Author

Louis N. Jungheim

Observed names: L N Jungheim, L. N. JUNGHEIM, L. N. Jungheim, L.N. Jungheim, Louis N Jungheim

Observed institutions: Eli Lilly (United States), University of Illinois Chicago, University of Rochester

OpenAlex ID: A5091614101

Crystal structure of the human PRMT5:MEP50 complex

2012 · Stephen Antonysamy, Zahid Bonday, et al. · Proceedings of the National Academy of Sciences · 386

1,3-Dipolar cycloaddition reactions of pyrazolidinium ylides with acetylenes. Synthesis of a new class of antibacterial agents

1987 · Louis N. Jungheim, Sandra K. Sigmund · The Journal of Organic Chemistry · 148

Inhibitors of two-component signal transduction systems: inhibition of alginate gene activation in Pseudomonas aeruginosa.

1993 · S Roychoudhury, N A Zielinski, et al. · Proceedings of the National Academy of Sciences · 105

Novel Lipoglycopeptides as Inhibitors of Bacterial Signal Peptidase I

2004 · Palaniappan Kulanthaivel, Adam J. Kreuzman, et al. · Journal of Biological Chemistry · 101

Design of Antitumor Prodrugs: Substrates for Antibody Targeted Enzymes

1994 · Louis N. Jungheim, Timothy A. Shepherd · Chemical Reviews · 92

Bicyclic pyrazolidinones, a new class of antibacterial agent based on the β-lactam model

1987 · Louis N Jungheim, Sandra K Sigmund, et al. · Tetrahedron Letters · 90

Synthesis of a taxane triene

1986 · Andrew S. Kende, Stephen. Johnson, et al. · Journal of the American Chemical Society · 90

1-(Arylthio)cyclopropanecarboxaldehydes. Conjunctive reagents for secoalkylation

1980 · Barry M. Trost, Louis N. Jungheim · Journal of the American Chemical Society · 71

Bicyclic pyrazolidinone antibacterial agents. Synthesis of side chain analogues of carbapenems PS-5 and thienamycin

1989 · Louis N. Jungheim · Tetrahedron Letters · 66

Site-specific prodrug activation by antibody-beta-lactamase conjugates: regression and long-term growth inhibition of human colon carcinoma xenograft models.

1993 · D L Meyer, L N Jungheim, et al. · PubMed · 62

A novel targeted delivery system utilizing a cephalosporin-oncolytic prodrug activated by an antibody β-lactamase conjugate for the treatment of cancer

1991 · Timothy A. Shepherd, Louis N. Jungheim, et al. · Bioorganic & Medicinal Chemistry Letters · 57

A 1,3-O- to -C-alkyl shift catalyzed by palladium

1980 · Barry M. Trost, Thomas A. Runge, et al. · Journal of the American Chemical Society · 56

Cyclohexyl-linked tricyclic isoxazoles are potent and selective modulators of the multidrug resistance protein (MRP1)

2005 · Bryan H. Norman, Peter A. Lander, et al. · Bioorganic & Medicinal Chemistry Letters · 55

Potent Human Immunodeficiency Virus Type 1 Protease Inhibitors That Utilize Noncoded d -Amino Acids as P 2 /P 3 Ligands

1996 · Louis N. Jungheim, Timothy A. Shepherd, et al. · Journal of Medicinal Chemistry · 41

Bicyclic pyrazolidinones, steric and electronic effects on antibacterial activity

1987 · Louis N Jungheim, Sandra K Sigmund, et al. · Tetrahedron Letters · 40

Preparation and characterization of a .beta.-lactamase-Fab' conjugate for the site-specific activation of oncolytic agents

1992 · Damon L. Meyer, Louis N. Jungheim, et al. · Bioconjugate Chemistry · 39

Synthesis, hydrolysis rates, supercomputer modeling, and antibacterial activity of bicyclic tetrahydropyridazinones

1991 · Louis N. Jungheim, Donald B. Boyd, et al. · Journal of Medicinal Chemistry · 39

Dual Inhibition of Human Rhinovirus 2A and 3C Proteases by Homophthalimides

1998 · Q. May Wang, Robert B. Johnson, et al. · Antimicrobial Agents and Chemotherapy · 37

Synthesis of a Cephalosporin-Doxorubicin Antitumor Prodrug: A Substrate for an Antibody-targeted Enzyme

1993 · Louis N. Jungheim, Timothy A. Shepherd, et al. · Heterocycles · 37

Synthesis of acylhydrazido-substituted cephems. Design of cephalosporin-vinca alkaloid prodrugs: substrates for an antibody targeted enzyme

1992 · Louis N. Jungheim, Timothy A. Shepherd, et al. · The Journal of Organic Chemistry · 33

Bicyclic pyrazolidinone antibacterial agents

1990 · L.N. Jungheim, R.J. Ternansky, et al. · Drugs of the Future · 32

Site-Specific Prodrug Activation by Antibody-.beta.-Lactamase Conjugates: Preclinical Investigation of the Efficacy and Toxicity of Doxorubicin Delivered by Antibody Directed Catalysis

1995 · Damon L. Meyer, Kevin L. Law, et al. · Bioconjugate Chemistry · 29

1,3-Dipolar cycloaddition reactions of pyrazolidinium ylides with vinyl sulfones. A regioselective synthesis of bicyclic pyrazolidinone antibacterial agents

1988 · Louis N. Jungheim, Charles J. Barnett, et al. · Tetrahedron · 29

Inhibition of human rhinovirus 3C protease by homophthalimides

1997 · Louis N. Jungheim, Jeffrey D. Cohen, et al. · Bioorganic & Medicinal Chemistry Letters · 24

Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions

2022 · Ben Gold, Jun Zhang, et al. · ACS Infectious Diseases · 23

Works count: 52

Citation count: 1,907

H-index: 24

I10-index: 30