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Hwi‐Ho Lee

Kaempferol 7-O-β-D-glucoside isolated from the leaves of Cudrania tricuspidata inhibits LPS-induced expression of pro-inflammatory mediators through inactivation of NF-κB, AP-1, and JAK-STAT in RAW 264.7 macrophages
2018 · Seung-Bin Lee, Ji-Sun Shin, et al. · Chemico-Biological Interactions · 68
Biflorin, Isolated from the Flower Buds ofSyzygium aromaticumL., Suppresses LPS-Induced Inflammatory Mediators via STAT1 Inactivation in Macrophages and Protects Mice from Endotoxin Shock
2016 · Hwi-Ho Lee, Ji-Sun Shin, et al. · Journal of Natural Products · 49
Fulgidic Acid Isolated from the Rhizomes of Cyperus rotundus Suppresses LPS-Induced iNOS, COX-2, TNF-α, and IL-6 Expression by AP-1 Inactivation in RAW264.7 Macrophages
2015 · Ji-Sun Shin, Yujin Hong, et al. · Biological and Pharmaceutical Bulletin · 45
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Repurposing mosloflavone/5,6,7-trimethoxyflavone-resveratrol hybrids: Discovery of novel p38-α MAPK inhibitors as potent interceptors of macrophage-dependent production of proinflammatory mediators
2019 · Ahmed H.E. Hassan, Sung Yeun Yoo, et al. · European Journal of Medicinal Chemistry · 44
EGFR inhibitors from cancer to inflammation: Discovery of 4-fluoro-N-(4-(3-(trifluoromethyl)phenoxy)pyrimidin-5-yl)benzamide as a novel anti-inflammatory EGFR inhibitor
2019 · Ahmed Elkamhawy, Ahmed H.E. Hassan, et al. · Bioorganic Chemistry · 42
α‐Solanine Isolated FromSolanum TuberosumL. cv Jayoung Abrogates LPS‐Induced Inflammatory Responses Via NF‐κB Inactivation in RAW 264.7 Macrophages and Endotoxin‐Induced Shock Model in Mice
2016 · Ji‐Sun Shin, Kyoung‐Goo Lee, et al. · Journal of Cellular Biochemistry · 41
Anti-inflammatory potential of Patrineolignan B isolated from Patrinia scabra in LPS-stimulated macrophages via inhibition of NF-κB, AP-1, and JAK/STAT pathways
2020 · Hwi-Ho Lee, Eungyeong Jang, et al. · International Immunopharmacology · 40
Patriscabrin F from the roots of Patrinia scabra attenuates LPS-induced inflammation by downregulating NF-κB, AP-1, IRF3, and STAT1/3 activation in RAW 264.7 macrophages
2020 · Ji-Sun Shin, Shin-Young Kang, et al. · Phytomedicine · 30
α-Chaconine isolated from a Solanum tuberosum L. cv Jayoung suppresses lipopolysaccharide-induced pro-inflammatory mediators via AP-1 inactivation in RAW 264.7 macrophages and protects mice from endotoxin shock
2015 · Kyoung-Goo Lee, Suel-Gie Lee, et al. · Chemico-Biological Interactions · 27
Immunostimulatory Effects of Live Lactobacillus sakei K040706 on the CYP-Induced Immunosuppression Mouse Model
2020 · Seo-Yeon Kim, Ji-Sun Shin, et al. · Nutrients · 25
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The Anti-Proliferative Activity of the Hybrid TMS-TMF-4f Compound Against Human Cervical Cancer Involves Apoptosis Mediated by STAT3 Inactivation
2019 · Joo Young Hong, Kyung-Sook Chung, et al. · Cancers · 24
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3ʹ,4ʹ-Dihydroxyflavone mitigates inflammatory responses by inhibiting LPS and TLR4/MD2 interaction
2022 · Hwi-Ho Lee, Ji-Sun Shin, et al. · Phytomedicine · 23
Mosloflavone-Resveratrol Hybrid TMS-HDMF-5z Exhibits Potent In Vitro and In Vivo Anti-Inflammatory Effects Through NF-κB, AP-1, and JAK/STAT Inactivation
2022 · Seo-Yeon Kim, Ahmed H.E. Hassan, et al. · Frontiers in Pharmacology · 19
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A novel mPGES-1 inhibitor alleviates inflammatory responses by downregulating PGE2 in experimental models
2019 · Hwi-Ho Lee, YoonHyoung Moon, et al. · Prostaglandins & Other Lipid Mediators · 19
A host non-coding RNA, nc886, plays a pro-viral role by promoting virus trafficking to the nucleus
2022 · Enkhjin Saruuldalai, Jiyoung Park, et al. · Molecular Therapy — Oncolytics · 18
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Identification and structure activity relationship of novel flavone derivatives that inhibit the production of nitric oxide and PGE2 in LPS-induced RAW 264.7 cells
2017 · Ji-Young An, Hwi-Ho Lee, et al. · Bioorganic & Medicinal Chemistry Letters · 18
p-Coumaroyl Anthocyanin Mixture Isolated from Tuber Epidermis of Solanum tuberosum Attenuates Reactive Oxygen Species and Pro-inflammatory Mediators by Suppressing NF-κB and STAT1/3 Signaling in LPS-Induced RAW264.7 Macrophages
2017 · Hwi-Ho Lee, Suel-Gie Lee, et al. · Biological and Pharmaceutical Bulletin · 18
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Inhibitory effects of triarylpyrazole derivatives on LPS-induced nitric oxide and PGE2 productions in murine RAW 264.7 macrophages
2019 · Mahmoud M. Gamal El-Din, Mohammed I. El-Gamal, et al. · Bioorganic & Medicinal Chemistry Letters · 15
Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl) ethenyl]-quinazoline induces G2/M cell cycle arrest through the activation of ATM/ATR in human cervical carcinoma HeLa cells
2015 · JONG-YUN KIM, HYE-EUN CHOI, et al. · Oncology Reports · 14
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Early stage ultraviolet irradiation damage to skin collagen can be suppressed by HPA axis control via controlled CYP11B
2022 · Hye-Sun Lim, Seung Hoon Lee, et al. · Biomedicine & Pharmacotherapy · 10
Improved tumor-suppressive effect of OZ-001 combined with cisplatin mediated by mTOR/p70S6K and STAT3 inactivation in A549 human lung cancer cells
2021 · Jeong-Hun Lee, Kyung-Sook Chung, et al. · Biomedicine & Pharmacotherapy · 7
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In vitro and in vivo neuroprotective effect of novel mPGES-1 inhibitor in animal model of Parkinson’s disease
2022 · Seyoung Yang, Eugene Huh, et al. · Bioorganic & Medicinal Chemistry Letters · 5
Adenovirus expressing nc886, an anti-interferon and anti-apoptotic non-coding RNA, is an improved gene delivery vector
2024 · Enkhjin Saruuldalai, Hwi-Ho Lee, et al. · Molecular Therapy — Nucleic Acids · 2
A Novel Phenylsulfonamide Ameliorates the Cognitive Impairment in Mice Induced by Scopolamine
2018 · Sun Young Kim, Da Woon Jung, et al. · Bulletin of the Korean Chemical Society · 1
Single-cell RNA sequencing of nc886, a non-coding RNA transcribed by RNA polymerase III, with a primer spike-in strategy
2024 · Gyeong-Jin Shin, Byung-Han Choi, et al. · PLoS ONE
Works count: 26
Citation count: 604
H-index: 17
I10-index: 20
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