Author

Nigel D. F. Grindley

Observed names: N D Grindley, N Grindley, N. D. F. GRINDLEY, N. D. F. Grindley, N. D. Grindley, N. Grindley, N.D. Grindley, N.D.F Grindley, N.D.F. Grindley, Nigel D. Grindley, Nigel D.F Grindley, Nigel D.F. Grindley

Institution: Yale University

Observed institutions: American Cancer Society, National Institutes of Health, Howard Hughes Medical Institute, York College, City University of New York, University of Sussex, University of Pittsburgh, City University of New York, Yale University, Public Health England, Queens University of Charlotte, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Environmental Health Sciences, Queens College, Carnegie Mellon University, University of Glasgow, University of California, Berkeley, Stanford University

OpenAlex ID: A5086740949

Mechanisms of Site-Specific Recombination

2006 · Nigel D.F. Grindley, Katrine L. Whiteson, et al. · Annual Review of Biochemistry · 817

The 3′‐5′ exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction.

1991 · V. Derbyshire, N. D. Grindley, et al. · The EMBO Journal · 272

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Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli.

1990 · A.H. Polesky, T.A. Steitz, et al. · Journal of Biological Chemistry · 260

Method for determining whether a gene of Escherichia coli is essential: application to the polA gene

1984 · C M Joyce, N D Grindley · Journal of Bacteriology · 252

Conformational transitions in DNA polymerase I revealed by single-molecule FRET

2009 · Yusdi Santoso, Catherine M. Joyce, et al. · Proceedings of the National Academy of Sciences · 248

Transpositional Recombination in Prokaryotes

1985 · Nigel D. F. Grindley, Randall R. Reed · Annual Review of Biochemistry · 219

A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides

1998 · Mekbib Astatke, Kimmie Ng, et al. · Proceedings of the National Academy of Sciences · 214

Side chains involved in catalysis of the polymerase reaction of DNA polymerase I from Escherichia coli.

1992 · A.H. Polesky, M.E. Dahlberg, et al. · Journal of Biological Chemistry · 191

Transposon-mediated site-specific recombination in vitro: DNA cleavage and protein-DNA linkage at the recombination site

1981 · R.R. Reed, N.D.F. Grindley · Cell · 175

Nucleotide sequence of the Escherichia coli polA gene and primary structure of DNA polymerase I.

1982 · C.M. Joyce, W.S. Kelley, et al. · Journal of Biological Chemistry · 171

Construction of a plasmid that overproduces the large proteolytic fragment (Klenow fragment) of DNA polymerase I of Escherichia coli.

1983 · C M Joyce, N D Grindley · Proceedings of the National Academy of Sciences · 167

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Molecular Studies of R Factor Compatibility Groups

1973 · N. D. F. Grindley, G. O. Humphreys, et al. · Journal of Bacteriology · 156

Transposon-mediated site-specific recombination: Identification of three binding sites for resolvase at the res sites of γδ and Tn 3

1982 · N Grindley · Cell · 151

IS1 insertion generates duplication of a nine base pair sequence at its target site

1978 · Nigel D.F. Grindley · Cell · 144

Fingers-Closing and Other Rapid Conformational Changes in DNA Polymerase I (Klenow Fragment) and Their Role in Nucleotide Selectivity

2008 · Catherine M. Joyce, Olga Potapova, et al. · Biochemistry · 130

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Structure of a Synaptic γδ Resolvase Tetramer Covalently Linked to Two Cleaved DNAs

2005 · Weikai Li, Satwik Kamtekar, et al. · Science · 128

Sequence Analysis at IS1 Insertion Sites: Models for Transposition

1979 · N. D. F. Grindley, D. J. Sherratt · Cold Spring Harbor Symposia on Quantitative Biology · 128

Genetic and DNA sequence analysis of the kanamycin resistance transposon Tn903.

1980 · N D Grindley, C M Joyce · Proceedings of the National Academy of Sciences · 121

The Movement of Tn3‐Like Elements: Transposition and Cointegrate Resolution

2007 · Nigel D. F. Grindley · Wiley eBooks · 120

Use of 2-Aminopurine Fluorescence To Examine Conformational Changes during Nucleotide Incorporation by DNA Polymerase I (Klenow Fragment)

2003 · Vandana Purohit, Nigel D. F. Grindley, et al. · Biochemistry · 120

Deoxynucleoside Triphosphate and Pyrophosphate Binding Sites in the Catalytically Competent Ternary Complex for the Polymerase Reaction Catalyzed by DNA Polymerase I (Klenow Fragment)

1995 · Mekbib Astatke, Nigel D.F. Grindley, et al. · Journal of Biological Chemistry · 111

A simple and efficient procedure for saturation mutagenesis using mixed oligodeoxynucleotides

1986 · Keith M. Derbyshire, Joseph J. Salvo, et al. · Gene · 111

How E. coli DNA polymerase I (klenow fragment) distinguishes between deoxy- and dideoxynucleotides

1998 · Mekbib Astatke, Nigel D.F Grindley, et al. · Journal of Molecular Biology · 109

The crystal structure of the catalytic domain of the site-specific recombination enzyme γδ resolvase at 2.7 Å resolution

1990 · Mark R. Sanderson, Paul S. Freemont, et al. · Cell · 109

R factor compatibility groups

1972 · N. D. F. Grindley, June N. Grindley, et al. · Molecular and General Genetics MGG · 106

Works count: 132

Citation count: 8,256

H-index: 52

I10-index: 103