Author

Yuan Lian

Institutions: Broad Institute, Harvard University, University of Massachusetts Chan Medical School, Ionis Pharmaceuticals (United States)

Observed institutions: Broad Institute, Harvard University, University of Massachusetts Chan Medical School, Ionis Pharmaceuticals (United States), Stanley Center for Psychiatric Research

ORCID: 0009-0001-9565-2292

Observed ORCID: 0009-0001-9565-2292

OpenAlex ID: A5108904673

In vivo base editing extends lifespan of a humanized mouse model of prion disease

2025 · Meirui An, Jessie R. Davis, et al. · Nature Medicine · 49

Divalent siRNA for prion disease

2026 · Juliana E Gentile, Taylor L Corridon, et al. · Nucleic Acids Research · 27

Zinc Finger Repressors mediate widespread PRNP lowering in the nonhuman primate brain and profoundly extend survival in prion disease mice

2025 · Shih-Wei Chou, Meredith A Mortberg, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 13

PrP turnover in vivo and the time to effect of prion disease therapeutics

2026 · Taylor L Corridon, Jill O’Moore, et al. · PLoS Pathogens · 7

Search for a genetic cause of variably protease-sensitive prionopathy

2025 · Yuan Lian, Keisi Kotobelli, et al. · PLoS Pathogens · 3

Mortality of individuals with antemortem genetic testing for PRNP variants in the United States, 1998-2024

2025 · Yuan Lian, Keisi Kotobelli, et al. · medRxiv · 2

Cell Type Distribution of Intrathecal Antisense Oligonucleotide Activity in Deep Brain Regions of Non-Human Primates

2025 · Jeannine A Frei, Juliana E Gentile, et al. · Nucleic Acid Therapeutics · 2

Author Correction: In vivo base editing extends lifespan of a humanized mouse model of prion disease

2025 · Meirui An, Jessie R. Davis, et al. · Nature Medicine · 1

Mortality of Individuals With PRNP Variants Associated With Prion Disease in the United States, 1998–2024

2026 · Yuan Lian, Keisi Kotobelli, et al. · Neurology Genetics

Works count: 9

Citation count: 104

H-index: 4

I10-index: 3