken-ichi Tanaka, Hirohide Nambu, et al. · Yeast · 19

ACC2 Deletion Enhances IMCL Reduction Along With Acetyl-CoA Metabolism and Improves Insulin Sensitivity in Male Mice

2018 · Hiroyuki Takagi, Tatsuya Ikehara, et al. · Endocrinology · 18

Hit to lead SAR study on benzoxazole derivatives for an NPY Y5 antagonist

2012 · Naoki Omori, Naoki Kouyama, et al. · Bioorganic & Medicinal Chemistry Letters · 17

In vitro inhibitory effects of J-113397 on nociceptin/orphanin FQ-stimulated [35S]GTPγS binding to mouse brain

2001 · Daisuke Ichikawa, Satoshi Ozaki, et al. · Neuroreport · 16

Diacylglycerol acyltransferase 1/2 inhibition induces dysregulation of fatty acid metabolism and leads to intestinal barrier failure and diarrhea in mice

2020 · Kosuke Takemoto, Yumiko Fukasaka, et al. · Physiological Reports · 13

Identification of a novel benzimidazole derivative as a highly potent NPY Y5 receptor antagonist with an anti-obesity profile

2012 · Yuusuke Tamura, Kyouhei Hayashi, et al. · Bioorganic & Medicinal Chemistry Letters · 10

Cloning and characterization of the rhesus monkey nociceptin/orphanin FQ receptor

2009 · Kazumi Koga, Daisuke Ichikawa, et al. · Genes & Genetic Systems · 4

A Novel Cell-Free System for Peptide Synthesis Driven by Pyridine

1998 · Itaru Nitta, Hirohide Nambu, et al. · Biological Chemistry · 1

Works count: 12

Citation count: 423

H-index: 10

I10-index: 10