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Luke Bu

Biological heterogeneity and versatility of cancer-associated fibroblasts in the tumor microenvironment
2019 · Luke Bu, Hideo Baba, et al. · Oncogene · 333
The effect of smoking on chronic inflammation, immune function and blood cell composition
2020 · Ingrid Elisia, Vivian Lam, et al. · Scientific Reports · 253
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Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination
2021 · Tadahito Yasuda, Mayu Koiwa, et al. · Cell Reports · 170
Cancer-associated fibroblasts reuse cancer-derived lactate to maintain a fibrotic and immunosuppressive microenvironment in pancreatic cancer
2023 · Fumimasa Kitamura, Takashi Semba, et al. · JCI Insight · 133
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Functional diversity of cancer‐associated fibroblasts in modulating drug resistance
2020 · Luke Bu, Hideo Baba, et al. · Cancer Science · 85
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Metabolic shift to serine biosynthesis through 3-PG accumulation and PHGDH induction promotes tumor growth in pancreatic cancer
2021 · Rumi Itoyama, Noriko Yasuda-Yoshihara, et al. · Cancer Letters · 56
Gastric Cancer Stem Cells: Current Insights into the Immune Microenvironment and Therapeutic Targets
2020 · Lingfeng Fu, Luke Bu, et al. · Biomedicines · 55
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Downregulation of 15‐hydroxyprostaglandin dehydrogenase by interleukin‐1β from activated macrophages leads to poor prognosis in pancreatic cancer
2017 · Kota Arima, Yoshihiro Komohara, et al. · Cancer Science · 52
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Transcriptional and Translational Dual-regulated Oncolytic Herpes Simplex Virus Type 1 for Targeting Prostate Tumors
2010 · Cleo YF Lee, Luke XX Bu, et al. · Molecular Therapy · 50
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IL-1β derived from mixed-polarized macrophages activates fibroblasts and synergistically forms a cancer-promoting microenvironment
2022 · Jun Zhang, Lingfeng Fu, et al. · Gastric Cancer · 41
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UV-inactivated HSV-1 potently activates NK cell killing of leukemic cells
2016 · Ismael Samudio, Katayoun Rezvani, et al. · Blood · 41
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Exploratory examination of inflammation state, immune response and blood cell composition in a human obese cohort to identify potential markers predicting cancer risk
2020 · Ingrid Elisia, Vivian Lam, et al. · PLoS ONE · 36
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Effect of age on chronic inflammation and responsiveness to bacterial and viral challenges
2017 · Ingrid Elisia, Vivian Lam, et al. · PLoS ONE · 35
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Intracellular MUC20 variant 2 maintains mitochondrial calcium homeostasis and enhances drug resistance in gastric cancer
2022 · Lingfeng Fu, Atsuko Yonemura, et al. · Gastric Cancer · 33
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Inhibition of 15-PGDH causes Kras-driven tumor expansion through prostaglandin E2-ALDH1 signaling in the pancreas
2018 · Kota Arima, Masaki Ohmuraya, et al. · Oncogene · 27
20S-Protopanaxadiol Inhibits P-Glycoprotein in Multidrug Resistant Cancer Cells
2009 · Yan Zhao, Luke Bu, et al. · Planta Medica · 23
Tumor microenvironmental 15‐PGDH depletion promotes fibrotic tumor formation and angiogenesis in pancreatic cancer
2022 · Luke Bu, Atsuko Yonemura, et al. · Cancer Science · 21
Tumour-specific triple-regulated oncolytic herpes virus to target glioma
2016 · Zahid M. Delwar, Guoyu Liu, et al. · Oncotarget · 20
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Downregulation of 15-PGDH enhances MASH-HCC development via fatty acid-induced T-cell exhaustion
2023 · Xichen Hu, Tadahito Yasuda, et al. · JHEP Reports · 17
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UV Light–inactivated HSV-1 Stimulates Natural Killer Cell–induced Killing of Prostate Cancer Cells
2019 · Ismael Samudio, Elyse Hofs, et al. · Journal of Immunotherapy · 9
A novel tdTomato transgenic mouse model to visualize FAP‐positive cancer‐associated fibroblasts
2022 · Feng Wei, Tomoyuki Uchihara, et al. · FEBS Journal · 5
Prophylactic Vaccination and Intratumoral Boost with HER2-Expressing Oncolytic Herpes Simplex Virus Induces Robust and Persistent Immune Response against HER2-Positive Tumor Cells
2023 · Zahid Delwar, Olga Tatsiy, et al. · Vaccines · 4
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Abstract 5205: VG2025: Transcriptional and translational dually regulated (TTDR) oncolytic virus for cancer immunotherapy
2022 · Yanal Murad, Guoyu Liu, et al. · Cancer Research · 1
Abstract B059: Synergistic activation of antitumor immunity by an oncolytic virus VG161 armed with multiple immune-stimulating genes
2019 · Ronghua Zhao, Jun Ding, et al. · Cancer Immunology Research · 1
Abstract 1987: Expansion of pancreatic cancer stem-like cells through PGE2 accumulation in inflammatory environment
2018 · Takatsugu Ishimoto, Kota Arima, et al. · Cancer Research · 1
Works count: 30
Citation count: 1,502
H-index: 18
I10-index: 19
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