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Michael Rothe

Gene Therapy for Wiskott-Aldrich Syndrome—Long-Term Efficacy and Genotoxicity
2014 · Christian Jörg Braun, Kaan Boztug, et al. · Science Translational Medicine · 560
Tumour ischaemia by interferon-γ resembles physiological blood vessel regression
2017 · Thomas Kammertoens, Christian Friese, et al. · Nature · 269
Bromo- and Extraterminal Domain Chromatin Regulators Serve as Cofactors for Murine Leukemia Virus Integration
2013 · Saumya Shree Gupta, Tobias Maetzig, et al. · Journal of Virology · 139
Preclinical Evaluation of Efficacy and Safety of an Improved Lentiviral Vector for the Treatment of β-Thalassemia and Sickle Cell Disease
2014 · Olivier Negre, Cynthia Bartholomae, et al. · Current Gene Therapy · 125
Repopulation Efficiencies of Adult Hepatocytes, Fetal Liver Progenitor Cells, and Embryonic Stem Cell-Derived Hepatic Cells in Albumin-Promoter-Enhancer Urokinase-Type Plasminogen Activator Mice
2009 · Dhivya Haridass, Qinggong Yuan, et al. · American Journal Of Pathology · 113
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Biosafety Challenges for Use of Lentiviral Vectors in Gene Therapy
2014 · Michael Rothe, Ute Modlich, et al. · Current Gene Therapy · 109
Massive Clonal Selection and Transiently Contributing Clones During Expansion of Mesenchymal Stem Cell Cultures Revealed by Lentiviral RGB-Barcode Technology
2016 · Anton Selich, Jannik Daudert, et al. · Stem Cells Translational Medicine · 96
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DNA methylation changes during long-term in vitro cell culture are caused by epigenetic drift
2021 · Julia Franzen, Theodoros Georgomanolis, et al. · Communications Biology · 87
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Preclinical safety and efficacy of an anti–HIV-1 lentiviral vector containing a short hairpin RNA to CCR5 and the C46 fusion inhibitor
2014 · Orit Wolstein, Maureen Boyd, et al. · Molecular Therapy — Methods & Clinical Development · 73
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Preclinical Evaluation of a Novel Lentiviral Vector Driving Lineage-Specific BCL11A Knockdown for Sickle Cell Gene Therapy
2020 · Christian Brendel, Olivier Negre, et al. · Molecular Therapy — Methods & Clinical Development · 72
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Lentiviral Gene Therapy Using Cellular Promoters Cures Type 1 Gaucher Disease in Mice
2015 · Maria Dahl, Alexander Doyle, et al. · Molecular Therapy · 67
Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID
2020 · Laura Garcia-Perez, Marja van Eggermond, et al. · Molecular Therapy — Methods & Clinical Development · 56
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Lentivirus Mediated Correction of Artemis-Deficient Severe Combined Immunodeficiency
2016 · Divya Punwani, Misako Kawahara, et al. · Human Gene Therapy · 55
Predicting genotoxicity of viral vectors for stem cell gene therapy using gene expression-based machine learning
2021 · Adrian Schwarzer, Steven R. Talbot, et al. · Molecular Therapy · 50
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Preclinical Development of a Lentiviral Vector for Gene Therapy of X-Linked Severe Combined Immunodeficiency
2018 · Valentina Poletti, Sabine Charrier, et al. · Molecular Therapy — Methods & Clinical Development · 50
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Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34 + Cells for Correction of Fabry Disease
2017 · Ju Huang, Aneal Khan, et al. · Molecular Therapy — Methods & Clinical Development · 49
Umbilical cord as a long-term source of activatable mesenchymal stromal cells for immunomodulation
2019 · Anton Selich, Katharina Zimmermann, et al. · Stem Cell Research & Therapy · 46
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Analyzing the Genotoxicity of Retroviral Vectors in Hematopoietic Cell Gene Therapy
2017 · Luca Biasco, Michael Rothe, et al. · Molecular Therapy — Methods & Clinical Development · 44
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Non-Clinical Efficacy and Safety Studies on G1XCGD, a Lentiviral Vector for Ex Vivo Gene Therapy of X-Linked Chronic Granulomatous Disease
2018 · Christian Brendel, Michael Rothe, et al. · Human Gene Therapy Clinical Development · 36
Gene therapy cures the anemia and lethal bone marrow failure in a mouse model of RPS19-deficient Diamond-Blackfan anemia
2014 · P. Jaako, S. Debnath, et al. · Haematologica · 36
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Induction of a mature hepatocyte phenotype in adult liver derived progenitor cells by ectopic expression of transcription factors
2011 · Razvan Iacob, Urda Rüdrich, et al. · Stem Cell Research · 33
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Safety of Gene Therapy: New Insights to a Puzzling Case
2014 · Michael Rothe, Axel Schambach, et al. · Current Gene Therapy · 32
Haematopoietic gene therapy of non-conditioned patients with Fanconi anaemia-A: results from open-label phase 1/2 (FANCOLEN-1) and long-term clinical trials
2024 · Paula Río, Josune Zubicaray, et al. · The Lancet · 31
CRISPR/Cas9 Immunoengineering of Hoxb8-Immortalized Progenitor Cells for Revealing CCR7-Mediated Dendritic Cell Signaling and Migration Mechanisms in vivo
2018 · Swantje I. Hammerschmidt, Kathrin Werth, et al. · Frontiers in Immunology · 31
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Cell culture media notably influence properties of human mesenchymal stroma/stem-like cells from different tissues
2020 · Andreas Winkel, Yarúa Jaimes, et al. · Cytotherapy · 30
Works count: 111
Citation count: 2,894
H-index: 26
I10-index: 48
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