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Mayako Yamazaki
Observed names:
M Yamazaki,
M. Yamazaki
Institution:
Astellas Pharma (Japan)
Observed institution:
Astellas Pharma (Japan)
ORCID:
0000-0002-1654-1851
Observed ORCID:
0000-0002-1654-1851
OpenAlex ID:
A5089779113
A novel glycine transporter-1 (GlyT1) inhibitor, ASP2535 (4-[3-isopropyl-5-(6-phenyl-3-pyridyl)-4H-1,2,4-triazol-4-yl]-2,1,3-benzoxadiazole), improves cognition in animal models of cognitive impairment in schizophrenia and Alzheimer's disease
2012
·
Katsuya Harada
, Kazuhiro Nakato
, et al.
·
European Journal of Pharmacology
·
60
Changes in brain somatostatin in memory-deficient rats: comparison with cholinergic markers
1995
·
N. Matsuoka
, M. Yamazaki
, et al.
·
Neuroscience
·
53
Novel 5-HT5A receptor antagonists ameliorate scopolamine-induced working memory deficit in mice and reference memory impairment in aged rats
2015
·
Mayako Yamazaki
, Mayuko Okabe
, et al.
·
Journal of Pharmacological Sciences
·
42
PDF
FK960 N-(4-acetyl-1-piperazinyl)-p-fluorobenzamide monohydrate ameliorates the memory deficits in rats through a novel mechanism of action.
1996
·
M Yamazaki
, N Matsuoka
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
38
ASP5736, a novel 5-HT5A receptor antagonist, ameliorates positive symptoms and cognitive impairment in animal models of schizophrenia
2014
·
Mayako Yamazaki
, Katsuya Harada
, et al.
·
European Neuropsychopharmacology
·
36
PDF
Effect of FR121196, a novel cognitive enhancer, on the memory impairment of rats in passive avoidance and radial arm maze tasks.
1992
·
N Matsuoka
, N Maeda
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
35
The Possible Role of Age-Related Increase in the Plasma Glucagon/Insulin Ratio in the Enhanced Hepatic Gluconeogenesis and Hyperglycemia in Genetically Diabetic (C57BL/KsJ-db/db) Mice
1994
·
Hiroshi Kodama
, Masataka Fujita
, et al.
·
The Japanese Journal of Pharmacology
·
32
FR121196, a potential antidementia drug, ameliorates the impaired memory of rat in the Morris water maze.
1995
·
M Yamazaki
, N Matsuoka
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
29
Fragment-Based Discovery of Pyrimido[1,2-b]indazole PDE10A Inhibitors
2018
·
Ayaka Chino
, Ryushi Seo
, et al.
·
Chemical and Pharmaceutical Bulletin
·
28
PDF
Novel benzimidazole derivatives as phosphodiesterase 10A (PDE10A) inhibitors with improved metabolic stability
2014
·
Ayaka Chino
, Naoyuki Masuda
, et al.
·
Bioorganic & Medicinal Chemistry
·
27
Effects of non-steroidal anti-inflammatory drugs on Aβ deposition in Aβ1–42 transgenic C. elegans
2009
·
Masahiko Morita
, Kazuhiko Osoda
, et al.
·
Brain Research
·
20
Effects of (+)-bicuculline, a GABAa receptor antagonist, on auditory steady state response in free-moving rats
2020
·
Mayako Yamazaki
, Sokichi Honda
, et al.
·
PLoS ONE
·
18
PDF
Functional mechanism of ASP5736, a selective serotonin 5-HT5A receptor antagonist with potential utility for the treatment of cognitive dysfunction in schizophrenia
2018
·
Mayako Yamazaki
, Noriyuki Yamamoto
, et al.
·
European Neuropsychopharmacology
·
13
PDF
Neurochemical and neuropharmacological characterization of ASP2905, a novel potent selective inhibitor of the potassium channel KCNH3
2017
·
Shinji Takahashi
, Kohei Inamura
, et al.
·
European Journal of Pharmacology
·
11
A Screening Concept Based on a Hypothesis Led to the Development of a Putative Cognitive Enhancer That Stimulates Penile Erection
1994
·
Noriaki Maeda
, Nobuya Matsuoka
, et al.
·
The Japanese Journal of Pharmacology
·
11
Synthesis, SAR study, and biological evaluation of novel 2,3-dihydro-1H-imidazo[1,2-a]benzimidazole derivatives as phosphodiesterase 10A inhibitors
2019
·
Ayaka Chino
, Shugo Honda
, et al.
·
Bioorganic & Medicinal Chemistry
·
10
5-HT5A Receptor Antagonist ASP5736 Ameliorates Several Abnormal Behaviors in an Fmr1-Targeted Transgenic Male Rat Model of Fragile X Syndrome
2022
·
Mayako Yamazaki
, Takatomo Arai
, et al.
·
The International Journal of Neuropsychopharmacology
·
8
PDF
Involvement of Raphe-Hippocampal Serotonergic and Septo-Hippocampal Cholinergic Mechanisms in the Penile Erection Induced by FR121196, a Putative Cognitive Enhancer
1995
·
Noriaki Maeda
, Nobuya Matsuoka
, et al.
·
The Japanese Journal of Pharmacology
·
4
ASP2905, a specific inhibitor of the potassium channel Kv12.2 encoded by the Kcnh3 gene, is psychoactive in mice
2019
·
Shinji Takahashi
, Ai Okamura
, et al.
·
Behavioural Brain Research
·
3
Functional mode of action of ASP5736, a selective 5-HT5A receptor antagonist for treatment of cognitive dysfunction in schizophrenia
2019
·
T.H. Svensson
, M. Yamazaki
, et al.
·
European Neuropsychopharmacology
·
1
Cognitive enhancing action of FR121196, a potential anti-dementia drug, and its mechanisms of action.
1994
·
Nobuya Matsuoka
, Noriaki Maeda
, et al.
·
The Japanese Journal of Pharmacology
·
1
PDF
Effect of FR121196, a novel cognitive enhancer, on memory impairment of nbM-lesioned and aged rats
1992
·
Mayako Yamazaki
, Noriaki Maeda
, et al.
·
The Japanese Journal of Pharmacology
·
1
PDF
The expression and pharmacological characterisation of human nNOS and eNOS
1998
·
Mayako Yamazaki
, Akiko Suzuki
, et al.
·
The Japanese Journal of Pharmacology
Pharmacological characterization of human 5-HT2C receptors expressed in Chinese hamster ovary cells
1997
·
Akiko Suzuki
, Shizuo Ao
, et al.
·
The Japanese Journal of Pharmacology
PDF
FK960 ameliorates the memory deficits in rats through a novel mechanism of action
1997
·
Mayako Yamazaki
, Nobuya Maisuoka
, et al.
·
The Japanese Journal of Pharmacology
PDF
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Works count:
29
Citation count:
481
H-index:
13
I10-index:
16
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