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Author

Kyle M. Stiers

Observed names: K. Stiers, K.M. Stiers, Kyle Stiers, Stiers, Kyle, Stiers, Kyle M., Stiers, Kyle Matthew
ORCID: 0000-0001-5542-022X
Observed ORCID: 0000-0001-5542-022X
OpenAlex ID: A5086572161
The Metabolic Map into the Pathomechanism and Treatment of PGM1-CDG
2019 · Silvia Radenkovic, Matthew J. Bird, et al. · The American Journal of Human Genetics · 79
Structure, biochemistry, and gene expression patterns of the proline biosynthetic enzyme pyrroline-5-carboxylate reductase (PYCR), an emerging cancer therapy target
2021 · Alexandra N. Bogner, Kyle M. Stiers, et al. · Amino Acids · 59
Compromised Catalysis and Potential Folding Defects in in Vitro Studies of Missense Mutants Associated with Hereditary Phosphoglucomutase 1 Deficiency
2014 · Yingying Lee, Kyle M. Stiers, et al. · Journal of Biological Chemistry · 50
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Fourth Report on Chicken Genes and Chromosomes 2022
2022 · Jacqueline Smith, James M. Alfieri, et al. · Cytogenetic and Genome Research · 49
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Biology, Mechanism, and Structure of Enzymes in the α- d -Phosphohexomutase Superfamily
2017 · Kyle M. Stiers, Andrew G. Muenks, et al. · Advances in protein chemistry and structural biology · 48
Sequence-structure relationships, expression profiles, and disease-associated mutations in the paralogs of phosphoglucomutase 1
2017 · Andrew G. Muenks, Kyle M. Stiers, et al. · PLoS ONE · 28
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Induced Structural Disorder as a Molecular Mechanism for Enzyme Dysfunction in Phosphoglucomutase 1 Deficiency
2016 · Kyle M. Stiers, Bailee N. Kain, et al. · Journal of Molecular Biology · 25
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Structure and characterization of a class 3B proline utilization A: Ligand-induced dimerization and importance of the C-terminal domain for catalysis
2017 · David A. Korasick, Thameesha T. Gamage, et al. · Journal of Biological Chemistry · 24
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A Hotspot for Disease-Associated Variants of Human PGM1 Is Associated with Impaired Ligand Binding and Loop Dynamics
2018 · Kyle M. Stiers, Lesa J. Beamer · Structure · 22
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Trapping conformational states of a flavin-dependent N-monooxygenase in crystallo reveals protein and flavin dynamics
2020 · Ashley C. Campbell, Kyle M. Stiers, et al. · Journal of Biological Chemistry · 18
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Asp263 missense variants perturb the active site of human phosphoglucomutase 1
2017 · Kyle M. Stiers, Abigail C. Graham, et al. · FEBS Journal · 14
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Structural basis for the stereospecific inhibition of the dual proline/hydroxyproline catabolic enzyme ALDH4A1 by trans‐4‐hydroxy‐L‐proline
2021 · Alexandra N. Bogner, Kyle M. Stiers, et al. · Protein Science · 13
Inhibitory Evaluation of αPMM/PGM from Pseudomonas aeruginosa: Chemical Synthesis, Enzyme Kinetics, and Protein Crystallographic Study
2019 · Jian-She Zhu, Kyle M. Stiers, et al. · The Journal of Organic Chemistry · 13
Synthesis, Derivatization, and Structural Analysis of Phosphorylated Mono-, Di-, and Trifluorinated d -Gluco-heptuloses by Glucokinase: Tunable Phosphoglucomutase Inhibition
2019 · Jian-She Zhu, Kyle M. Stiers, et al. · ACS Omega · 10
Structural and dynamical description of the enzymatic reaction of a phosphohexomutase
2019 · Kyle M. Stiers, Abigail C. Graham, et al. · Structural Dynamics · 8
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Cautionary Tale of Using Tris(alkyl)phosphine Reducing Agents with NAD + -Dependent Enzymes
2020 · Sagar M. Patel, Thomas G. Smith, et al. · Biochemistry · 7
Assessment and Impacts of Phosphorylation on Protein Flexibility of the α-d-Phosphohexomutases
2018 · Kyle M. Stiers, Lesa J. Beamer · Methods in enzymology on CD-ROM/Methods in enzymology · 7
Phosphorylation-Dependent Effects on the Structural Flexibility of Phosphoglucosamine Mutase from Bacillus anthracis
2017 · Kyle M. Stiers, Jia Xu, et al. · ACS Omega · 6
Synchrotron-based macromolecular crystallography module for an undergraduate biochemistry laboratory course
2016 · Kyle M. Stiers, Christopher B. Lee, et al. · Journal of Applied Crystallography · 5
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Kinetics of human pyrroline-5-carboxylate reductase in l-thioproline metabolism
2021 · Sagar M. Patel, Javier Seravalli, et al. · Amino Acids · 4
A missense variant remote from the active site impairs stability of human phosphoglucomutase 1
2020 · Kyle M. Stiers, Reed P. Hansen, et al. · Journal of Inherited Metabolic Disease · 4
PGM1 deficiency disrupts sarcomere and mitochondrial function in a stem-cell cardiomyocyte model
2025 · Silvia Radenkovic, Graeme Preston, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
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Effects of the T337M and G391V disease-related variants on human phosphoglucomutase 1: structural disruptions large and small
2022 · Kyle M. Stiers, Luckio F. Owuocha, et al. · Acta Crystallographica Section F Structural Biology Communications · 1
PGM1 deficiency is linked to sarcomeric and mitochondrial dysfunction in patient-derived iPSC-cardiomyocytes
2026 · Silvia Radenkovic, Graeme Preston, et al. · Journal of Translational Medicine
PGM1 deficiency is linked to sarcomeric and mitochondrial dysfunction in patient-derived iPSC-cardiomyocytes
2026 · Radenkovic, Silvia, Preston, Graeme, et al. · Figshare
Works count: 43
Citation count: 496
H-index: 13
I10-index: 14
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