Author

Katrin Georgi

Observed name: Georgi, Katrin

Institutions: Janssen (Belgium), Merck KGaA, Darmstadt (Germany), Karolinska Institutet, Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Bayer (Germany), University of Tübingen

Observed institutions: Janssen (Belgium), Merck KGaA, Darmstadt (Germany), University of California System, Karolinska Institutet, EMD Serono, Inc. (United States), Merck Serono S.A. (Switzerland), Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Helmholtz Centre for Infection Research, Helmholtz Institute for Pharmaceutical Research Saarland, UC Davis Comprehensive Cancer Center, Merck Healthcare KGaA, Darmstadt (Germany), MilliporeSigma (United States), Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, Bayer (Germany), University of Tübingen, Ludwig-Maximilians-Universität München, University of California, Davis, Saarland University, The University of Texas Health Science Center at Houston

OpenAlex ID: A5090830971

Quantitative Profiling Method for Oxylipin Metabolome by Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry

2009 · Jun Yang, Kara Schmelzer, et al. · Analytical Chemistry · 309

Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways

2008 · Bora Inceoglu, Steven L. Jinks, et al. · Proceedings of the National Academy of Sciences · 188

Individual Variation in Lipidomic Profiles of Healthy Subjects in Response to Omega-3 Fatty Acids

2013 · Malin L. Nording, Jun Yang, et al. · PLoS ONE · 99

PDF

Serum oxylipin profiles in IgA nephropathy patients reflect kidney functional alterations

2012 · Angela M. Zivkovic, Jun Yang, et al. · Metabolomics · 84

Discovery of Potent, Orally Bioavailable, Small-Molecule Inhibitors of WNT Signaling from a Cell-Based Pathway Screen

2015 · Aurélie Mallinger, Simon Crumpler, et al. · Journal of Medicinal Chemistry · 82

PDF

Identification and Optimization of an Aminoalcohol-Carbazole Series with Antimalarial Properties

2013 · Jérôme Molette, Julie Routier, et al. · ACS Medicinal Chemistry Letters · 43

Altered Soluble Epoxide Hydrolase Gene Expression and Function and Vascular Disease Risk in the Stroke-Prone Spontaneously Hypertensive Rat

2007 · Mandi J. Corenblum, Vance E. Wise, et al. · Hypertension · 36

PDF

Multi-Well Array Culture of Primary Human Hepatocyte Spheroids for Clearance Extrapolation of Slowly Metabolized Compounds

2022 · Lena C. Preiss, Volker M. Lauschke, et al. · The AAPS Journal · 35

Considerations for Human ADME Strategy and Design Paradigm Shift(s) – An Industry White Paper

2022 · Graeme C. Young, Douglas K. Spracklin, et al. · Clinical Pharmacology & Therapeutics · 32

PDF

Crystalline Sponges as a Sensitive and Fast Method for Metabolite Identification: Application to Gemfibrozil and its Phase I and II Metabolites

2020 · Lara Rosenberger, Carolina von Essen, et al. · Drug Metabolism and Disposition · 27

PDF

Changes in PTGS1 and ALOX12 Gene Expression in Peripheral Blood Mononuclear Cells Are Associated with Changes in Arachidonic Acid, Oxylipins, and Oxylipin/Fatty Acid Ratios in Response to Omega-3 Fatty Acid Supplementation

2015 · Claire C. Berthelot, Shizuo George Kamita, et al. · PLoS ONE · 21

PDF

Comparison of Human Long-Term Liver Models for Clearance Prediction of Slowly Metabolized Compounds

2024 · Lena C. Preiss, Katrin Georgi, et al. · Drug Metabolism and Disposition · 14

PDF

Identification of Clinical Candidate M2698, a Dual p70S6K and Akt Inhibitor, for Treatment of PAM Pathway-Altered Cancers

2021 · Lizbeth DeSelm, Bayard Huck, et al. · Journal of Medicinal Chemistry · 14

Crystalline sponge affinity screening: A fast tool for soaking condition optimization without the need of X-ray diffraction analysis

2021 · Lara Rosenberger, Carolina von Essen, et al. · European Journal of Pharmaceutical Sciences · 12

Deconvolution of Cytochrome P450 Induction Mechanisms in HepaRG Nuclear Hormone Receptor Knockout Cells

2021 · Lena C. Preiss, Ruoqi Liu, et al. · Drug Metabolism and Disposition · 12

Increasing the Reuse of Protein Non-Naïve Nonhuman Primates in Pharmaceutical Drug Discovery and Development: An Overview and Industry Position on the Challenges and Benefits

2022 · Charles Mattis, Natalie Bratcher, et al. · International Journal of Toxicology · 11

Recommendations on the Use of Multiple Labels in Human Mass Balance Studies

2024 · Filip Cuyckens, Mette G. Hvenegaard, et al. · Drug Metabolism and Disposition · 8

PDF

Metabolic Profiling of S-praziquantel: Structure Elucidation Using the Crystalline Sponge Method in Combination with Mass Spectrometry and Nuclear Magnetic Resonance

2022 · Lara Rosenberger, Judith Jenniches, et al. · Drug Metabolism and Disposition · 7

PDF

Pharmacophore‐Based Design of Novel Oxadiazoles as Selective Sphingosine‐1‐phosphate (S1P) Receptor Agonists with in vivo Efficacy

2015 · Anna Quattropani, Wolfgang H. B. Sauer, et al. · ChemMedChem · 7

Non‐Labeled, Stable Labeled, or Radiolabelled Approaches for Provision of Intravenous Pharmacokinetics in Humans: A Discussion Piece

2023 · Graeme C. Young, Douglas K. Spracklin, et al. · Clinical Pharmacology & Therapeutics · 6

Discovery of Covalent Bruton's Tyrosine Kinase Inhibitors with Decreased CYP2C8 Inhibitory Activity

2021 · Hui Qiu, Zahid Ali, et al. · ChemMedChem · 2

Evobrutinib pathway to its major metabolite M463-2 and insights from a biotransformation and DDI perspective

2023 · Holger Scheible, Hanno Schieferstein, et al. · Xenobiotica · 1

PDF

Progress in deciphering the biological role of the human soluble epoxide hydrolase phosphatase activity

2008 · Christophe Morisseau, Pavel Aronov, et al. · The FASEB Journal · 1

CCDC 2051333: Experimental Crystal Structure Determination

2021 · Rosenberger, Lara, von Essen, Carolina, et al. · The Cambridge Structural Database

CCDC 2051288: Experimental Crystal Structure Determination

2021 · Rosenberger, Lara, von Essen, Carolina, et al. · The Cambridge Structural Database

Works count: 57

Citation count: 1,051

H-index: 13

I10-index: 16