Author

Barbara C.F. Chu

Observed names: B B Chu, B C Chu, B.C.F. CHU, B.C.F. Chu, BARBARA C.F. CHU, Barbara C. E Chu, Barbara C. F. Chu

Observed institutions: Salk Institute for Biological Studies, Memorial Sloan Kettering Cancer Center, Institute of Cancer Research, University of Cambridge, Columbia University Irving Medical Center, University of California System, University of California San Diego, Cambridge Science Centre, Scripps Clinic, Columbia University

OpenAlex ID: A5110015501

Derivatization of unprotected polynucleotides

1983 · Barbara C.F. Chu, Geoffrey M. Wahl, et al. · Nucleic Acids Research · 182

Nonenzymatic sequence-specific cleavage of single-stranded DNA.

1985 · B C Chu, L E Orgel · Proceedings of the National Academy of Sciences · 150

The stability of different forms of double-stranded decoy DNA in serum and nuclear extracts

1992 · Barbara C.F. Chu, Leslie E. Orgel · Nucleic Acids Research · 81

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Methotrexate pharmacokinetics after intraarticular injection in patients with rheumatoid arthritis

1980 · Scott M. Wigginton, Barbara C. F. Chu, et al. · Arthritis & Rheumatism · 77

Long-duration intracavitary infusion of methotrexate with systemic leucovorin protection in patients with malignant effusions.

1981 · S B Howell, B B Chu, et al. · Journal of Clinical Investigation · 76

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Ligation of oligonucleotides to nucleic acids or proteins via disulfide bonds

1988 · Barbara C.F. Chu, Leslie E. Orgel · Nucleic Acids Research · 73

Detection of Specific DNA Sequences With Short Biotin-Labeled Probes

1985 · BARBARA C.F. CHU, LESLIE E. ORGEL · DNA · 73

Synthesis of an amplifiable reporter RNA for bioassays

1986 · Barbara C.F. Chu, Fred Russell Kramer, et al. · Nucleic Acids Research · 71

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High Molecular Weight Derivatives of Methotrexate as Chemotherapeutic Agents

1977 · BARBARA C.F. CHU, JOHN M. WHITELEY · Molecular Pharmacology · 53

Increased urinary excretion of nucleic acid and nicotinamide derivatives by rats after treatment with alkylating agents

1975 · Barbara C.F. Chu, Philip D. Lawley · Chemico-Biological Interactions · 35

Increased urinary excretion of pyrimidine and nicotinamide derivatives in rats treated with methyl methane-sulphonate

1974 · Barbara C.F. Chu, Philip D. Lawley · Chemico-Biological Interactions · 28

Differential toxicity of carrier-bound methotrexate toward human lymphocytes, marrow and tumor cells

1981 · Barbara C.F. Chu, Stephen B. Howell · Biochemical Pharmacology · 27

Preparation of ligation intermediates and related polynucleotide pyrophosphates

1984 · Barbara C.F. Chu, Leslie E. Orgel · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · 26

Binding of hairpin and dumbbell DNA to transcription factors

1991 · Barbara C.F. Chu, Leslie E. Orgel · Nucleic Acids Research · 23

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Pharmacological and therapeutic properties of carrier bound methotrexate against tumor confined to a third space body compartment.

1981 · B C Chu, S B Howell · Journal of Pharmacology and Experimental Therapeutics · 21

The Interaction of Carrier-Bound Methotrexate with L1210 Cells

1980 · BARBARA C.F. CHU, JOHN M. WHITELEY · Molecular Pharmacology · 21

Inhibition of DNA synthesis by cross-linking the template to platinum-thiol derivatives of complementary oligodeoxynucleotides

1989 · Barbara C.F. Chu, Leslie E. Orgel · Nucleic Acids Research · 20

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Control of Solid Tumor Metastases With a High-Molecular-Weight Derivative of Methotrexate 2

1979 · Barbara C. F. Chu, John M. Whiteley 5 · JNCI Journal of the National Cancer Institute · 19

Activity of free and carrier-bound methotrexate against transport-deficient and high dihydrofolate dehydrogenase-containing methotrexate-resistant L1210 cells.

1981 · B C Chu, C C Fan, et al. · PubMed · 15

N(4)-amino- and N(4)-hydroxycytosines as base analogue mutagens

1974 · Barbara C.F. Chu, D.M. Brown, et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis · 15

Effect of nitrogen and of catalase on hydroxylamine and hydrazine mutagenesis

1973 · B.C.F. Chu, D.M. Brown, et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis · 15

Crosslinking transcription factors to their recognition sequences with PtIIcomplexes

1992 · Barbara C.F. Chu, Leslie E. Orgel · Nucleic Acids Research · 14

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Optimization of the efficiency of cross-linking PtIIoligonucleotide phosphorothioate complexes to complementary oligonucleotides

1990 · B.C.F. Chu, L.E. Orgel · Nucleic Acids Research · 13

A Simple Procedure for Cross-Linking Complementary Oligonucleotides

1990 · B.C.F. CHU, LESLIE E. ORGEL · DNA and Cell Biology · 8

Peptide-Formation on Cysteine-Containing Peptide Scaffolds

1999 · Barbara C. F. Chu, Leslie E. Orgel · Origins of Life and Evolution of Biospheres · 7

Works count: 36

Citation count: 1,176

H-index: 18

I10-index: 23