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Hien Tran Zhao

Observed names: Hien T Zhao, Hien T. Zhao, Hien Zhao, Hien T Zhao
ORCID: 0009-0000-0904-8201
Observed ORCID: 0009-0000-0904-8201
OpenAlex ID: A5086840387
LRRK2 Antisense Oligonucleotides Ameliorate α-Synuclein Inclusion Formation in a Parkinson’s Disease Mouse Model
2017 · Hien Tran Zhao, Neena John, et al. · Molecular Therapy — Nucleic Acids · 212
PMP22 antisense oligonucleotides reverse Charcot-Marie-Tooth disease type 1A features in rodent models
2017 · Hien Tran Zhao, Sagar Damle, et al. · Journal of Clinical Investigation · 162
α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson’s disease
2021 · Tracy A. Cole, Hien Zhao, et al. · JCI Insight · 151
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Antisense oligonucleotides extend survival of prion-infected mice
2019 · Gregory J. Raymond, Hien Tran Zhao, et al. · JCI Insight · 146
Oligonucleotide therapy mitigates disease in spinocerebellar ataxia type 3 mice
2018 · Hayley S. McLoughlin, Lauren R. Moore, et al. · Annals of Neurology · 144
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Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints
2020 · Eric Vallabh Minikel, Hien T Zhao, et al. · Nucleic Acids Research · 141
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The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration
2020 · Paymaan Jafar-nejad, Berit Powers, et al. · Nucleic Acids Research · 123
LRRK2 and Rab10 coordinate macropinocytosis to mediate immunological responses in phagocytes
2020 · Zhiyong Liu, Enquan Xu, et al. · The EMBO Journal · 90
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Characterization of the Prion Protein Binding Properties of Antisense Oligonucleotides
2019 · Andrew G Reidenbach, Eric Vallabh Minikel, et al. · Biomolecules · 81
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Suppression of proteolipid protein rescues Pelizaeus–Merzbacher disease
2020 · Matthew S. Elitt, Lilianne Barbar, et al. · Nature · 75
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Characterization of the structure and control of the blood-nerve barrier identifies avenues for therapeutic delivery
2023 · Liza Malong, Ilaria Napoli, et al. · Developmental Cell · 59
A single-cell map of antisense oligonucleotide activity in the brain
2023 · Meredith A Mortberg, Juliana E Gentile, et al. · Nucleic Acids Research · 54
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Antisense oligonucleotides selectively suppress target RNA in nociceptive neurons of the pain system and can ameliorate mechanical pain
2017 · Apoorva Mohan, Bethany Fitzsimmons, et al. · Pain · 44
Antisense oligonucleotide–mediated MSH3 suppression reduces somatic CAG repeat expansion in Huntington’s disease iPSC–derived striatal neurons
2025 · Emma L. Bunting, Jasmine Donaldson, et al. · Science Translational Medicine · 43
Regional variability and genotypic and pharmacodynamic effects on PrP concentration in the CNS
2022 · Meredith A Mortberg, Hien T Zhao, et al. · JCI Insight · 25
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An Antisense Oligonucleotide Leads to Suppressed Transcription of Hdac2 and Long-Term Memory Enhancement
2020 · Shane G. Poplawski, Krassimira A. Garbett, et al. · Molecular Therapy — Nucleic Acids · 21
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SARM1 activation induces reversible mitochondrial dysfunction and can be prevented in human neurons by antisense oligonucleotides
2025 · Andrea Loreto, Kaitlyn M.L. Cramb, et al. · Neurobiology of Disease · 14
Snca targeted antisense oligonucleotides mediate progression of pathological deposition in alpha synuclein rodent transmission models of Parkinson’s disease (P6.239)
2016 · Tracy Cole, Katrina Paumier, et al. · Neurology · 14
LRRK2-targeting antisense oligonucleotide in Parkinson’s disease: a phase 1 randomized controlled trial
2026 · Omar S. Mabrouk, Ben Tichler, et al. · Nature Medicine · 10
Alpha-synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson’s disease
2019 · Tracy A. Cole, Hien Zhao, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 10
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Antisense oligonucleotides directed against App and Rab5 normalized endosomal Rab activity and reversed DS‐AD‐linked degenerative phenotypes in the Dp16 mouse model of Down syndrome
2025 · Xu‐Qiao Chen, Xinxin Zuo, et al. · Alzheimer s & Dementia · 9
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Cellular and subcellular localization of Rab10 and phospho-T73 Rab10 in the mouse and human brain
2023 · Vijay Singh, Marissa A. Menard, et al. · Acta Neuropathologica Communications · 8
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PrP turnover in vivo and the time to effect of prion disease therapeutics
2026 · Taylor L Corridon, Jill O’Moore, et al. · PLoS Pathogens · 7
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Translational control in the spinal cord regulates gene expression and pain hypersensitivity in the chronic phase of neuropathic pain
2026 · Kevin C. Lister, Calvin Wong, et al. · eLife · 6
Transient Acute Neuronal Activation Response Caused by High Concentrations of Oligonucleotides in the Cerebral Spinal Fluid
2025 · Mariana Bravo Hernandez, Curt Mazur, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 4
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Works count: 41
Citation count: 1,670
H-index: 16
I10-index: 20
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