Author

Yong-Kang Zhang

Observed names: Yongkang Zhang, Yong‐Kang Zhang

Institution: Yunnan Agricultural University

Observed institutions: Shanghai Medical College of Fudan University, Jishou University, National Academy of Sciences of Ukraine, Xuzhou Medical College, Shanghai Jiao Tong University, Yunnan Agricultural University, Huazhong Agricultural University, Fudan University, Oklahoma Medical Research Foundation, University of Florida, Hebei University of Science and Technology, University of Illinois Chicago, European Molecular Biology Laboratory, Zhongshan Hospital, Stanford Medicine, Weill Cornell Medicine, VMware (United States), Institute of Molecular Biology and Genetics, Stanford University

ORCID: 0000-0003-0013-639X

Observed ORCID: 0000-0003-0013-639X

OpenAlex ID: A5100739746

An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site

2007 · Fernando L. Rock, Weimin Mao, et al. · Science · 645

Therapeutic Potential of Boron-Containing Compounds

2009 · Stephen J Baker, Charles Z Ding, et al. · Future Medicinal Chemistry · 384

Discovery of a New Boron-Containing Antifungal Agent, 5-Fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the Potential Treatment of Onychomycosis

2006 · Stephen J. Baker, Yong-Kang Zhang, et al. · Journal of Medicinal Chemistry · 321

A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue

2017 · Ebere Sonoiki, Caroline L. Ng, et al. · Nature Communications · 145

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In Vitro Penetration of a Novel Oxaborole Antifungal (AN2690) Into the Human Nail Plate

2007 · Xiaoying Hui, Stephen J. Baker, et al. · Journal of Pharmaceutical Sciences · 117

Discovery of Novel Benzoxaborole-Based Potent Antitrypanosomal Agents

2010 · Dazhong Ding, Yaxue Zhao, et al. · ACS Medicinal Chemistry Letters · 105

Identification of a novel boron-containing antibacterial agent (AN0128) with anti-inflammatory activity, for the potential treatment of cutaneous diseases

2006 · Stephen J. Baker, Tsutomu Akama, et al. · Bioorganic & Medicinal Chemistry Letters · 94

Benzoxaboroles: A New Class of Potential Drugs for Human African Trypanosomiasis

2011 · Robert T Jacobs, Jacob J Plattner, et al. · Future Medicinal Chemistry · 93

Synthesis and structure–activity relationships of novel benzoxaboroles as a new class of antimalarial agents

2010 · Yong-Kang Zhang, Jacob J. Plattner, et al. · Bioorganic & Medicinal Chemistry Letters · 85

Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate

2017 · Yong-Kang Zhang, Jacob J. Plattner, et al. · Journal of Medicinal Chemistry · 66

Dynamic Receptor-dependent Activation of Inducible Nitric-oxide Synthase by ERK-mediated Phosphorylation of Ser745

2007 · Yongkang Zhang, Viktor Brovkovych, et al. · Journal of Biological Chemistry · 62

Benzoxaborole antimalarial agents. Part 2: Discovery of fluoro-substituted 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles

2011 · Yong-Kang Zhang, Jacob J. Plattner, et al. · Bioorganic & Medicinal Chemistry Letters · 56

Reactive Oxygen Species Scavenging Functional Hydrogel Delivers Procyanidins for the Treatment of Traumatic Brain Injury in Mice

2022 · Xuyang Huang, Yongqing Ye, et al. · ACS Applied Materials & Interfaces · 52

Synthesis and biological evaluations of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease

2010 · Charles Z. Ding, Yong-Kang Zhang, et al. · Bioorganic & Medicinal Chemistry Letters · 46

Synthesis and evaluation of novel α-amino cyclic boronates as inhibitors of HCV NS3 protease

2010 · Xianfeng Li, Yong-Kang Zhang, et al. · Bioorganic & Medicinal Chemistry Letters · 46

Identification of a 4-fluorobenzyl l-valinate amide benzoxaborole (AN11736) as a potential development candidate for the treatment of Animal African Trypanosomiasis (AAT)

2017 · Tsutomu Akama, Yong-Kang Zhang, et al. · Bioorganic & Medicinal Chemistry Letters · 45

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Synthesis and SAR of acyclic HCV NS3 protease inhibitors with novel P4-benzoxaborole moieties

2011 · Xianfeng Li, Suoming Zhang, et al. · Bioorganic & Medicinal Chemistry Letters · 45

Discovery of Novel Urea-Based Hepatitis C Protease Inhibitors with High Potency against Protease-Inhibitor-Resistant Mutants

2012 · Wieslaw M. Kazmierski, Robert Hamatake, et al. · Journal of Medicinal Chemistry · 41

Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles

2018 · Ning Zhang, Martin Zoltner, et al. · PLoS Pathogens · 40

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Benzoxaborole Antimalarial Agents. Part 4. Discovery of Potent 6-(2-(Alkoxycarbonyl)pyrazinyl-5-oxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles

2015 · Yong-Kang Zhang, Jacob J. Plattner, et al. · Journal of Medicinal Chemistry · 38

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Novel macrocyclic HCV NS3 protease inhibitors derived from α-amino cyclic boronates

2010 · Xianfeng Li, Yong-Kang Zhang, et al. · Bioorganic & Medicinal Chemistry Letters · 36

Plasmodium falciparum Resistance to a Lead Benzoxaborole Due to Blocked Compound Activation and Altered Ubiquitination or Sumoylation

2020 · Kirthana M. V. Sindhe, Wesley Wu, et al. · mBio · 34

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Discovery of an orally bioavailable isoxazoline benzoxaborole (AN8030) as a long acting animal ectoparasiticide

2015 · Yong-Kang Zhang, Jacob J. Plattner, et al. · Bioorganic & Medicinal Chemistry Letters · 33

An efficient synthesis for a new class antimalarial agent, 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole

2011 · Yong-Kang Zhang, Jacob J. Plattner, et al. · Tetrahedron Letters · 33

Synthesis of new acylsulfamoyl benzoxaboroles as potent inhibitors of HCV NS3 protease

2010 · Xianfeng Li, Yong-Kang Zhang, et al. · Bioorganic & Medicinal Chemistry Letters · 32

Works count: 53

Citation count: 2,914

H-index: 26

I10-index: 35