Author

Thea Mulder‐Krieger

Observed name: Thea Mulder-Krieger

OpenAlex ID: A5110009618

Functional efficacy of adenosine A 2A receptor agonists is positively correlated to their receptor residence time

2012 · Dong Guo, Thea Mulder‐Krieger, et al. · British Journal of Pharmacology · 184

New, Non-Adenosine, High-Potency Agonists for the Human Adenosine A2B Receptor with an Improved Selectivity Profile Compared to the Reference Agonist N-Ethylcarboxamidoadenosine

2004 · Margot W. Beukers, Lisa C. W. Chang, et al. · Journal of Medicinal Chemistry · 154

2-Amino-6-furan-2-yl-4-substituted Nicotinonitriles as A2A Adenosine Receptor Antagonists

2008 · Monica Mantri, Olivier de Graaf, et al. · Journal of Medicinal Chemistry · 151

Predicting Binding Affinities for GPCR Ligands Using Free-Energy Perturbation

2016 · Eelke B. Lenselink, Julien Louvel, et al. · ACS Omega · 147

A Series of Ligands Displaying a Remarkable Agonistic−Antagonistic Profile at the Adenosine A1 Receptor

2004 · Lisa C. W. Chang, Jacobien K. von Frijtag Drabbe Künzel, et al. · Journal of Medicinal Chemistry · 113

2,4,6-Trisubstituted Pyrimidines as a New Class of Selective Adenosine A 1 Receptor Antagonists

2004 · Lisa C. W. Chang, Ronald F. Spanjersberg, et al. · Journal of Medicinal Chemistry · 102

Dual-Point Competition Association Assay: A Fast and High-Throughput Kinetic Screening Method for Assessing Ligand-Receptor Binding Kinetics

2012 · Dong Guo, Erika J.H. van Dorp, et al. · SLAS DISCOVERY · 67

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A Series of 2,4-Disubstituted Quinolines as a New Class of Allosteric Enhancers of the Adenosine A3Receptor

2009 · Laura H. Heitman, Anikó Göblyös, et al. · Journal of Medicinal Chemistry · 64

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Identifying Novel Adenosine Receptor Ligands by Simultaneous Proteochemometric Modeling of Rat and Human Bioactivity Data

2012 · Gerard J. P. van Westen, Olaf O. van den Hoven, et al. · Journal of Medicinal Chemistry · 54

The endocannabinoid 2-arachidonylglycerol is a negative allosteric modulator of the human A3 adenosine receptor

2009 · J. Robert Lane, Margot W. Beukers, et al. · Biochemical Pharmacology · 52

A new generation of adenosine receptor antagonists: From di- to trisubstituted aminopyrimidines

2008 · Jacobus P.D. van Veldhoven, Lisa C.W. Chang, et al. · Bioorganic & Medicinal Chemistry · 45

2,6-Disubstituted and 2,6,8-Trisubstituted Purines as Adenosine Receptor Antagonists

2006 · Lisa C. W. Chang, Ronald F. Spanjersberg, et al. · Journal of Medicinal Chemistry · 45

Molecular mechanism of positive allosteric modulation of the metabotropic glutamate receptor 2 by JNJ‐46281222

2015 · Maarten L J Doornbos, Laura Pérez‐Benito, et al. · British Journal of Pharmacology · 43

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Discovery and Kinetic Profiling of 7-Aryl-1,2,4-triazolo[4,3- a ]pyridines: Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 2

2017 · Maarten L. J. Doornbos, José María Cid, et al. · Journal of Medicinal Chemistry · 41

2,6,8-Trisubstituted 1-Deazapurines as Adenosine Receptor Antagonists

2007 · Lisa C. W. Chang, Jacobien K. von Frijtag Drabbe Künzel, et al. · Journal of Medicinal Chemistry · 39

Synthesis and biological evaluation of 2-aminothiazoles and their amide derivatives on human adenosine receptors. Lack of effect of 2-aminothiazoles as allosteric enhancers

2005 · Anikó Göblyös, Sabrina Neves Santiago, et al. · Bioorganic & Medicinal Chemistry · 38

Multi-Objective Evolutionary Design of Adenosine Receptor Ligands

2012 · Eelke van der Horst, Patricia Marqués-Gallego, et al. · Journal of Chemical Information and Modeling · 36

Structure-kinetics relationships of Capadenoson derivatives as adenosine A 1 receptor agonists

2015 · Julien Louvel, Dong Guo, et al. · European Journal of Medicinal Chemistry · 34

Allosteric modulation, thermodynamics and binding to wild‐type and mutant (T277A) adenosine A1receptors of LUF5831, a novel nonadenosine‐like agonist

2006 · Laura H Heitman, Thea Mulder‐Krieger, et al. · British Journal of Pharmacology · 28

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Substructure‐Based Virtual Screening for Adenosine A 2A Receptor Ligands

2011 · Eelke van der Horst, Rianne van der Pijl, et al. · ChemMedChem · 26

A New Class of Fluorinated A2A Adenosine Receptor Agonist with Application to Last‐Step Enzymatic [18F]Fluorination for PET Imaging

2017 · Phillip T. Lowe, Sergio Dall'Angelo, et al. · ChemBioChem · 19

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Putative role of the adenosine A3 receptor in the antiproliferative action of N 6-(2-isopentenyl)adenosine

2011 · Clara C. Blad, Jacobien K. von Frijtag Drabbe Künzel, et al. · Purinergic Signalling · 19

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Synthesis and evaluation of N-substituted 2-amino-4,5-diarylpyrimidines as selective adenosine A1 receptor antagonists

2016 · Georgios Alachouzos, Eelke B. Lenselink, et al. · European Journal of Medicinal Chemistry · 14

HPLC Analysis of Alkaloids in Extracts of Callus Cultures of Cinchona Species

1984 · Robert Verpoorte, Thea Mulder-Krieger, et al. · Zeitschrift für Naturforschung C · 11

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Phenotypic screening of cannabinoid receptor 2 ligands shows different sensitivity to genotype

2017 · Julia M. Hillger, Beau le Roy, et al. · Biochemical Pharmacology · 9

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Works count: 26

Citation count: 1,535

H-index: 20

I10-index: 24