Author

Bruce A. Posner

Observed names: B. A. POSNER, B. A. Posner, B. Posner, B.A. Posner, BA Posner, Bruce A Posner, Bruce Posner, Posner, Bruce A.

Institution: The University of Texas Southwestern Medical Center

Observed institutions: Pennsylvania State University, Howard Hughes Medical Institute, Pfizer (United States), Baylor College of Medicine, University of Chicago, Harold C. Simmons Comprehensive Cancer Center, Rockefeller University, The University of Texas Southwestern Medical Center

ORCID: 0000-0002-7033-4933

Observed ORCID: 0000-0002-7033-4933

OpenAlex ID: A5109282945

The structure of the G protein heterotrimer Giα1β1γ2

1995 · Mark A. Wall, David E. Coleman, et al. · Cell · 1,123

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Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells

2016 · Michael Ramirez, Satwik Rajaram, et al. · Nature Communications · 575

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Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan

2017 · Chensu Wang, Hanspeter Niederstrasser, et al. · Nature Communications · 156

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Regulators of G Protein Signaling 6 and 7

1999 · Bruce A. Posner, Alfred G. Gilman, et al. · Journal of Biological Chemistry · 134

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Structural basis of activity and subunit recognition in G protein heterotrimers

1998 · Mark A Wall, Bruce A Posner, et al. · Structure · 97

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Deciphering the impact of genomic variation on function

2024 · Writing group (ordered by contribution), Jesse M. Engreitz, et al. · Nature · 90

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The A326S Mutant of Giα1 as an Approximation of the Receptor-bound State

1998 · Bruce A. Posner, Mark B. Mixon, et al. · Journal of Biological Chemistry · 85

Modulation of the Affinity and Selectivity of RGS Protein Interaction with Gα Subunits by a Conserved Asparagine/Serine Residue

1999 · Bruce A. Posner, Suchetana Mukhopadhyay, et al. · Biochemistry · 79

Towards patient-based cancer therapeutics

2010 · The Cancer Target Discovery and Development Network, Stuart L Schreiber, et al. · Nature Biotechnology · 66

Visualizing Signal Transduction: Receptors, G-Proteins, and Adenylate Cyclases

1996 · Carmen W. Dessauer, Bruce A. Posner, et al. · Clinical Science · 57

Engineering Specificity for Folate into Dihydrofolate Reductase from Escherichia coli

1996 · Bruce A. Posner, Luyuan Li, et al. · Biochemistry · 33

Identification of spirocyclic piperidine-azetidine inverse agonists of the ghrelin receptor

2012 · Daniel W. Kung, Steven B. Coffey, et al. · Bioorganic & Medicinal Chemistry Letters · 27

Discovery of Cytochrome P450 4F11 Activated Inhibitors of Stearoyl Coenzyme A Desaturase

2018 · Sarah E. Winterton, Emanuela Capota, et al. · Journal of Medicinal Chemistry · 26

Synthesis and Biological Evaluation of Kibdelone C and Its Simplified Derivatives

2016 · Janjira Rujirawanich, Soyeon Kim, et al. · Journal of the American Chemical Society · 22

Chemical intervention of influenza virus mRNA nuclear export

2020 · Matthew Esparza, Amir Mor, et al. · PLoS Pathogens · 20

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Stereospecific deoxygenation of 1,2-diols to olefins

1987 · John L. King, Bruce A. Posner, et al. · Tetrahedron Letters · 16

A highly-sensitive high throughput assay for dynamin's basal GTPase activity

2017 · Aparna Mohanakrishnan, Triet Vincent M. Tran, et al. · PLoS ONE · 11

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Structural Insights into Novel 15-Prostaglandin Dehydrogenase Inhibitors

2021 · Prema L. Mallipeddi, Yongyou Zhang, et al. · Molecules · 10

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Simultaneous Control of Endogenous and User-Defined Genetic Pathways Using Unique ecDHFR Pharmacological Chaperones

2020 · Prerana Ramadurgum, DaNae R. Woodard, et al. · Cell chemical biology · 10

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A Multipronged Approach Establishes Covalent Modification of β-Tubulin as the Mode of Action of Benzamide Anti-cancer Toxins

2020 · Juan Manuel Povedano, Rameshu Rallabandi, et al. · Journal of Medicinal Chemistry · 9

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Abstract 5757: A new functional classification of lung and breast cancers based on siRNA mediated knockdown of 48 NRs and 72 CoRegulators

2012 · Ryan Carstens, Kenneth Huffman, et al. · Cancer Research · 6

Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers

2023 · Kenneth E. Huffman, Long Shan Li, et al. · Frontiers in Oncology · 4

Author Correction: Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan

2018 · Chensu Wang, Hanspeter Niederstrasser, et al. · Nature Communications · 4

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The crystallographic structure of a G protein heterotrimer

1996 · S. R. Sprang, M. A. Wall, et al. · Acta Crystallographica Section A Foundations of Crystallography · 2

CDK8 Inhibition Induces Mediator Trapping and Impairment of the EWSR1::FLI1 Transcriptional Program in Ewing Sarcoma

2026 · James H. McGinnis, Shuai Wang, et al. · Cancer Discovery · 1

Works count: 40

Citation count: 2,664

H-index: 16

I10-index: 19