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Tadayuki Takashima

PET Imaging–Based Evaluation of Hepatobiliary Transport in Humans with (15R)-11C-TIC-Me
2012 · Tadayuki Takashima, Satoshi Kitamura, et al. · Journal of Nuclear Medicine · 103
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mRNA Expression and Transport Characterization of Conditionally Immortalized Rat Brain Capillary Endothelial Cell Lines; a Newin vitroBBB Model for Drug Targeting
2000 · Ken-Ichi Hosoya, Tadayuki Takashima, et al. · Journal of drug targeting · 101
In Vivo Expression of Cyclooxygenase-1 in Activated Microglia and Macrophages During Neuroinflammation Visualized by PET with 11C-Ketoprofen Methyl Ester
2011 · Miho Shukuri, Misato Takashima-Hirano, et al. · Journal of Nuclear Medicine · 93
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Characterization of the Amino Acid Transport of New Immortalized Choroid Plexus Epithelial Cell Lines: A Novel In Vitro System for Investigating Transport Functions at the Blood-Cerebrospinal Fluid Barrier
2001 · Takeo Kitazawa, Ken-ichi Hosoya, et al. · Pharmaceutical Research · 68
General Method for the 11C‐Labeling of 2‐Arylpropionic Acids and Their Esters: Construction of a PET Tracer Library for a Study of Biological Events Involved in COXs Expression
2010 · Misato Takashima‐Hirano, Miho Shukuri, et al. · Chemistry - A European Journal · 60
The Involvement of Organic Anion Transporting Polypeptide in the Hepatic Uptake of Telmisartan in Rats: PET Studies with [11C]Telmisartan
2011 · Tadayuki Takashima, Yoshinobu Hashizume, et al. · Molecular Pharmaceutics · 57
PET Imaging of the Gastrointestinal Absorption of Orally Administered Drugs in Conscious and Anesthetized Rats
2011 · Shinji Yamashita, Tadayuki Takashima, et al. · Journal of Nuclear Medicine · 56
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Developmental Changes in P-Glycoprotein Function in the Blood–Brain Barrier of Nonhuman Primates: PET Study withR-11C-Verapamil and11C-Oseltamivir
2011 · Tadayuki Takashima, Chihiro Yokoyama, et al. · Journal of Nuclear Medicine · 55
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11C-PK11195 PET for the In Vivo Evaluation of Neuroinflammation in the Rat Brain After Cortical Spreading Depression
2009 · Yilong Cui, Tadayuki Takashima, et al. · Journal of Nuclear Medicine · 55
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Evaluation of Oatp and Mrp2 Activities in Hepatobiliary Excretion Using Newly Developed Positron Emission Tomography Tracer [11C]Dehydropravastatin in Rats
2013 · Tomotaka Shingaki, Tadayuki Takashima, et al. · Journal of Pharmacology and Experimental Therapeutics · 54
Whole-body distribution and radiation dosimetry of [11C]telmisartan as a biomarker for hepatic organic anion transporting polypeptide (OATP) 1B3
2012 · Keiji Shimizu, Tadayuki Takashima, et al. · Nuclear Medicine and Biology · 51
Positron Emission Tomography Studies Using (15R)-16-m-[11C]tolyl-17,18,19,20-tetranorisocarbacyclin Methyl Ester for the Evaluation of Hepatobiliary Transport
2010 · Tadayuki Takashima, Hiroko Nagata, et al. · Journal of Pharmacology and Experimental Therapeutics · 51
Investigation of the effect of active efflux at the blood–brain barrier on the distribution of nonsteroidal aromatase inhibitors in the central nervous system
2013 · Mari Miyajima, Hiroyuki Kusuhara, et al. · Journal of Pharmaceutical Sciences · 47
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Quantitative Evaluation of mMate1 Function Based on Minimally Invasive Measurement of Tissue Concentration Using PET with [11C]Metformin in Mouse
2015 · Tomotaka Shingaki, W. Ewan Hume, et al. · Pharmaceutical Research · 41
Human whole-body biodistribution and dosimetry of a new PET tracer, [11C]ketoprofen methyl ester, for imagings of neuroinflammation
2014 · Akihito Ohnishi, Michio Senda, et al. · Nuclear Medicine and Biology · 40
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The synthesis and biodistribution of [11C]metformin as a PET probe to study hepatobiliary transport mediated by the multi-drug and toxin extrusion transporter 1 (MATE1) in vivo
2013 · W. Ewan Hume, Tomotaka Shingaki, et al. · Bioorganic & Medicinal Chemistry · 40
Effect of Cyclosporin A and Impact of Dose Staggering on OATP1B1/1B3 Endogenous Substrates and Drug Probes for Assessing Clinical Drug Interactions
2022 · Tatsuki Mochizuki, Maciej J. Zamek‐Gliszczynski, et al. · Clinical Pharmacology & Therapeutics · 38
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11 C-Cetrozole: An Improved C- 11 C-Methylated PET Probe for Aromatase Imaging in the Brain
2014 · Kayo Takahashi, Takamitsu Hosoya, et al. · Journal of Nuclear Medicine · 38
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Evaluation of Breast Cancer Resistance Protein Function in Hepatobiliary and Renal Excretion Using PET with11C-SC-62807
2013 · Tadayuki Takashima, Chunyong Wu, et al. · Journal of Nuclear Medicine · 38
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Efficient sequential synthesis of PET Probes of the COX-2 inhibitor [11C]celecoxib and its major metabolite [11C]SC-62807 and in vivo PET evaluation
2011 · Misato Takashima-Hirano, Tadayuki Takashima, et al. · Bioorganic & Medicinal Chemistry · 36
Physiologically‐based pharmacokinetic model‐based translation of OATP1B ‐mediated drug–drug interactions from coproporphyrin I to probe drugs
2022 · Tatsuki Mochizuki, Yasunori Aoki, et al. · Clinical and Translational Science · 34
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Association between aromatase in human brains and personality traits
2018 · Kayo Takahashi, Takamitsu Hosoya, et al. · Scientific Reports · 33
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Dynamic Analysis of Fluid Distribution in the Gastrointestinal Tract in Rats: Positron Emission Tomography Imaging after Oral Administration of Nonabsorbable Marker, [18F]Deoxyfluoropoly(ethylene glycol)
2013 · Tadayuki Takashima, Tomotaka Shingaki, et al. · Molecular Pharmaceutics · 33
Evaluation of Dextromethorphan Metabolism Using Hepatocytes from CYP2D6 Poor and Extensive Metabolizers
2005 · Tadayuki Takashima, Shigeo Murase, et al. · Drug Metabolism and Pharmacokinetics · 32
Use of [18F]FDOPA-PET for in vivo evaluation of dopaminergic dysfunction in unilaterally 6-OHDA-lesioned rats
2011 · Kiyoshi Kyono, Tadayuki Takashima, et al. · EJNMMI Research · 31
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Works count: 42
Citation count: 1,432
H-index: 26
I10-index: 33
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