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Alejandro Méndez‐Mancilla

Observed names: A. Mendez-Mancilla, A. Méndez‐Mancilla, A., Méndez-Mancilla, Alejandro Mendez-Mancilla, Alejandro Méndez-Mancilla
ORCID: 0000-0002-2776-9229
Observed ORCID: 0000-0002-2776-9229
OpenAlex ID: A5089427638
Massively parallel Cas13 screens reveal principles for guide RNA design
2020 · Hans-Hermann Wessels, Alejandro Méndez-Mancilla, et al. · Nature Biotechnology · 410
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Prediction of on-target and off-target activity of CRISPR–Cas13d guide RNAs using deep learning
2023 · Hans-Hermann Wessels, Andrew Stirn, et al. · Nature Biotechnology · 132
Profiling the genetic determinants of chromatin accessibility with scalable single-cell CRISPR screens
2021 · Noa Liscovitch-Brauer, Antonino Montalbano, et al. · Nature Biotechnology · 107
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Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq
2022 · Hans-Hermann Wessels, Alejandro Méndez-Mancilla, et al. · Nature Methods · 79
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Transcriptome-wide Cas13 guide RNA design for model organisms and viral RNA pathogens
2021 · Xinyi Guo, Jahan A. Rahman, et al. · Cell Genomics · 79
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Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells
2021 · Alejandro Méndez-Mancilla, Hans-Hermann Wessels, et al. · Cell chemical biology · 67
RETRACTED: Transcriptome-scale RNA-targeting CRISPR screens reveal essential lncRNAs in human cells
2024 · Wen-Wei Liang, Simon Müller, et al. · Cell · 61
Precise RNA targeting with CRISPR–Cas13d
2025 · Sydney K. Hart, Simon Müller, et al. · Nature Biotechnology · 34
Differential expression profiles of circulating microRNAs in newborns associated to maternal pregestational overweight and obesity
2017 · A. Méndez‐Mancilla, V. Lima‐Rogel, et al. · Pediatric Obesity · 28
Increased levels of adipose tissue-resident Th17 cells in obesity associated with miR-326
2019 · Mariela Vega-Cárdenas, Edith E. Uresti-Rivera, et al. · Immunology Letters · 20
miRNAs in nutrition, obesity, and cancer: The biology of miRNAs in metabolic disorders and its relationship with cancer development
2017 · Verónica del Carmen Martínez‐Jiménez, Alejandro Méndez‐Mancilla, et al. · Molecular Nutrition & Food Research · 19
Changes in PPAR-γ Expression Are Associated with microRNA Profiles during Fetal Programming due to Maternal Overweight and Obesity
2021 · Noemí Gaytán-Pacheco, Victoria Lima-Rogel, et al. · Gynecologic and Obstetric Investigation · 12
Comprehensive dissection of cis-regulatory elements in a 2.8 Mb topologically associated domain in six human cancers
2025 · Christina M. Caragine, Victoria T. Le, et al. · Nature Communications · 9
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miR-21, miR-221, miR-29 and miR-34 are distinguishable molecular features of a metabolically unhealthy phenotype in young adults
2024 · Alejandro Méndez-Mancilla, Eneida Turiján-Espinoza, et al. · PLoS ONE · 8
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The inflammatory state of adipose tissue is not affected by the anti-inflammatory response of the A2a-adenosine system and miR-221/PTEN
2018 · J.D. Cortés-Garcia, M.J. Briones-Espinoza, et al. · The International Journal of Biochemistry & Cell Biology · 8
Retraction notice to: Transcriptome-scale RNA-targeting CRISPR screens reveal essential lncRNAs in human cells
2025 · Wen-Wei Liang, Simon Müller, et al. · Cell · 2
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Essential lncRNAs in the human transcriptome
2026 · Wen-Wei Liang, Simon J. Mueller, et al. · Cell Genomics
Supplementary Material for: Changes in PPAR-γ Expression Are Associated with microRNA Profiles during Fetal Programming due to Maternal Overweight and Obesity
2021 · N., Gaytán-Pacheco, V., Lima-Rogel, et al. · Figshare
Works count: 18
Citation count: 1,075
H-index: 12
I10-index: 12
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