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Laurent B. Nicolas
Observed names:
L.B. Nicolas,
Laurent B Nicolas,
Laurent Nicolas,
Nicolas, Laurent B.
Institution:
CSL (Switzerland)
Observed institutions:
F. Hoffmann-La Roche AG,
Centre National de la Recherche Scientifique,
Boehringer Ingelheim (Germany),
University College London,
CSL (Switzerland),
Actelion (Switzerland)
show all 6
OpenAlex ID:
A5103501686
A combined marble burying–locomotor activity test in mice: A practical screening test with sensitivity to different classes of anxiolytics and antidepressants
2006
·
Laurent B. Nicolas
, Yeter Kolb
, et al.
·
European Journal of Pharmacology
·
238
Aggressive behavior induced by the steroid sulfatase inhibitor COUMATE and by DHEAS in CBA/H mice
2001
·
Laurent B Nicolas
, Walter Pinoteau
, et al.
·
Brain Research
·
65
Development and validation of a fully automated online human dried blood spot analysis of bosentan and its metabolites using the Sample Card And Prep DBS System
2011
·
Norbert Ganz
, Maharajah Singrasa
, et al.
·
Journal of Chromatography B
·
54
Loss of Aggression, After Transfer onto a C57BL/6J Background, in Mice Carrying a Targeted Disruption of the Neuronal Nitric Oxide Synthase Gene
2000
·
Isabelle Le Roy
, Stéphanie Pothion
, et al.
·
Behavior Genetics
·
46
Social approach–avoidance behavior of a high-anxiety strain of rats: effects of benzodiazepine receptor ligands
2005
·
Laurent B. Nicolas
, Eric P. M. Prinssen
·
Psychopharmacology
·
44
Defensive-like behaviors induced by ultrasound: further pharmacological characterization in Lister-hooded rats
2007
·
Laurent B. Nicolas
, Steffen Klein
, et al.
·
Psychopharmacology
·
24
Investigation of the predictive validity of laser‐EPs in normal, UVB‐inflamed and capsaicin‐irritated skin with four analgesic compounds in healthy volunteers
2017
·
Klaus Schaffler
, Laurent B. Nicolas
, et al.
·
British Journal of Clinical Pharmacology
·
23
Examining face and construct validity of a noninvasive model of panic disorder in Lister-hooded rats
2010
·
Steffen Klein
, Laurent B. Nicolas
, et al.
·
Psychopharmacology
·
17
Brain Pathways Mediating the Pro-Aggressive Effect of the Steroid Sulfatase (Sts) Gene
2010
·
Stephane Mortaud
, Laurent Nicolas
, et al.
·
Behavior Genetics
·
17
Integrated pharmacokinetics and pharmacodynamics of epoprostenol in healthy subjects
2012
·
Laurent B. Nicolas
, Andreas Krause
, et al.
·
British Journal of Clinical Pharmacology
·
16
PDF
Relative bioavailability of a newly developed pediatric formulation of bosentan vs. the adult formulation
2013
·
Marcelo M. Gutierrez
, Laurent B. Nicolas
, et al.
·
International Journal of Clinical Pharmacology and Therapeutics
·
14
Imaging trait anxiety in high anxiety F344 rats: Focus on the dorsomedial prefrontal cortex
2011
·
Eric P. Prinssen
, Laurent B. Nicolas
, et al.
·
European Neuropsychopharmacology
·
14
Determination of 6-keto prostaglandin F1α and its metabolites in human plasma by LC–MS/MS
2012
·
Mark Enzler
, Stefan Schipp
, et al.
·
Journal of Chromatography B
·
13
Comparative Pharmacokinetic, Pharmacodynamic, Safety, and Tolerability Profiles of 3 Different Formulations of Epoprostenol Sodium for Injection in Healthy Men
2013
·
Laurent B. Nicolas
, Marcelo M. Gutierrez
, et al.
·
Clinical Therapeutics
·
11
The steroid sulfatase inhibitor COUMATE attenuates rather than enhances access of dehydroepiandrosterone sulfate to the brain in the mouse
2007
·
Laurent B. Nicolas
, Jonathan P. Fry
·
Brain Research
·
10
P3‐283: Pharmacokinetics, pharmacodynamics, and safety of the novel bace inhibitor bi1181181 after oral administration of single ascending doses in healthy subjects
2015
·
Laurent Nicolas
, Klaus-Peter Kammerer
, et al.
·
Alzheimer s & Dementia
·
7
P3‐282: Single oral doses of the novel bace inhibitor bi 1181181 significantly reduce concentrations of cerebrospinal fluid amyloid‐beta peptides in healthy subjects
2015
·
Andreas Borta
, Laurent Nicolas
, et al.
·
Alzheimer s & Dementia
·
7
PDF
Clinical pharmacology of single‐ and multiple‐ascending doses of ACT ‐178882, a new direct renin inhibitor, and its pharmacokinetic interaction with food and midazolam
2012
·
Jasper Dingemanse
, Laurent Nicolas
, et al.
·
Fundamental and Clinical Pharmacology
·
7
Pharmacokinetics, Pharmacodynamics, and Tolerability of ACT-077825, a New Direct Renin Inhibitor After Multiple-ascending Doses in Healthy Subjects
2012
·
Laurent B. Nicolas
, Marcelo Gutierrez
, et al.
·
Journal of Cardiovascular Pharmacology
·
6
Investigation of combined CYP3A4 inductive/inhibitory properties by studying statin interactions: a model study with the renin inhibitor ACT-178882
2014
·
Jasper Dingemanse
, Laurent B. Nicolas
, et al.
·
European Journal of Clinical Pharmacology
·
5
Entry-into-humans study with a new direct renin inhibitor
2012
·
Laurent B. Nicolas
, Marcelo M. Gutierrez
, et al.
·
European Journal of Clinical Pharmacology
·
5
Effect of Multiple‐Dose Diltiazem on the Pharmacokinetics of the Renin Inhibitor ACT‐077825
2013
·
Jasper Dingemanse
, Laurent B. Nicolas
, et al.
·
Clinical Pharmacology in Drug Development
·
3
Drug-Drug Interaction Study of ACT-178882, a New Renin Inhibitor, and Diltiazem in Healthy Subjects
2013
·
Jasper Dingemanse
, Laurent Nicolas
·
Clinical Drug Investigation
·
3
Age and Sex Effects on the Single‐ and Multiple‐Dose Safety and Pharmacokinetics of the New Renin Inhibitor ACT ‐178882
2013
·
Jasper Dingemanse
, Laurent Nicolas
·
Cardiovascular Therapeutics
·
3
PDF
Safety and antimicrobial efficacy of CSL787, a novel nebulized IgG therapy, in patients with bronchiectasis: results from a randomized phase 1 trial
2026
·
Damian G Downey
, Ilka Schulze
, et al.
·
American Journal of Respiratory and Critical Care Medicine
·
1
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Works count:
34
Citation count:
654
H-index:
13
I10-index:
15
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