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Xuewu Zhang

Structural basis of STING binding with and phosphorylation by TBK1
2019 · Conggang Zhang, Guijun Shang, et al. · Nature · 1,074
Structures and Mechanisms in the cGAS-STING Innate Immunity Pathway
2020 · Xuewu Zhang, Xiao-chen Bai, et al. · Immunity · 830
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Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP
2019 · Guijun Shang, Conggang Zhang, et al. · Nature · 758
Mechanism for Activation of the EGF Receptor Catalytic Domain by the Juxtamembrane Segment
2009 · Natalia Jura, Nicholas F. Endres, et al. · Cell · 606
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Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 · Yibing Shan, Michael P. Eastwood, et al. · Cell · 357
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Catalytic Control in the EGF Receptor and Its Connection to General Kinase Regulatory Mechanisms
2011 · Natalia Jura, Xuewu Zhang, et al. · Molecular Cell · 309
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Activation of STING by targeting a pocket in the transmembrane domain
2022 · Defen Lu, Guijun Shang, et al. · Nature · 188
Structural basis for the prion-like MAVS filaments in antiviral innate immunity
2014 · Hui Xu, Xiaojing He, et al. · eLife · 183
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Plexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced Dimerization
2012 · Yuxiao Wang, Huawei He, et al. · Science Signaling · 162
Structural basis of the activation of c-MET receptor
2021 · Emiko Uchikawa, Zhiming Chen, et al. · Nature Communications · 143
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Sorting nexin 5 mediates virus-induced autophagy and immunity
2020 · Xiaonan Dong, Yuting Yang, et al. · Nature · 99
Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration
2009 · Huawei He, Taehong Yang, et al. · Proceedings of the National Academy of Sciences · 85
SNARE assembly enlightened by cryo-EM structures of a synaptobrevin–Munc18-1–syntaxin-1 complex
2022 · Karolina P. Stepien, Junjie Xu, et al. · Science Advances · 83
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Structural mechanisms of plexin signaling
2015 · Heath G. Pascoe, Yuxiao Wang, et al. · Progress in Biophysics and Molecular Biology · 78
Activation of human STING by a molecular glue-like compound
2023 · Jie Li, Stephen M. Canham, et al. · Nature Chemical Biology · 76
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Structural Analysis and Functional Implications of the Negative mTORC1 Regulator REDD1,
2010 · Silvia Vega-Rubin-de-Celis, Zeina Abdallah, et al. · Biochemistry · 76
Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin
2013 · Yuxiao Wang, Heath G Pascoe, et al. · eLife · 75
Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells
2015 · Ozlem Kulak, Hua Chen, et al. · Molecular and Cellular Biology · 70
Cryo-EM structure of the Hippo signaling integrator human STRIPAK
2021 · Byung-Cheon Jeong, Sung Jun Bae, et al. · Nature Structural & Molecular Biology · 66
Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands
2019 · Jie Li, Guijun Shang, et al. · eLife · 66
Synergistic activation of the insulin receptor via two distinct sites
2022 · Jie Li, Junhee Park, et al. · Nature Structural & Molecular Biology · 65
Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease
2013 · Michael T. Falta, Clemencia Pinilla, et al. · The Journal of Experimental Medicine · 61
Architecture of the Sema3A/PlexinA4/Neuropilin tripartite complex
2021 · Defen Lu, Guijun Shang, et al. · Nature Communications · 56
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Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complex
2017 · Guijun Shang, Chad A Brautigam, et al. · eLife · 56
Exploring a glycolytic inhibitor for the treatment of an FH-deficient type-2 papillary RCC
2011 · Toshinari Yamasaki, Tram Anh T. Tran, et al. · Nature Reviews Urology · 52
Works count: 110
Citation count: 6,265
H-index: 29
I10-index: 50
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