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Jyrki Taskinen

Kinetics of Human Soluble and Membrane-Bound Catechol O-Methyltransferase: A Revised Mechanism and Description of the Thermolabile Variant of the Enzyme
1995 · Timo Lotta, Jukka Vidgren, et al. · Biochemistry · 1,180
Prediction of physicochemical properties based on neural network modelling
2003 · Jyrki Taskinen, Jouko Yliruusi · Advanced Drug Delivery Reviews · 225
Aqueous Solubility Prediction of Drugs Based on Molecular Topology and Neural Network Modeling
1998 · Jarmo Huuskonen, Marja Salo, et al. · Journal of Chemical Information and Computer Sciences · 167
X-ray Crystal Structure of Human Dopamine Sulfotransferase, SULT1A3
1999 · Rana Dajani, Anne Cleasby, et al. · Journal of Biological Chemistry · 160
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Expression and Characterization of Recombinant Human UDP-glucuronosyltransferases (UGTs)
2003 · Mika Kurkela, J. Arturo Garcı́a-Horsman, et al. · Journal of Biological Chemistry · 156
Relationship between immobilised artificial membrane chromatographic retention and the brain penetration of structurally diverse drugs
1997 · Timo Salminen, Anu Pulli, et al. · Journal of Pharmaceutical and Biomedical Analysis · 128
Comparison of Electrospray, Atmospheric Pressure Chemical Ionization, and Atmospheric Pressure Photoionization in the Identification of Apomorphine, Dobutamine, and Entacapone Phase II Metabolites in Biological Samples
2002 · Helena Keski-Hynnilä, Mika Kurkela, et al. · Analytical Chemistry · 112
Kinetic Characterization of the 1a Subfamily of Recombinant Human Udp-glucuronosyltransferases
2005 · Leena Luukkanen, Jyrki Taskinen, et al. · Drug Metabolism and Disposition · 100
Molecular Mechanisms Controlling the Rate and Specificity of Catechol O-Methylation by Human Soluble Catechol O-Methyltransferase
2001 · Pia Lautala, Ismo Ulmanen, et al. · Molecular Pharmacology · 98
Neural Network Modeling for Estimation of the Aqueous Solubility of Structurally Related Drugs
1997 · Jarmo Huuskonen, Marja Salo, et al. · Journal of Pharmaceutical Sciences · 93
Conjugation of Catechols by Recombinant Human Sulfotransferases, Udp-glucuronosyltransferases, and Soluble Catechol O-methyltransferase: Structure-conjugation Relationships and Predictive Models
2003 · Jyrki Taskinen, Brian T. Ethell, et al. · Drug Metabolism and Disposition · 67
Characterization of Catechol Glucuronidation in Rat Liver
2002 · Laurence Antonio, Joël-Paul Grillasca, et al. · Drug Metabolism and Disposition · 50
Chemical Composition of Angelica Root Oil.
1975 · Jyrki Taskinen, Lalli Nykänen, et al. · Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · 43
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Glucuronidation of 1-hydroxypyrene by human liver microsomes and human UDP-glucuronosyltransferases UGT1A6, UGT1A7, and UGT1A9: development of a high-sensitivity glucuronidation assay for human tissue.
2001 · L Luukkanen, J Mikkola, et al. · PubMed · 42
Characterization of 1‐Hydroxypyrene as a Novel Marker Substrate of 3‐Methylcholanthrene‐Inducible Phenol UDP‐Glucuronosyltransferase(s)
1997 · Leena Luukkanen, Eivor Elovaara, et al. · Pharmacology & Toxicology · 38
Enzyme-Assisted Synthesis and Structural Characterization of Nitrocatechol Glucuronides
1998 · Leena Luukkanen, Ilkka Kilpeläinen, et al. · Bioconjugate Chemistry · 36
Simultaneous determination of carbidopa, levodopa and 3,4-dihydroxyphenyl-acetic acid using high-performance liquid chromatography with electrochemical detection
1982 · Erkki Nissinen, Jyrki Taskinen · Journal of Chromatography B Biomedical Sciences and Applications · 34
A model for human cardiac troponin C and for modulation of its Ca 2+ affinity by drugs
1991 · Martti Ovaska, Jyrki Taskinen · Proteins Structure Function and Bioinformatics · 33
Regioselective sulfonation of dopamine by SULT1A3 in vitro provides a molecular explanation for the preponderance of dopamine-3-O-sulfate in human blood circulation
2007 · Katriina Itäaho, Sami Alakurtti, et al. · Biochemical Pharmacology · 31
Microplate screening assay to identify inhibitors of human catechol-O-methyltransferase
2004 · Mika Kurkela, Antti Siiskonen, et al. · Analytical Biochemistry · 30
PLS modelling of structure?activity relationships of catechol O-methyltransferase inhibitors
1992 · Timo Lotta, Jyrki Taskinen, et al. · Journal of Computer-Aided Molecular Design · 29
Quantitation of entacapone glucuronide in rat plasma by on-line coupled restricted access media column and liquid chromatography–tandem mass spectrometry
2001 · Helena Keski-Hynnilä, Knut Raanaa, et al. · Journal of Chromatography B Biomedical Sciences and Applications · 28
Composition of the Essential Oil of Sweet Marjoram Obtained by Distillation with Steam and by Extraction and Distillation with Alcohol-Water Mixture.
1974 · Jyrki Taskinen, Staffan Josephson, et al. · Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · 28
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N-Glucuronidation of Some 4-Arylalkyl-1H-Imidazoles by Rat, Dog, and Human Liver Microsomes
2002 · Sanna Kaivosaari, Jarmo S. Salonen, et al. · Drug Metabolism and Disposition · 27
Direct analysis of nitrocatechol-type glucuronides in urine by capillary electrophoresis–electrospray ionisation mass spectrometry and tandem mass spectrometry
2000 · Helena Keski-Hynnilä, Knut Raanaa, et al. · Journal of Chromatography B Biomedical Sciences and Applications · 27
Works count: 68
Citation count: 3,376
H-index: 25
I10-index: 47
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