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Lu Tan

Computational Prediction of Metabolism: Sites, Products, SAR, P450 Enzyme Dynamics, and Mechanisms
2012 · Johannes Kirchmair, Mark J. Williamson, et al. · Journal of Chemical Information and Modeling · 289
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Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1-antitrypsin deficiency
2012 · Adriana Ordóñez, Erik L. Snapp, et al. · Hepatology · 137
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Circulating polymers in α 1 -antitrypsin deficiency
2014 · Lu Tan, Jennifer A. Dickens, et al. · European Respiratory Journal · 85
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hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiency
2018 · Charis-Patricia Segeritz, Sheikh Tamir Rashid, et al. · Journal of Hepatology · 68
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Integrating Structure‐ and Ligand‐Based Virtual Screening: Comparison of Individual, Parallel, and Fused Molecular Docking and Similarity Search Calculations on Multiple Targets
2008 · Lu Tan, Hanna Geppert, et al. · ChemMedChem · 68
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A single‐chain variable fragment intrabody prevents intracellular polymerization of Z α 1 ‐antitrypsin while allowing its antiproteinase activity
2015 · Adriana Ordóñez, Juan Pérez, et al. · The FASEB Journal · 49
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Aptamer Displacement Identifies Alternative Small-Molecule Target Sites that Escape Viral Resistance
2007 · Satoko Yamazaki, Lu Tan, et al. · Chemistry & Biology · 48
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Similarity Searching Using Fingerprints of Molecular Fragments Involved in Protein−Ligand Interactions
2008 · Lu Tan, Eugen Lounkine, et al. · Journal of Chemical Information and Modeling · 39
Software for Metabolism Prediction
2014 · Lu Tan, Johannes Kirchmair · Methods and principles in medicinal chemistry · 33
Effect of Nocturnal Oxygen Therapy on Nocturnal Hypoxemia and Sleep Apnea Among Patients With Chronic Obstructive Pulmonary Disease Traveling to 2048 Meters
2020 · Lu Tan, Tsogyal D. Latshang, et al. · JAMA Network Open · 31
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Tackling assay interference associated with small molecules
2024 · Lu Tan, Steffen Hirte, et al. · Nature Reviews Chemistry · 30
Anti-cancer Drug Development: Computational Strategies to Identify and Target Proteins Involved in Cancer Metabolism
2012 · Lora Mak, Sonia Liggi, et al. · Current Pharmaceutical Design · 30
Characterising the association of latency with α1-antitrypsin polymerisation using a novel monoclonal antibody
2014 · Lu Tan, Juan Perez, et al. · The International Journal of Biochemistry & Cell Biology · 28
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Computational Methodologies for Compound Database Searching that Utilize Experimental Protein–Ligand Interaction Information
2010 · Lu Tan, Jose Batista, et al. · Chemical Biology & Drug Design · 28
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Atom-Centered Interacting Fragments and Similarity Search Applications
2009 · José Batista, Lu Tan, et al. · Journal of Chemical Information and Modeling · 18
Utilizing Target–Ligand Interaction Information in Fingerprint Searching for Ligands of Related Targets
2009 · Lu Tan, Jürgen Bajorath · Chemical Biology & Drug Design · 18
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Three‐Dimensional Protein–Ligand Interaction Scaling of Two‐Dimensional Fingerprints
2009 · Lu Tan, Martin Vogt, et al. · Chemical Biology & Drug Design · 15
Rationalization of the Performance and Target Dependence of Similarity Searching Incorporating Protein−Ligand Interaction Information
2010 · Lu Tan, José Batista, et al. · Journal of Chemical Information and Modeling · 5
Support Vector Machine (SVM) Models for Predicting Inhibitors of the 3′ Processing Step of HIV‐1 Integrase
2013 · Shouyi Xuan, Maolin Wang, et al. · Molecular Informatics · 4
Anti-cancer Drug Development: Computational Strategies to Identify and Target Proteins Involved in Cancer Metabolism
2012 · Lora Mak, Sonia Liggi, et al. · Current Pharmaceutical Design · 3
429 National Evaluation of Confidence and Preparedness for Surgical Rotations in Medical Students and Foundation Year Doctors
2021 · L Tan, W Mullins, et al. · British journal of surgery · 1
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Anti-cancer Drug Development: Computational Strategies to Identify and Target Proteins Involved in Cancer Metabolism
2012 · Lora Mak, Sonia Liggi, et al. · Current Pharmaceutical Design · 1
Circulating Polymers Of Alpha-1 Antitrypsin In PI ZZ Subjects
2012 · Dawn L. DeMeo, Maria Elena Banos, et al. · 1
ChemInform Abstract: Similarity Searching Using Fingerprints of Molecular Fragments Involved in Protein—Ligand Interactions.
2009 · Lu Tan, Eugen Lounkine, et al. · ChemInform · 1
S64 Circulating polymers are found in alpha-1-antitrypsin deficiency and are associated with lung disease
2013 · JA Dickens, L Tan, et al. · Thorax
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Works count: 25
Citation count: 1,035
H-index: 16
I10-index: 17
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