Get started
Author

Campbell McInnes

2-Anilino-4-(thiazol-5-yl)pyrimidine CDK Inhibitors: Synthesis, SAR Analysis, X-ray Crystallography, and Biological Activity
2004 · Shudong Wang, Christopher Meades, et al. · Journal of Medicinal Chemistry · 153
Structure of Free MDM2 N-terminal Domain Reveals Conformational Adjustments that Accompany p53-binding
2005 · Stanislava Uhrinova, Dusan Uhrin, et al. · Journal of Molecular Biology · 141
Structural and biochemical studies of human proliferating cell nuclear antigen complexes provide a rationale for cyclin association and inhibitor design
2005 · George Kontopidis, Su-Ying Wu, et al. · Proceedings of the National Academy of Sciences · 126
Discovery of a Novel Family of CDK Inhibitors with the Program LIDAEUS
2003 · Su Ying Wu, Iain McNae, et al. · Structure · 108
PDF
Development of the Structural Basis for Antimicrobial and Hemolytic Activities of Peptides Based on Gramicidin S and Design of Novel Analogs Using NMR Spectroscopy
2000 · Campbell McInnes, Leslie H. Kondejewski, et al. · Journal of Biological Chemistry · 69
Insights into Cyclin Groove Recognition
2003 · George Kontopidis, Martin J.I. Andrews, et al. · Structure · 61
PDF
Highly potent p21WAF1‐derived peptide inhibitors of CDK‐mediated pRb phosphorylation: Delineation and structural insight into their interactions with cyclin A
2002 · D.I. Zheleva, C. McInnes, et al. · Journal of Peptide Research · 60
Design, synthesis, biological activity and structural analysis of cyclic peptide inhibitors targeting the substrate recruitment site of cyclin-dependent kinase complexes
2004 · Martin J. I. Andrews, Campbell McInnes, et al. · Organic & Biomolecular Chemistry · 57
Design of a versatile linker for solid phase peptide synthesis: Synthesis of C-terminal primary/seconary amides and hydrazides
1993 · R. Ramage, S.L. Irving, et al. · Tetrahedron Letters · 54
Design, Synthesis, and Evaluation of 2-Methyl- and 2-Amino-N-aryl-4,5-dihydrothiazolo[4,5-h]quinazolin-8-amines as Ring-Constrained 2-Anilino-4-(thiazol-5-yl)pyrimidine Cyclin-Dependent Kinase Inhibitors
2010 · Neil A. McIntyre, Campbell McInnes, et al. · Journal of Medicinal Chemistry · 35
Peptide inhibitors of CDK2-cyclin A that target the cyclin recruitment-Site: structural variants of the C-Terminal Phe
2002 · Gail E Atkinson, Angela Cowan, et al. · Bioorganic & Medicinal Chemistry Letters · 18
Improved lead-finding for kinase targets using high-throughput docking.
2006 · Campbell McInnes · PubMed · 9
Conformational differences between cis and trans proline isomers of a peptide antigen representing the receptor binding domain of Pseudomonas aeruginosa as studied by 1H‐nmr
1994 · Campbell Mcinnes, Cyril M. Kay, et al. · Biopolymers · 8
Structure-based discovery and optimization of potential cancer therapeutics targeting the cell cycle.
2006 · Mark P Thomas, Campbell McInnes · PubMed · 7
Abstract 5018: PROTAC degraders of CDK8/CDK19 Mediator kinases potently suppress multiple myeloma proliferation
2023 · Li Zhang, Jing Li, et al. · Cancer Research · 1
Modulation of specificity in cyclic antimicrobial peptides by amphipathicity
2006 · Leslie H. Kondejewski, Campbell McInnes, et al. · Kluwer Academic Publishers eBooks · 1
Structural and biochemical studies of human PCNA complexes provide the basis for association with CDK/cyclin and a rationale for inhibitor design
2004 · G. Kontopidis, S.-Y. Wu, et al. · Acta Crystallographica Section A Foundations of Crystallography · 1
Therapeutic Degradation of Protein Kinases Through PROTACs: Current Status and Future Potential
2020 · Li Zhang, Campbell McInnes · Medicinal chemistry reviews
Abstract LB-198: Design and synthesis of non-ATP competitive inhibitors of CDK4/Cyclin D using REPLACE
2011 · Shu Liu, Padmavathy Nandha Premnath, et al. · Cancer Research
Cambridge Healthtech Institute fourth annual conference in structure-based drug design.
2004 · Campbell McInnes · PubMed
HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR N-[4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-N',N'-dimethyl-benzene-1,4-diamine
2003 · S. Wang, C. Meades, et al. · Worldwide Protein Data Bank
HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR 4-[4-(4-Methyl-2-methylamino-thiazol-5-yl)-pyrimidin-2-ylamino]-phenol
2003 · S. Wang, C. Meades, et al. · Worldwide Protein Data Bank
HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR [4-(2-Amino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine
2003 · S. Wang, C. Meades, et al. · Worldwide Protein Data Bank
HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR 4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-ylamine
2003 · S.Y. Wu, I. McNae, et al. · Worldwide Protein Data Bank
ChemInform Abstract: Design of a Versatile Linker for Solid Phase Peptide Synthesis: Synthesis of C‐Terminal Primary/Seconary Amides and Hydrazides.
1994 · R. RAMAGE, S. L. IRVING, et al. · ChemInform
Works count: 27
Citation count: 909
H-index: 11
I10-index: 11
Year
Topic
Type