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Andrea J. Bernhardy
Observed names:
A Bernhardy,
Andrea Bernhardy
Institution:
Fox Chase Cancer Center
Observed institutions:
Brigham and Women's Hospital,
Fox Chase Cancer Center,
Beth Israel Deaconess Medical Center,
Harvard University
OpenAlex ID:
A5087165116
Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans
2010
·
Giulio Genovese
, David J. Friedman
, et al.
·
Science
·
2,025
CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer
2016
·
Shawn F. Johnson
, Cristina Cruz
, et al.
·
Cell Reports
·
287
PDF
The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin
2016
·
Yifan Wang
, Andrea J. Bernhardy
, et al.
·
Cancer Research
·
269
Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance
2013
·
Neil Johnson
, Shawn F. Johnson
, et al.
·
Proceedings of the National Academy of Sciences
·
265
The APOL1 Genotype of African American Kidney Transplant Recipients Does Not Impact 5-Year Allograft Survival
2012
·
B.T Lee
, V Kumar
, et al.
·
American Journal of Transplantation
·
181
PDF
A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9
2010
·
Giulio Genovese
, Stephen J. Tonna
, et al.
·
Kidney International
·
171
Genetic Variation in APOL1 Associates with Younger Age at Hemodialysis Initiation
2011
·
Zahra Kanji
, Camille E. Powe
, et al.
·
Journal of the American Society of Nephrology
·
117
RING domain–deficient BRCA1 promotes PARP inhibitor and platinum resistance
2016
·
Yifan Wang
, John J. Krais
, et al.
·
Journal of Clinical Investigation
·
106
PDF
BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance
2018
·
Joseph Nacson
, John J. Krais
, et al.
·
Cell Reports
·
98
Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells
2018
·
Katherine Sullivan-Reed
, Elisabeth Bolton-Gillespie
, et al.
·
Cell Reports
·
91
PDF
RNF168-mediated localization of BARD1 recruits the BRCA1-PALB2 complex to DNA damage
2021
·
John J. Krais
, Yifan Wang
, et al.
·
Nature Communications
·
65
PDF
BRCA1 intronic Alu elements drive gene rearrangements and PARP inhibitor resistance
2019
·
Yifan Wang
, Andrea J. Bernhardy
, et al.
·
Nature Communications
·
59
PDF
BRCA1 Mutational Complementation Induces Synthetic Viability
2020
·
Joseph Nacson
, Daniela Di Marcantonio
, et al.
·
Molecular Cell
·
58
PDF
Discovery of new glomerular disease–relevant genes by translational profiling of podocytes in vivo
2014
·
Ivica Grgic
, Andreas F. Hofmeister
, et al.
·
Kidney International
·
45
Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities
2023
·
John J. Krais
, David J. Glass
, et al.
·
Nature Communications
·
30
PDF
Amplification of the Mutation-Carrying BRCA2 Allele Promotes RAD51 Loading and PARP Inhibitor Resistance in the Absence of Reversion Mutations
2019
·
Pyoung Hwa Park
, Tomomi M. Yamamoto
, et al.
·
Molecular Cancer Therapeutics
·
29
RNF168-Mediated Ubiquitin Signaling Inhibits the Viability of BRCA1 -Null Cancers
2020
·
John J. Krais
, Yifan Wang
, et al.
·
Cancer Research
·
26
BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance
2018
·
Joseph Nacson
, John J. Krais
, et al.
·
Cell Reports
·
26
PDF
Copy Number Variation at the APOL1 Locus
2015
·
Rupam Ruchi
, Giulio Genovese
, et al.
·
PLoS ONE
·
21
PDF
Reduced PAK1 activity sensitizes FA/BRCA-proficient breast cancer cells to PARP inhibition
2016
·
Olga Villamar Cruz
, Tatiana Y. Prudnikova
, et al.
·
Oncotarget
·
18
PDF
PALB2 and 53BP1 govern post-resection homologous recombination DNA repair
2025
·
Yifan Wang
, Yan Coulombe
, et al.
·
Molecular Cell
·
3
Abstract AP30: BRCA1 INTRON RETENTION GENERATES TRUNCATED PROTEINS THAT AVOID BRCT MUTATION MISFOLDING AND PROMOTE PARP INHIBITOR RESISTANCE
2019
·
Yifan Wang
, Andrea J. Bernhardy
, et al.
·
Clinical Cancer Research
·
1
Abstract A23: BRCA1 mutations in the BRCT domain can be removed through alternative splicing and induce PARP inhibitor resistance
2017
·
Yifan Wang
, Andrea J. Bernhardy
, et al.
·
Molecular Cancer Research
·
1
PALB2 and 53BP1 govern post-resection homologous recombination DNA repair
2025
·
Yifan Wang
, Yan Coulombe
, et al.
·
Molecular Cell
Data from Amplification of the Mutation-Carrying BRCA2 Allele Promotes RAD51 Loading and PARP Inhibitor Resistance in the Absence of Reversion Mutations
2023
·
Pyoung Hwa Park
, Tomomi M. Yamamoto
, et al.
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Works count:
63
Citation count:
3,991
H-index:
19
I10-index:
20
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